Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 15, 2026, 10:11 AM EDT

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Showing 337–354 of 354 matching trials from the live ClinicalTrials.gov search.
Conditions
Heart Defects, Congenital, Hypertension, Pulmonary
Interventions
L-citrulline, Placebo of intravenous L-citrulline
Drug
Lead sponsor
Asklepion Pharmaceuticals, LLC
Industry
Eligibility
Up to 17 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Poor Glycemic Control
Interventions
Metformin, Glargine insulin, Glulisine
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Atlanta, Georgia
Conditions
Coronary Disease
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
Up to 7 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
New York, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Identifying Targets of Maladaptive Metabolic Responses in Heart Failure

NCT03032627
Conditions
Heart Failure
Interventions
Collection of discarded heart tissue
Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
19 Years to 89 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Terminated Not applicable Interventional

Del Nido Cardioplegia Randomized Trial

NCT02442050
Conditions
Cardiac Perfusion
Interventions
del Nido solution, Blood-based cardioplegia
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
19 Years to 79 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Falls Church, Virginia
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
20 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Thoracic Surgery, Cardiopulmonary Bypass
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 90 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Phase 4 Interventional Results available

ISCHEMIA-Chronic Kidney Disease Trial

NCT01985360
Conditions
Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia, Kidney Disease, End Stage Renal Failure on Dialysis
Interventions
Cardiac Catheterization, Coronary Artery Bypass Graft Surgery, Percutaneous Coronary Intervention, Lifestyle, Medication
Procedure · Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
777 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Active, not recruiting No phase listed Observational

Cardiopulmonary Bypass Induced Red Blood Cell Lysis

NCT05189262
Conditions
Cardiopulmonary Bypass, Cardiac Surgery, Kidney Injury, Acute
Interventions
Blood and urine collection
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Hypertension
Interventions
nitroglycerin, esmolol
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Hemostasis
Interventions
Fibrinogen Concentrate (FC), Cryoprecipitate
Drug
Lead sponsor
Emory University
Other
Eligibility
1 Day to 30 Days
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Atrial Fibrillation
Interventions
Botulinum Toxin Type A, Placebo
Drug
Lead sponsor
Joseph Mathew, M.D.
Other
Eligibility
50 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Coronary Artery Disease
Interventions
Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI)
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2039
U.S. locations
18
States / cities
Glendale, California • Atlanta, Georgia • Carmel, Indiana + 12 more
Conditions
Coronary Artery Disease
Interventions
Hybrid CABG/PCI, Off Pump CABG
Procedure
Lead sponsor
Pinnacle Health Cardiovascular Institute
Network
Eligibility
Not listed
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
1
States / cities
Harrisburg, Pennsylvania
Conditions
Pain
Interventions
Parecoxib Sodium/Valdecoxib, Placebo/Valdecoxib, Placebo/Placebo
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,671 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
84
States / cities
Fairhope, Alabama • Mobile, Alabama • Tucson, Arizona + 61 more
Conditions
Acute Kidney Insufficiency, Acute Renal Insufficiency, Acute Kidney Injury, Ischemic Preconditioning
Interventions
Remote Ischemic Preconditioning
Procedure
Lead sponsor
Robert Kramer, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Portland, Maine
Completed Not applicable Interventional Results available

Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)

NCT04976530
Conditions
Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative
Interventions
DrugSorb-ATR system, Sham comparator
Device
Lead sponsor
CytoSorbents, Inc
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
22
States / cities
Sacramento, California • New Haven, Connecticut • Washington D.C., District of Columbia + 18 more
Conditions
Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Neonatal Sepsis
Interventions
Renal Angina Index (RAI)
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio