Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:19 AM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Well Child Visit, Gaps in Care
Interventions
Automated SMS, Automated SMS + Conversational AI Scheduling Assistance, Traditional Passive Outreach
Behavioral · Other
Lead sponsor
Waymark
Industry
Eligibility
0 Years to 21 Years
Enrollment
2,821 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Conditions
Nonsuicidal Self-injury, Depression, Anxiety
Interventions
App-based digital mental health intervention for adolescent NSSI, App-based delivery of healthy living psychoeducational materials
Device
Lead sponsor
Northwestern University
Other
Eligibility
14 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Parent-Child Relations, Language Development
Interventions
LENA Home
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Months to 9 Months
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources, Primary Health Care and Access to Primary Care, Technology Use to Support Caregivers, Caregiver Burden, Health Status, Child and Infant Care, Preventative Care Services
Interventions
DAPHNE Chatbot Intervention, Standard HRSN Screening and Referral (Usual Care)
Behavioral · Other
Lead sponsor
Emre Sezgin
Other
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Pathways to Prevention Food-is-Medicine Trial

NCT07380243
Conditions
Heart Disease, Cardiovascular Health Status
Interventions
Nutrition Education, PRO-CVH, Healthy Conversation Skills, Medically tailored groceries/cooking classes
Behavioral
Lead sponsor
Amrik Singh Khalsa
Other
Eligibility
6 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Breast Cancer, Social Determinants of Health (SDOH)
Interventions
Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional

UG3 Pilot Clinical Trial

NCT07073898
Conditions
Lung Cancer
Interventions
Repeated Text Messages (TM+), Conversational Agent (CA), Educational Video, Proactive Patient Navigation (PPN), Reactive Patient Navigation (RPN)
Other
Lead sponsor
University of Utah
Other
Eligibility
50 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional

Virtual Nephrologist

NCT06841016
Conditions
Chronic Kidney Disease(CKD)
Interventions
Virtual Nephrologist
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Nashville, Tennessee
Conditions
Autism Spectrum Disorder
Interventions
Treatment as Usual, Early Social Interaction Mobile Coaching (ESI-MC)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
15 Months to 20 Months
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Los Angeles, California • Tallahassee, Florida • Atlanta, Georgia + 5 more
Conditions
Chronic Pain, Mental Health Disorders, Behavioral Health Challenges, Ecological Momentary Assessment Best Practices
Interventions
Digital Biopsychosocial Conversational Data Collection Software, Standard Digital Questionnaire Data Collection
Other
Lead sponsor
AugMend Health Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Large Language Models
Interventions
OpenEvidence, GPT-4
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
25 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Conditions
Hospitalized Children
Interventions
Animal-assisted interaction, Conversational interaction
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
8 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Major Depressive Disorder (MDD)
Interventions
Conversational AI system vs Usual Care
Other
Lead sponsor
George Mason University
Other
Eligibility
18 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fairfax, Virginia
Conditions
Presbyphonia
Interventions
PhoRTE Program, University of California Los Angeles (UCLA) Loneliness Scale, Social Disconnectedness Scale, Patient Health Questionnaire 9, Aging Voice Index, The Edmonton Frail Scale, Vocal Effort Scale, Montreal Cognitive Assessment, Voice Handicap Index-10, Voice Problem Impact Scales, Cough Severity Index, Laryngoscopy, Acoustic, perceptual, and aerodynamic assessments
Other · Procedure
Lead sponsor
Matthew R. Hoffman
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Not listed Not applicable Interventional Accepts healthy volunteers

A Language Intervention Study of Preterm Infants

NCT03688386
Conditions
Language Development, Language Delay, Mother-Infant Interaction, Maternal Behavior
Interventions
Reading intervention, Infant bonding, LENA recording, LENA linguistic feedback, LENA summary
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
23 Weeks to 31 Weeks
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Mental Health Screening Adherence
Interventions
Perinatal Psychoeducation Articles, Bi-weekly Perinatal Mental Health Screening, Chatbot-Guided Journaling, Perinatal-Focused Meditations, Themed Perinatal Learning Pathways
Behavioral
Lead sponsor
Poisera, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Osteoarthritis of Knee, Knee Pain Chronic
Interventions
CAPPA, Health education
Behavioral
Lead sponsor
Marquette University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Human Papilloma Virus
Interventions
Usual Care, ECA-HPV App with Clinic Notification and Adolescent Functions Disabled, ECA-HPV App with Clinic Notification Function Enabled, ECA-HPV App with Adolescent Function Enabled, ECA-HPV App with Clinic Notification and Adolescent Functions Enabled
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
8 Years to 12 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Nonsuicidal Self Injury, Suicidal Ideation, Depression, Anxiety
Interventions
Self-guided digital intervention for NSSI, Digital intervention for NSSI with coaching, Active control
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 24 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet-based Conversational Engagement Clinical Trial

NCT02871921
Conditions
Aging, Mild Cognitive Impairment
Interventions
Conversational Engagement
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
75 Years and older
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Conditions
Language Development, Language, Child, Early Intervention
Interventions
Duet Language Intervention Modules
Behavioral
Lead sponsor
Temple University
Other
Eligibility
12 Months and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
COVID-19
Interventions
Text-Messaging (TM), Conversational Agent (CA), Patient Navigation (PN)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
2,117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Cardiovascular Diseases, Lifestyle Factors
Interventions
Generic text messages, Interactive AI chatbot text messaging, Proactive pharmacist support
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
2,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Denver, Colorado • Fort Lupton, Colorado • Wheat Ridge, Colorado
Conditions
Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain, Overdose of Opiate, Respiratory Depression, Safety Issues
Interventions
Continuous conversational interaction, Remifentanil infusion
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
20 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California