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Showing 73–96 of 282 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Vistakon Investigational Contact Lenses Worn for Daily Wear

NCT00717249
Conditions
Myopia
Interventions
galyifilcon A control lens, galyfilcon A with a silver additive
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
20
States / cities
Fresno, California • Mission Viejo, California • Louisville, Colorado + 17 more
Conditions
Myopia
Interventions
Control Lens (stenfilcon A), Test Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
4
States / cities
Pittsburg, Kansas • Medina, Minnesota • State College, Pennsylvania + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss

NCT03653715
Conditions
Presbyopia
Interventions
Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens, Clerio Vision Single Vision Contact Lens
Device
Lead sponsor
Clerio Vision, Inc.
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Results available

Clinical Investigation of the Next-Generation Intraocular Lens

NCT03111550
Conditions
Cataract
Interventions
Investigational Intraocular Lens Device #1: TECNIS Model ZHR00, Investigational Intraocular Lens Device #2: TECNIS Model ZQR00, TECNIS Symfony® Extended Range of Vision Intraocular Lens: Model ZXR00
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
22 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
12
States / cities
Bakersfield, California • Beverly Hills, California • Sioux City, Iowa + 9 more
Completed Phase 3 Interventional Accepts healthy volunteers

LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear

NCT01735045
Conditions
Myopia
Interventions
Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
Device
Lead sponsor
Szabocsik and Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
5
States / cities
Huntington Beach, California • Honolulu, Hawaii • Oak Lawn, Illinois + 2 more
Conditions
Meibomian Gland Dysfunction, Dry Eye
Interventions
LipiFlow treatment
Device
Lead sponsor
TearScience, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
Birmingham, Alabama • Morrow, Georgia • Charlotte, North Carolina + 2 more
Completed Not applicable Interventional Results available

Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia

NCT04827147
Conditions
Homonymous Hemianopia
Interventions
Multi-Periscopic Prism (MPP) glasses, Fresnel Peripheral Prism (FPP) glasses
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
7 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Denver, Colorado • Palm Springs, Florida + 3 more
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Color Correcting Lenses on Color Vision Deficiency

NCT05463016
Conditions
Color Blindness, Color Vision Defects, Color Blindness, Green, Color Blindness, Red
Interventions
Experimental Group 1: Color Correcting Lenses, Placebo Group 1: Placebo Lenses, Placebo Group 1 Crosses over to become Experimental Group 2: Color Correcting Lenses, Experimental Group 1 Crosses over to become Placebo Group 2: Placebo Lenses, Color Correcting Lenses in Subjects with Normal Color Vision
Device
Lead sponsor
University of the Incarnate Word
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions

NCT01024855
Conditions
Myopia, Hyperopia, Astigmatism
Interventions
RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Santa Ana, California
Completed No phase listed Observational Accepts healthy volunteers

Long Term Outcomes of Vivity Intra Ocular Lens(IOL) Versus Control

NCT04561570
Conditions
Cataract
Interventions
Vivity ACRYSOF IQ IOL Group, ACRYSOF IQ IOL Control Group
Device
Lead sponsor
John Berdahl, MD
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Conditions
Cataract
Interventions
ACRYSOF® IQ Extended Depth of Focus IOL, ACRYSOF® IQ Monofocal IOL, Cataract surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
11
States / cities
Birmingham, Alabama • Fort Collins, Colorado • Bradenton, Florida + 8 more
Conditions
Demodex Blepharitis
Interventions
Lotilaner ophthalmic solution, 0.25%, Vehicle control
Drug
Lead sponsor
Tarsus Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
14
States / cities
Cave Creek, Arizona • Long Beach, California • Colorado Springs, Colorado + 11 more
Conditions
Postoperative Ocular Inflammation, Postoperative Ocular Pain
Interventions
Sham (No Treatment), TRIESENCE (triamcinolone acetonide injectable suspension)
Procedure · Drug
Lead sponsor
Harrow Inc
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Kansas City, Missouri
Completed Not applicable Interventional Results available

Senofilcon A Investigational Manufacturing Process

NCT01951703
Conditions
Visual Acuity, Comfort, Overall Vision
Interventions
senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
4
States / cities
Jacksonville, Florida • Bloomington, Illinois • Pittsburg, Kansas + 1 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Approved Contact Lenses (CR-6657)

NCT07819305
Conditions
Visual Acuity
Interventions
Test (Senofilcon A), Control (Serafilcon A)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
8
States / cities
Jacksonville, Florida • Franklin Park, Illinois • Camden, New York + 5 more
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process

NCT03605303
Conditions
Refractive Error Correction
Interventions
Test/Control, Control/Test
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Allergic Conjunctivitis
Interventions
Ketotifen with a Contact Lens (generic name not yet established)
Drug
Lead sponsor
Vistakon Pharmaceuticals
Industry
Eligibility
8 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
3
States / cities
Los Angeles, California • Charlotte, North Carolina • Memphis, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05291936
Conditions
Ocular Physiology
Interventions
PRECISION1® for Astigmatism Contact Lenses, MyDay® Toric Soft Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Vestal, New York + 2 more
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software

NCT05389072
Conditions
Myopia
Interventions
control contact lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
6 Years to 35 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
San Diego, California • Glenview, Illinois • Bellaire, Texas
Conditions
Dry Eye
Interventions
Investigational Lubricating Eye Drop in a Novelia® bottle, Blink® Tears eye Drops
Drug
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
8
States / cities
Jacksonville, Florida • Pittsburg, Kansas • Medina, Minnesota + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05258149
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Completed Not applicable Interventional Results available

One Week Assessment of The Phenacite Lens

NCT02553395
Conditions
Myopia
Interventions
Phenacite (Test) contact lens, comfilcon A contact lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Corneal Staining
Interventions
Opti-Free RepleniSH, ReNu MultiPlus, Balafilcon A, Unisol 4
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Hybrid SA RGP Center/S-H Skirt Daily Wear 90 Day Multicenter Study

NCT00804505
Conditions
Corneal Disease, Hypersensitivity
Interventions
SynergEyes Hybrid (petrafocon A hem-larafilcon A) Hybrid Contact Lens, SynergEyes Hybrid (paflufocon D hem-iberfilcon A) Contact Lens
Device
Lead sponsor
SynergEyes, Inc.
Industry
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
8
States / cities
San Diego, California • Sunnyvale, California • Andover, Massachusetts + 5 more