- Conditions
- Klippel-Feil Syndrome
- Interventions
- Ventilation, Intubation
- Procedure
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- Not listed
- Enrollment
- 300 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
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Showing 1–15
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- Conditions
- Acute Lung Injury, Acute Respiratory Distress Syndrome, Mechanical Ventilation
- Interventions
- APRV, Conventional MV
- Device
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Coronavirus Infection
- Interventions
- bidirectional oxygenation mouthpiece
- Device
- Lead sponsor
- TMC HealthCare
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 3
- States / cities
- Tucson, Arizona • Stanford, California • Atlanta, Georgia
- Conditions
- Frostbite
- Interventions
- Standard of care plus Epoprostenol infusion for 8 hours (hrs) per day up to 5 days maximum, Standard of Care + Placebo (Normal Saline)infusion for 8 hours per day up to 5 days maximum
- Drug
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Acute Respiratory Distress Syndrome
- Interventions
- A.1 Lucinactant, B.3 SoC, A.2 Lucinactant, A.3 Lucinactant, A.4 Lucinactant, B.1 Lucinactant, B.2 Lucinactant
- Drug · Other
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 16 Years to 75 Years
- Enrollment
- 124 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 1
- States / cities
- Warrington, Pennsylvania
- Conditions
- Diabetes, Periodontitis
- Interventions
- Hyperbaric Oxygen therapy, Conventional Wound Therapies
- Device · Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Airway Management
- Interventions
- Low-flow nasal supplemental oxygen with a conventional nasal cannula during tracheal intubation with the C-MAC video laryngoscope, High-flow nasal supplemental oxygen (Fisher & Paykel, Auckland, New Zealand) during tracheal intubation with the C-MAC video laryngoscope
- Device
- Lead sponsor
- Thomas Riva
- Other
- Eligibility
- Up to 52 Weeks
- Enrollment
- 1,192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Lower Back Pain
- Interventions
- Medical Care + Chiropractic Care, Conventional Medical Care Only
- Other
- Lead sponsor
- RAND
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 750 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 3
- States / cities
- San Diego, California • Pensacola, Florida • Bethesda, Maryland
- Conditions
- Neonatal Respiratory Distress Related Conditions
- Interventions
- Regular Nasal CPAP using a conventional ventilator, High Frequency Nasal CPAP
- Device
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- Up to 4 Months
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Sepsis, Emergency Medical Services, Quality Improvement, Shock, Septic, Fluid Therapy
- Interventions
- Incorporation of Rapid Fluid Infusion Device in Prehospital Suspected Sepsis Protocol, Conventional Prehospital Suspected Sepsis Protocol
- Other
- Lead sponsor
- Orange Park Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Orange Park, Florida
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Blindness
- Interventions
- Supplemental Oxygen Management, Conventional Oxygen Management
- Procedure
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 48 Hours
- Enrollment
- 649 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1994 – 1999
- U.S. locations
- 9
- States / cities
- Palo Alto, California • New Haven, Connecticut • Atlanta, Georgia + 6 more
- Conditions
- Hypoxia
- Interventions
- Chest Worn Pulse Oximeter
- Device
- Lead sponsor
- Perin Health Devices
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Chronic Venous Hypertension Due to Deep Vein Thrombosis, Venous Reflux
- Interventions
- exercise in water, aquatic activity plus conventional management
- Other
- Lead sponsor
- Arizona Cardiovascular Consultants
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 181 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Mesa, Arizona
- Conditions
- Advanced Malignant Mesothelioma, Localized Malignant Mesothelioma, Malignant Ascites, Primary Peritoneal Cavity Cancer, Recurrent Malignant Mesothelioma
- Interventions
- etanidazole, therapeutic conventional surgery, laboratory biomarker analysis
- Drug · Procedure · Other
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2001
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Acute Respiratory Failure, Airway Extubation
- Interventions
- Traditional online education, Interprofessional education, Clinical protocol, Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC), Preventive post-extubation high-flow nasal cannula oxygen (HFNC)
- Behavioral · Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13,018 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 17
- States / cities
- Carlisle, Pennsylvania • Hanover, Pennsylvania • Harrisburg, Pennsylvania + 7 more