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Conditions: Substance Use Disorders
Interventions: Community Support Intervention Group, Substance Use Disorder Educational Group; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 75 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Abuse, HIV
Interventions: Computer-facilitated HIV intervention, Attention Control; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 371 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sex Trafficking, HIV, Substance Use (Drugs, Alcohol), Mental Health, Sexual Violence, Treatment Engagement
Interventions: CONNECT; Behavioral
Lead sponsor: Lifespan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Substance Abuse
Interventions: CASPAR/Treatment Planning; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 352 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 7
States / cities: Camden, New Jersey • Cape May Court House, New Jersey • Collingswood, New Jersey + 4 more

Conditions: Substance-Related Disorders, HIV
Interventions: Contingency Management; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Generalized Anxiety Disorder
Interventions: Placebo, DT120; Other · Drug
Lead sponsor: Definium Therapeutics US, Inc.; Industry
Eligibility: 18 Years to 74 Years
Enrollment: 245 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 13
States / cities: Little Rock, Arkansas • Los Angeles, California • Bradenton, Florida + 9 more

Conditions: Opioid-use Disorder, Medication Assisted Treatment, Substance Use Disorders
Interventions: Mindfulness based relapse prevention and peer mentoring; Behavioral
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 19 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Birmingham, Alabama • Homewood, Alabama

Conditions: Urinary Tract Infections, Catheter Infection, Catheter-Related Infections
Interventions: Catheter insertion with Povidone Iodine, Standard of care catheter insertion; Drug · Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Substance Abuse, Risk Reduction, RIsky Sexual Behavior
Interventions: Handbook condition, Handbook plus condition; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 17 Years to 22 Years
Enrollment: 910 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Pullman, Washington

Conditions: Posttraumatic Stress Disorder
Interventions: 12 sessions Anger Management Therapy.; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older · Male only
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: HIV Prevention, HIV Pre-exposure Prophylaxis
Interventions: Client Centered Care Coordination; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older · Male only
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Acute Mountain Sickness (AMS)
Interventions: T89 capsule, Placebo capsule; Drug
Lead sponsor: Tasly Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 853 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Injection Site Bruising
Interventions: Tranexamic acid, Saline, Hyaluronic acid; Drug · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 89 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication, Substance-Related Disorders
Interventions: Motivational Interviewing, Email Feedback, Usual Care; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 100 Years
Enrollment: 614 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Elevated Intraocular Pressure
Interventions: Latanoprost ophthalmic solution, 0.005%, TC-002 latanoprost ophthalmic solution, 0.005%; Drug
Lead sponsor: TearClear Corp; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 20
States / cities: Garden Grove, California • Glendale, California • Mission Hills, California + 16 more

Conditions: HIV, Substance Use Disorder (SUD)
Interventions: Wellness, Intervention Strategies and HIV Care (WISH), Movie Night Club - Attention and Time Matched Control; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Oakland, California • San Francisco, California

Conditions: Opioid-Related Disorders, Stimulant-Related Disorder, Child Neglect, Mental Health Impairment
Interventions: Prevention Adaptation of Families Actively Improving Relationships (PRE-FAIR), Standard Case Management and Referral; Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 16 Years to 30 Years
Enrollment: 241 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Attention, Substance Use
Interventions: Attentional Bias Retraining (ABR), Control Training; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Human Immunodeficiency Virus
Interventions: PATH; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years and older
Enrollment: 309 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: San Ysidro, California

Conditions: Colon Cancer Screening
Interventions: Chewing Sugar-Free Gum During Bowel Preparation, Standard Bowel Prep (2L PEG-ELP), Standard Bowel Prep; Behavioral · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 45 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Towson, Maryland

Conditions: Obesity
Interventions: Lo-Flav, Hi-Flav, Epicatechin, Procyanidins; Dietary Supplement
Lead sponsor: Brooklyn College of the City University of New York; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Alcohol Use Disorder (AUD), Alcohol-Related Disorders
Interventions: Diclofenac 100mg, Diclofenac 75mg, Diclofenac 50mg, Placebo control; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 21 Years to 65 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Catonsville, Maryland

Conditions: Arthritis, Psoriatic
Interventions: CZP 200 mg Q2W, CZP 400 mg Q4W, Placebo; Biological · Other
Lead sponsor: UCB BIOSCIENCES GmbH; Industry
Eligibility: 18 Years and older
Enrollment: 409 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 27
States / cities: Birmingham, Alabama • Tuscaloosa, Alabama • Peoria, Arizona + 24 more

Conditions: Alcohol Use, Personalized Normative Feedback
Interventions: Online Personalized Normative Feedback Intervention Targeting Alcohol Misuse, Mental Health and Substance Use Resources; Behavioral
Lead sponsor: Georgia State University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 461 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Atlanta, Georgia

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Activating Community Support for Substance Users

Reducing High Risk Behavior in Treatment Court

Digital Intervention Delivered Via Street Medicine to Increase HIV and Substance Use Care Among Survivors of Sex Trafficking

Linking Services to Patient Needs for Improved Patient Outcomes (CASPAR)

Expression of Stress Markers During Meth Treatment (EXPRESS+)

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Minds and Mentors Program (MiMP)- R61

Reducing Urinary Tract Infection Rates Using a Controlled Aseptic Protocol for Catheter Insertion

First Years Away From Home: Letting Go and Staying Connected

Telemedicine and Anger Management Groups With PTSD Veterans in the Hawaiian Islands

Client-Centered Care Coordination for Black Men Who Have Sex With Men

Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)

Use of Tranexamic Acid in Facial Fillers

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure

Wellness, Intervention Strategies and HIV Care

Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: PRE-FAIR

Attention Training on Smartphones

Peers Plus Mobile App for Treatment in HIV

Impact of Chewing Gum on Bowel Preparation in Patients Undergoing Colonoscopy

The Randomized Controlled Cocoa-Appetite Trial

Diclofenac Dose Response Study

Certolizumab Pegol in Subjects With Adult Onset Active and Progressive Psoriatic Arthritis

Testing the Efficacy of a Brief Alcohol Intervention Among College Students