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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Conversational Agent/Chatbot Clear all
Completed Not applicable Interventional Results available

Potency and Precision Investigation

NCT06240091
View directory record Official record
Conditions
Depression, Anxiety
Interventions
DISC-MA
Device
Lead sponsor
Woebot Health
Industry
Eligibility
18 Years to 75 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

APOL1 Genetic Testing Program for Living Donors

NCT04910867
View directory record Official record
Conditions
Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
Interventions
Components of Genetic Counseling, APOL1 genetic testing, EHR integration
Behavioral · Diagnostic Test · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

Improving Care for Women With Urinary Incontinence (EMPOWER)

NCT05515198
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Patient Education, Nurse Navigation, ChatBot
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Phase 1Phase 2 Interventional

A Chatbot To Support Substance Use Recovery

NCT06845878
View directory record Official record
Conditions
Opiate-Related Disorders, Opiate Substitution Treatment
Interventions
chatbot
Other
Lead sponsor
Dimagi Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Active, not recruiting Not applicable Interventional

Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening and Enhanced Navigation on Care Delivery for Patients With Breast Cancer

NCT06019988
View directory record Official record
Conditions
Breast Cancer, Social Determinants of Health (SDOH)
Interventions
Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Recruiting Not applicable Interventional

PASCAL Feasibility Study

NCT07301151
View directory record Official record
Conditions
Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
chatbot, no chatbot
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Brief Negotiation Interview Chatbot to Improve Buprenorphine Engagement Among Justice-Involved Individuals

NCT04982627
View directory record Official record
Conditions
Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Criminal Behavior
Interventions
BNI Chatbot, OUD Education & Treatment Resources
Behavioral
Lead sponsor
Center for Progressive Recovery, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Trial of the First Conversational Agent for Smoking Cessation (QuitBot)

NCT03585231
View directory record Official record
Conditions
Smoking Cessation
Interventions
Immediate access to novel messaging program intervention, Immediate access to standard of care messaging program intervention, Delayed access to novel novel messaging program intervention
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
404 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 7, 2020 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Bot-based Self-help Program (WELL)

NCT06208566
View directory record Official record
Conditions
Well-Being, Psychological
Interventions
Conversational Agent Zenny, Web-based Wellness Resources
Behavioral
Lead sponsor
University of Klagenfurt
Other
Eligibility
18 Years and older
Enrollment
1,595 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 3, 2026, 5:13 AM EDT
Not yet recruiting Not applicable Interventional

A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults

NCT07214831
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Large language model-based chatbot brief alcohol intervention session
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 29 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 3, 2026, 5:13 AM EDT
Not yet recruiting Not applicable Interventional

Advancing Scalable Alcohol Brief Interventions in the ED: A Trial of Conversational AI With Digital Reinforcements

NCT07661563
View directory record Official record
Conditions
Alcohol Misuse
Interventions
MICA, TRAC
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Innovative Conversational Agent (Quitbot) for Smoking Cessation

NCT04308759
View directory record Official record
Conditions
Smoking &Amp; Tobacco Cessation
Interventions
Experimental Smoking Cessation Program, Control Smoking Cessation Program
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1,647 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ClientBot: a Conversational Agent That Supports Skills Practice and Feedback for Motivational Interviewing

NCT05479890
View directory record Official record
Conditions
Motivational Interviewing, Alcohol Use Disorder
Interventions
ClientBot
Other
Lead sponsor
Lyssn.io, Inc.
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 3, 2026, 5:13 AM EDT
Not yet recruiting Not applicable Interventional

AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults

NCT07701668
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Social Isolation
Interventions
AI-based conversational intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
75 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

Treatment Uptake Chatbot for Eating Disorders

NCT04806165
View directory record Official record
Conditions
Eating Disorders
Interventions
Repeated Administration, Personalized Recommendation, Motivational Interviewing, Core Modules Only, Motivational Interviewing, Personalized Recommendation, Repeated Administration, Motivational Interviewing, Repeated Administration, Motivational Interviewing, Personalized Recommendation, Personalized Recommendation, Repeated Administration, Psychoeducation, Psychoeducation, Repeated Administration, Psychoeducation, Personalized Recommendation, Psychoeducation, Motivational Interviewing, Psychoeducation, Motivational Interviewing, Personalized Recommendation, Psychoeducation, Personalized Recommendation, Repeated Administration, Psychoeducation, Motivational Interviewing, Repeated Administration, Psychoeducation, Motivational Interviewing, Personalized Recommendation, Repeated Administration
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional

UG3 Pilot Clinical Trial

NCT07073898
View directory record Official record
Conditions
Lung Cancer
Interventions
Repeated Text Messages (TM+), Conversational Agent (CA), Educational Video, Proactive Patient Navigation (PPN), Reactive Patient Navigation (RPN)
Other
Lead sponsor
University of Utah
Other
Eligibility
50 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Active, not recruiting Not applicable Interventional Results available

Implementation Strategies for Monitoring Adherence in Real Time

NCT04347161
View directory record Official record
Conditions
Lung Cancer, Medication Adherence, Symptoms and Signs
Interventions
Conversational Agent/Chatbot, Usual Care
Device · Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 3, 2026, 5:13 AM EDT