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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:23 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 282 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Control lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Comfort Evaluation of Two Marketed Spherical Contact Lenses

NCT02356692
View directory record Official record
Conditions
Astigmatism
Interventions
enfilcon A, senofilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 38 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
3
States / cities
Birmingham, Alabama • Jacksonville, Florida • Lafayette, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Corneal Refractive Therapy Design Comparison for -4 to -6 Diopter Treatment for Overnight Wear for Myopia

NCT05438615
View directory record Official record
Conditions
Myopia
Interventions
Corneal Refractive Therapy-spherical, Corneal Refractive Therapy-aspherical
Other
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Approved and Investigational Contact Lenses

NCT02669095
View directory record Official record
Conditions
Visual Disorder
Interventions
Investigational Contact Lenses (Test), Marketed Contact Lenses (Control)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Sarasota, Florida • Winter Park, Florida • Pickens, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2017 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Prototype Lenses With Experimental UV/HEV Blocker

NCT04885296
View directory record Official record
Conditions
Visual Acuity
Interventions
TRP-200, JJVC Marketed Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
12
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Multifocal Toric Contact Lenses

NCT03208088
View directory record Official record
Conditions
Visual Acuity
Interventions
etafilcon A Investigational Toric Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
7
States / cities
Whittier, California • Orlando, Florida • Kahului, Hawaii + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Oct 21, 2026, 5:23 PM EDT
Terminated Not applicable Interventional Results available

Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens, Model DEN00V

NCT05574959
View directory record Official record
Conditions
Cataracts
Interventions
investigational IOL Model DEN00V, control IOL Model ZCB00/DCB00
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
10
States / cities
Bakersfield, California • Long Beach, California • Torrance, California + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 21, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Children's Viewing Behavior

NCT07229365
View directory record Official record
Conditions
Myopia, Myopia Progression, Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
7 Years to 14 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Vision Performance Evaluation of TECNIS EYHANCE™ With TECNIS SIMPLICITY™ Compared to TECNIS® 1-piece Intraocular Lenses

NCT05025345
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Eyhance, Tecnis 1 piece IOL
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
15
States / cities
Bakersfield, California • Long Beach, California • Sarasota, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens

NCT03633695
View directory record Official record
Conditions
Cataract, Presbyopia
Interventions
IC-8 IOL Group, Control Group
Device
Lead sponsor
AcuFocus, Inc.
Industry
Eligibility
22 Years and older
Enrollment
453 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
21
States / cities
Tucson, Arizona • Bakersfield, California • Laguna Hills, California + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Oct 21, 2026, 5:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)

NCT04807361
View directory record Official record
Conditions
Accomodation, Biofeedback Training, Myopia
Interventions
Auditory biofeedback traing
Behavioral
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
8 Years to 15 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Long Beach, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Silicone Hydrogel Daily Disposable Contact Lenses

NCT02595502
View directory record Official record
Conditions
Vision Disorders
Interventions
JJVC Marketed Contact Lens (Test), Competitor Marketed Contact Lens (Control)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
286 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
13
States / cities
Montgomery, Alabama • Fruit Cove, Florida • Sarasota, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses

NCT02537522
View directory record Official record
Conditions
Contact Lens Base Curve (BC) Fit and Comfort
Interventions
Contact Lenses with 8.5 BC, Contact Lenses with 9.0 BC
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Phase 2 Interventional

A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03.

NCT06780306
View directory record Official record
Conditions
Dry Eye, Dry Eye Disease (DED), Dry Eye Disease With Severe Keratitis
Interventions
TTAX03, Saline (NaCl 0,9 %) (placebo)
Biological
Lead sponsor
BioTissue Holdings, Inc
Industry
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
9
States / cities
Berkeley, California • Deerfield Beach, Florida • Chaska, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 21, 2026, 5:23 PM EDT
Recruiting Phase 1Phase 2 Interventional

Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema

NCT04225611
View directory record Official record
Conditions
Cystoid Macular Edema
Interventions
Dexamethasone
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Tangible Boost Replenishing System

NCT03073148
View directory record Official record
Conditions
Contact Lens Solution
Interventions
Tangible Boost, Placebo saline
Device · Other
Lead sponsor
Tangible Science
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Phase 3 Interventional Results available

Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old

NCT00944710
View directory record Official record
Conditions
Amblyopia
Interventions
Atropine, Plano lens
Drug · Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Fullerton, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 21, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

NCT07408154
View directory record Official record
Conditions
Open-angle Glaucoma (OAG), Ocular Hypertension (OHT)
Interventions
Direct Selective laser Trabeculoplasty
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 5:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Relationship Between Advanced Glycation Endproducts and Diabetes

NCT02662010
View directory record Official record
Conditions
Diabetic Retinopathy, Type 2 Diabetes Mellitus
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
60 Years to 80 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Etafilcon A Daily Disposable Lenses

NCT02061592
View directory record Official record
Conditions
Myopia
Interventions
etafilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
7
States / cities
Jacksonville, Florida • Honolulu, Hawaii • Kahului, Hawaii + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Performance of a Daily Disposable Contact Lens

NCT01192126
View directory record Official record
Conditions
Myopia, Contact Lenses
Interventions
Bausch & Lomb new daily disposable, Johnson & Johnson Acuvue Moist
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 3, 2014 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology to Evaluate Overall Visual Acuity.

NCT05361304
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A contact lenses made with a novel manufacturing technology, senofilcon A contact lenses made with the current manufacturing technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Investigation of the Next Generation Intraocular Lens

NCT03500198
View directory record Official record
Conditions
Cataract
Interventions
Investigational Intraocular Lens Device #1: Next Generation TECNIS IOL, Control Monofocal Intraocular Lens: TECNIS Monofocal IOL
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
247 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
10
States / cities
Torrance, California • Bradenton, Florida • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Oct 21, 2026, 5:23 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Visual Performance of Soft Contact Lenses With Myopia Control Optics

NCT05141448
View directory record Official record
Conditions
Visual Acuity
Interventions
1-Day Acuvue Moist, EMO-118, EMO-114, MiSight® 1 day
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05101252
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A C3, Dailies Total 1 Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Roswell, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2023 · Synced Oct 21, 2026, 5:23 PM EDT