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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Core Body Temperature Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Brain on Whole Body Hyperthermia: A Neuroimaging Study

NCT02062840
View directory record Official record
Conditions
Major Depression
Interventions
High intensity whole-body infrared heating, Low intensity whole-body infrared heating, Functional Magnetic Resonance Imaging (fMRI) and electrocardiogram (EKG), Questionnaires
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 9, 2015 · Synced Sep 1, 2026, 5:14 PM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Use of Water Warming/Cooling Garment to Maintain a Constant Intraoperative Core Target Temperature in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (HIPEC): A Proof-of-Concept Study

NCT05474352
View directory record Official record
Conditions
Hyperthermic Intraperitoneal
Interventions
Allon System
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia

NCT05441449
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Cooling Vest
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 68 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 1, 2026, 5:14 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Enhancing Psychotherapy for Mood Disorders With Whole Body Hyperthermia

NCT02021149
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
High intensity whole-body infrared heating, Psychotherapy, Questionnaires, Low intensity whole-body infrared heating
Device · Behavioral · Other
Lead sponsor
Charles (Chuck) Raison
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 26, 2015 · Synced Sep 1, 2026, 5:14 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Accuracy Validation of the Moni-Patch Temperature Monitoring Patch System

NCT07397078
View directory record Official record
Conditions
Body Temperature, Febrile
Interventions
Moni-Patch Temperature Monitoring Patch System
Device
Lead sponsor
Murata Vios, Inc.
Industry
Eligibility
7 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Woodbury, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 1, 2026, 5:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Body Temperature in Persons With Tetraplegia When Exposed to Heat

NCT01890915
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Heat Exposure
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced Sep 1, 2026, 5:14 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Thermoregulation Among Individuals With First-episode Psychosis

NCT04369677
View directory record Official record
Conditions
Psychosis, First Episode Psychosis
Interventions
Not listed
Lead sponsor
Nicholas Breitborde
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans

NCT01791114
View directory record Official record
Conditions
Insulin Sensitivity, Obesity
Interventions
Cold exposure, Cold exposure plus propranolol, Thermoneutral Conditions, Cold water consumption, Tepid water consumption, Exercise, Meal consumption
Other
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 75 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Sep 1, 2026, 5:14 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Measuring Core Body Temperature Using TempuRing

NCT02462278
View directory record Official record
Conditions
Fertility
Interventions
TempuRing
Device
Lead sponsor
Prima-Temp, Inc
Industry
Eligibility
21 Years to 43 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia and Major Depression (MDD)

NCT01625546
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Whole Body Hyperthermia system
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 9, 2015 · Synced Sep 1, 2026, 5:14 PM EDT
Terminated Not applicable Interventional Results available

Study of a New Clinical Device for Reducing Body Core Temperature

NCT01996982
View directory record Official record
Conditions
Hypothermia
Interventions
CCS Device
Device
Lead sponsor
Seton Healthcare Family
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2019 · Synced Sep 1, 2026, 5:14 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

IEEM- Work:Rest Cycles in Burn Survivors- Humidity

NCT06966336
View directory record Official record
Conditions
Hyperthermia, Burn Injury
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 1, 2026, 5:14 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Sleep and Circadian Contributions to Nighttime Blood Pressure

NCT05656768
View directory record Official record
Conditions
Sleep, Circadian Rhythm, Blood Pressure, Hypertension
Interventions
Constant Routine Protocol
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
1,427 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 1, 2026, 5:14 PM EDT
Completed No phase listed Observational Results available

Comparison Study of Core Temperature Thermometry Systems

NCT01255865
View directory record Official record
Conditions
Thermometry Device Comparisons
Interventions
Not listed
Lead sponsor
3M
Industry
Eligibility
Not listed
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Sep 1, 2026, 5:14 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia (WBH) as a Rapid Treatment for Fibromyalgia

NCT02332694
View directory record Official record
Conditions
Fibromyalgia
Interventions
The Whole Body Hyperthermia system uses water-filtered infrared-A (wIRA) heat radiation
Device
Lead sponsor
Charles (Chuck) Raison
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 26, 2015 · Synced Sep 1, 2026, 5:14 PM EDT
Recruiting Not applicable Interventional

Sauna for Long Covid

NCT05931497
View directory record Official record
Conditions
Long COVID
Interventions
whole body hyperthermia
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors

NCT03304587
View directory record Official record
Conditions
Breast Cancer
Interventions
Polysomnography (PSG), Rectal thermistor 400 Series, Bright blue-green light, Dim red light, Digital foot candle datalogging light meter, Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue, Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance, Patient-Reported Outcomes Measurement Information System (PROMIS)-Depression, Patient-Reported Outcomes Measurement Information System (PROMIS)-Physical Function, Pittsburgh Sleep Quality Index (PSQI), Center for Epidemiological Studies - Depression, Montreal Cognitive Assessment (MoCA), European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ-C30), Daily Log
Diagnostic Test · Other
Lead sponsor
Michigan State University
Other
Eligibility
21 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Sep 1, 2026, 5:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks

NCT05820490
View directory record Official record
Conditions
Metabolic Health
Interventions
Whole Room Calorimeter, Mixed-Meal Tolerance Test (MMTT), Core Body Temperature, Morningness-Eveningness Questionnaire, Muscle Biopsy, Serial Blood Sampling
Other · Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
21 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Early Phase 1 Interventional

Systemic Normothermia in Intracerebral Hemorrhage (ICH)

NCT02078037
View directory record Official record
Conditions
Intracerebral Hemorrhage
Interventions
Arctic Sun cooling device, Standard of Care
Device · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional

Determination of Core Body Temperature in Parturient Warmed With Upper or Underbody Forced Air Cover (Bair Hugger)

NCT05314075
View directory record Official record
Conditions
Cesarean Section
Interventions
Upper Body Forced Air Warming device, Under Body Forced Air Warming device
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older · Female only
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional Results available

HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2

NCT05708976
View directory record Official record
Conditions
Major Depressive Disorder, Depression
Interventions
Cognitive Behavioral Therapy (CBT), Active Whole-Body Hyperthermia (Active WBH), Sham Whole-Body Hyperthermia (Sham WBH)
Behavioral · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 1, 2026, 5:14 PM EDT
Recruiting Not applicable Interventional

Sleep and Circadian Mechanisms in Hypertension

NCT05184933
View directory record Official record
Conditions
Hypertension, Cardiovascular Diseases, Cardiovascular Risk Factors, Circadian Rhythms, Sleep
Interventions
At-home Polysomnography, Circadian Protocol, Rested Wakefulness Trial, Overnight Sleep Trial, Regularized Sleep Schedule
Other · Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 64 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional

Orexin and Tau Pathology in Cognitively Normal Elderly

NCT03053908
View directory record Official record
Conditions
Elderly, Alzheimer Disease
Interventions
Actigraphy, Nocturnal Polysomnograpahy (NPSG)
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Sep 1, 2026, 5:14 PM EDT
Completed Not applicable Interventional Results available

Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery

NCT03111875
View directory record Official record
Conditions
Perioperative Care, Surgery--Complications, Hypothermia; Anesthesia, Myocardial Injury
Interventions
aggressive warming, routine thermal management
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
45 Years and older
Enrollment
5,056 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 1, 2026, 5:14 PM EDT