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ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:37 PM EDT

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Showing 1–24 of 243 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Copper gluconate Clear all
Completed Phase 3 Interventional

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

NCT04102371
View directory record Official record
Conditions
Shock, Septic
Interventions
Lactated Ringer, Normal Saline, Plasma-lyte
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Months to 17 Years
Enrollment
9,041 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
22
States / cities
Davis, California • Los Angeles, California • San Francisco, California + 19 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Methicillin-resistant Staphylococcus Aureus (MRSA) Skin and Soft Tissue Infection (SSTI) Prevention in Military Trainees

NCT01105767
View directory record Official record
Conditions
Staphylococcus Aureus, MRSA Skin Infections, Staphylococcal Skin Infections
Interventions
Chlorhexidine gluconate, Supplemental training, education and hygiene
Drug · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 42 Years · Male only
Enrollment
30,209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbus, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Early Phase 1 Interventional Results available

Zinc Effect on Inflammation and Cardiovascular Risk in HIV

NCT05085834
View directory record Official record
Conditions
Inflammation, Cardiovascular Diseases, Zinc Deficiency
Interventions
Zinc Gluconate, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 20, 2026, 11:37 PM EDT
Not listed Phase 1 Interventional

Effect of Zinc on Barrett's Metaplasia

NCT01984580
View directory record Official record
Conditions
Barrett's Metaplasia
Interventions
zinc gluconate
Drug
Lead sponsor
Main Line Health
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 14, 2013 · Synced Oct 20, 2026, 11:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Infection Prophylaxis Prior to Shoulder Surgery

NCT06464770
View directory record Official record
Conditions
Arthroplasty Shoulder, Periprosthetic Joint Infection
Interventions
Chlorhexidine Gluconate
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 89 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chlorhexidine Gluconate Versus Povidone Iodine at Cesarean Delivery: a Randomized Controlled Trial

NCT01975805
View directory record Official record
Conditions
Pregnancy, Cesarean Section
Interventions
Chlorhexidine Gluconate, Povidone Iodine
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 20, 2026, 11:37 PM EDT
Terminated Not applicable Interventional

Microbial Growth in Operative Splash Basins During Total Joint Arthroplasty

NCT04274517
View directory record Official record
Conditions
Periprosthetic Joint Infection
Interventions
Sterile Water, 3.5% Betadine, 0.05% Chlorhexidine Gluconate
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Not applicable Interventional Results available

Hub Cleansing to Prevent Hub Infection

NCT01563406
View directory record Official record
Conditions
Bacteremia
Interventions
15 second scrub, 5 second scrub, 3.15% chlorhexidine/70% isopropyl alcohol, 70% isopropyl alcohol
Other · Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
16 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Oct 20, 2026, 11:37 PM EDT
Terminated Phase 4 Interventional

Study of the Efficacy and Safety of Ferrlecit in the Maintenance Dosing in Hemodialysis Patients.

NCT00223938
View directory record Official record
Conditions
Anemia
Interventions
Oral Iron, sodium ferric gluconate
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
8
States / cities
Hot Springs, Arkansas • Orange County, California • Simi Valley, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 4 Interventional Results available

Diltiazem in the Treatment of Atrial Fibrillation or Atrial Flutter With Rapid Ventricular Rate

NCT05661942
View directory record Official record
Conditions
Atrial Fibrillation With Rapid Ventricular Response, Hypotension Drug-Induced
Interventions
Calcium pre-treatment, Placebo
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Subjects

NCT02222896
View directory record Official record
Conditions
Surgery
Interventions
Chlorhexidine Gluconate, Vehicle, DynaHex-2
Drug · Other
Lead sponsor
Medline Industries
Industry
Eligibility
16 Years and older
Enrollment
347 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Sterling, Virginia
Source: ClinicalTrials.gov public record
Updated May 21, 2021 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Not applicable Interventional Results available

Alveolar Microperforation for Inflammation-Enhanced Tooth Movement During Orthodontic Treatment

NCT01720797
View directory record Official record
Conditions
Malocclusion
Interventions
Micro-osteoperforation, Anesthestic, Chlorhexidine
Device · Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 19, 2015 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Use of Sodium Stibogluconate as a Treatment for Leishmaniasis

NCT00657618
View directory record Official record
Conditions
Leishmaniasis
Interventions
Sodium Stibogluconate (SSG)
Drug
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
Not listed
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Pilot Evaluation of Two Test Materials With a Positive Control When Used as a Patient Preoperative Skin Preparation

NCT03861780
View directory record Official record
Conditions
Bacteria Microflora Reduction
Interventions
Project X 26ml, Project X 5.1ml, Prevantics Maxi Swabstick
Drug
Lead sponsor
Professional Disposables International, Inc.
Industry
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 20, 2026, 11:37 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

In-vivo Efficacy Study of Patient Preoperative Preps

NCT01968356
View directory record Official record
Conditions
Skin Flora Bacterial Reduction Post-product Application
Interventions
3M CHG/IPA Prep Colorless, 3M CHG/IPA Prep Tint, ChloraPrep, Saline
Drug
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Oct 20, 2026, 11:37 PM EDT
Not listed Phase 1Phase 2 Interventional

Single-dose Potassium Supplementation in Patients With ADHD for Whom the Anesthetic Lidocaine is Ineffective

NCT03563573
View directory record Official record
Conditions
ADHD
Interventions
Potassium Gluconate Oral Capsule, Placebo oral capsule
Drug
Lead sponsor
AlkaliDx, Inc.
Industry
Eligibility
13 Years to 49 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 20, 2018 · Synced Oct 20, 2026, 11:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.

NCT07239219
View directory record Official record
Conditions
Urinary Tract Infection, Antibiotic, Catheter Infection
Interventions
0.05% Chlorhexidine Gluconate, Normal Saline
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)

NCT02296645
View directory record Official record
Conditions
Surgical Site Infection
Interventions
ZuraPrep, ChloraPrep
Drug
Lead sponsor
Zurex Pharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Sterling, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 14, 2016 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Irrisept C.Acnes Study

NCT03938467
View directory record Official record
Conditions
Rate of Positive Culture Growth for C.Acnes From Specimens Obtained From the Shoulders of Patients Undergoing Primary Shoulder Arthroplasty
Interventions
Antiseptic Cleanser
Drug
Lead sponsor
Orthopaedic Associates of Michigan, PC
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 21, 2024 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 4 Interventional Results available

Baseline Oral Health Study: UnCoVer the Connections to General Health

NCT04954313
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Type 2
Interventions
Subgingival chlorhexidine irrigation, Dental Supplies, Periodonal Treatment
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
786 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 20, 2026, 11:37 PM EDT
Completed No phase listed Observational

Prehospital Ventilator-Associated Pneumonia Prevention Trial

NCT01902446
View directory record Official record
Conditions
Wounds and Injuries, Respiratory Failure, Pneumonia, Ventilator-Associated
Interventions
Chlorhexidine gluconate
Drug
Lead sponsor
Nicholas M Mohr
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 9, 2017 · Synced Oct 20, 2026, 11:37 PM EDT
Terminated Not applicable Interventional Results available

Vaginal Prep Solutions to Reduce Bacteria Colony Counts in Patients Having a Vaginal Surgery

NCT03854370
View directory record Official record
Conditions
Surgical Site Infection, Vaginal Surgery
Interventions
Baby shampoo, Betadine, Peridex, TechniCare
Other
Lead sponsor
Wright State University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 20, 2026, 11:37 PM EDT
Completed Phase 2 Interventional Results available

Local Heat Therapy Versus Sodium Stibogluconate for the Treatment of Cutaneous Leishmaniasis

NCT00884377
View directory record Official record
Conditions
Cutaneous Leishmaniasis
Interventions
Sodium stibogluconate (Pentostam), ThermoMed
Drug · Device
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 20, 2026, 11:37 PM EDT
Recruiting Phase 4 Interventional

Skin Preparation for Elective Foot and Ankle Surgery

NCT05401292
View directory record Official record
Conditions
Microbial Colonization, Foot and Ankle Disorders
Interventions
Hibiclens, Isopropyl Alcohol 70% Topical Application Solution
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 20, 2026, 11:37 PM EDT