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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:21 AM EDT

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Showing 193–216 of 282 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Control lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens

NCT04189224
View directory record Official record
Conditions
Presbyopia
Interventions
JJV Investigational Multifocal Contact Lens, 1-Day Acuvue® Moist Brand Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
4
States / cities
Maitland, Florida • Raytown, Missouri • Granville, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

Comparison of New Contact Lens With Current Marketed Lens

NCT03360110
View directory record Official record
Conditions
Myopia
Interventions
Phoebe test lens, stenfilcon A lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism

NCT01496066
View directory record Official record
Conditions
Cataract
Interventions
LAL (Light Adjustable Lens) and Light Deliver Device (LDD), Monofocal control IOL
Device
Lead sponsor
Calhoun Vision, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
17
States / cities
Fayetteville, Arkansas • Los Angeles, California • Torrance, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

RxSight Light Adjustable Lens and Light Delivery Device New Enrollment Study

NCT05202808
View directory record Official record
Conditions
Aphakia, Cataract
Interventions
Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
14
States / cities
Fayetteville, Arkansas • Chico, California • Largo, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT06749496
View directory record Official record
Conditions
Astigmatism
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of 12 Month Daily Wear of Two Novel O2 Permeable Silicone Hydrogel CLs (HOP/SiH) and A Control, Standard O2 Lens

NCT00344643
View directory record Official record
Conditions
Contact Lenses, Extended-Wear
Interventions
Silicone Hydrogel Soft Contact Lenses
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 38 Years
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2008 · Synced Oct 22, 2026, 7:21 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Can Distance Center and Near Center Multifocal Contact Lenses Control Myopia Progression in Children?

NCT03519490
View directory record Official record
Conditions
Myopia, Myopia, Progressive
Interventions
Hybrid Contact Lens
Device
Lead sponsor
Thomas A. Aller, OD
Other
Eligibility
7 Years to 14 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Bruno, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Myopia Control With a Innovative Spectacle Lens

NCT05174780
View directory record Official record
Conditions
Myopia
Interventions
innovative myopia control spectacle lens, Single vision spectacle lens
Device
Lead sponsor
Essilor International
Industry
Eligibility
6 Years to 12 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
9
States / cities
San Diego, California • Longwood, Florida • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

A Dispensing Comparison of a Test Daily 1 Day Lens Against a Control 1 Day Lens.

NCT03951610
View directory record Official record
Conditions
Myopia
Interventions
Test lens, Control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Anaheim, California • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancement of Emmetropization in Highly Hyperopic Infants

NCT03669146
View directory record Official record
Conditions
Hyperopia
Interventions
Glasses
Device
Lead sponsor
Donald O Mutti, OD, PhD
Other
Eligibility
8 Weeks to 15 Weeks
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 22, 2026, 7:21 AM EDT
Terminated No phase listed Interventional Results available

A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus

NCT04177771
View directory record Official record
Conditions
Aphakia, Cataract, Presbyopia
Interventions
Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Approved Contact Lenses

NCT02759692
View directory record Official record
Conditions
Visual Acuity
Interventions
TEST Contact Lens, CONTROL Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
13
States / cities
Montgomery, Alabama • Jacksonville, Florida • Sarasota, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses

NCT03417557
View directory record Official record
Conditions
Presbyopia
Interventions
Comfilcon A lens (test), Omafilcon B lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Contact Lens and Myopia Control in Optometry School Students

NCT04334369
View directory record Official record
Conditions
Myopia, Progressive
Interventions
Proclear Single Vision Contact Lenses manufactured by CooperVision, Proclear Multifocal Contact Lenses manufactured by CooperVision
Device
Lead sponsor
Jeff Rabin
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens

NCT02487160
View directory record Official record
Conditions
Cataracts, Presbyopia
Interventions
SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
Device
Lead sponsor
Lenstec Incorporated
Industry
Eligibility
22 Years and older
Enrollment
499 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
13
States / cities
Dothan, Alabama • Santa Maria, California • Cape Coral, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS

NCT05299723
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Acute Coronary Syndrome
Interventions
BLT Intervention, BLB Intervention, Sleep Hygiene Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 1

NCT05811338
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Project 1 - Phase 2: VR Program for Social, Activity, and Cognitive Engagement, Project 1 - Phase 2: Tablet for Social, Activity, and Cognitive Engagement
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tallahassee, Florida • Champaign, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Orthokeratology in Myopia Control

NCT03465748
View directory record Official record
Conditions
Myopia
Interventions
OrthoK
Device
Lead sponsor
Illinois College of Optometry
Other
Eligibility
6 Years to 13 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

A Safety and Effectiveness Study of a New Multi-Purpose Contact Lens Care Solution

NCT03537248
View directory record Official record
Conditions
Contact Lens Wear
Interventions
ASP-57, ReNu® Multiplus
Device
Lead sponsor
Asepticys LLC
Industry
Eligibility
18 Years and older
Enrollment
315 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
14
States / cities
Irvine, California • San Diego, California • Longwood, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Different Daily Disposable Silicone Hydrogel Contact Lenses

NCT05805059
View directory record Official record
Conditions
Myopia
Interventions
Control Contact Lens (stenfilcon A), Test Contact Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Ocoee, Florida • Vestal, New York • Granville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses

NCT04968925
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Precision 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
10
States / cities
Mission Viejo, California • Maitland, Florida • Orange Park, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

Together Overcoming Diabetes

NCT04734015
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Together Overcoming Diabetes (TOD)
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
10 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Duluth, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light

NCT05344560
View directory record Official record
Conditions
Visual Acuity
Interventions
soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Not applicable Interventional

A Type I Hybrid Effectiveness-Implementation Trial of MIO

NCT07168642
View directory record Official record
Conditions
Substance Use Disorder
Interventions
Mothering from the Inside Out
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 22, 2026, 7:21 AM EDT