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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Couples' Cognitive Behavioral Therapy Clear all
Completed Not applicable Interventional

A Couples Approach to Enhance Breast Cancer Survivorship

NCT00665899
View directory record Official record
Conditions
Early-Stage Breast Cancer
Interventions
Cancer-Focused Relationship Enhancement, Couple's Cancer Education
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Not listed
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

Uniting Couples In the Treatment of Eating Disorders (UNITE)

NCT02419326
View directory record Official record
Conditions
Binge-eating Disorder, Eating Disorder
Interventions
Psychotherapy treatment
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

Intensive Weekend Retreat Multi-Couple Group Therapy for PTSD

NCT03158558
View directory record Official record
Conditions
PTSD
Interventions
Accelerated, Multi-Couple Group CBCT for PTSD
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Killeen, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

Development of a Couple-based Mindfulness Intervention for Chronic Pain

NCT02316288
View directory record Official record
Conditions
Chronic Pain
Interventions
Mindfulness and Acceptance Therapy, Health Education
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
21 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

Couple Interaction and Health Behaviors

NCT03163082
View directory record Official record
Conditions
Couples, Relationship, Marital
Interventions
Cognitive Intervention, Behavioral Intervention, Interpretation Bias, Evaluative Conditioning
Other · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Phase 2 Interventional Results available

Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin

NCT05207436
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Relational Problems
Interventions
Oxytocin nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
Drug · Behavioral
Lead sponsor
San Diego Veterans Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners

NCT05867680
View directory record Official record
Conditions
Anxiety Disorders Generalized, Depression
Interventions
Online Mothers and Babies Course (eMB)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 25, 2026, 8:39 AM EDT
Recruiting Not applicable Interventional

The Improving Sleep in African American Couples Study (ISAAC)

NCT07447284
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
CPAP Training and Education, Virtual Disease Support Group Sessions, Couple CPAP Training and Education, Couples Virtual OSA Support Group Sessions, CPAP Tele-monitoring and Feedback, Couples' Cognitive Behavioral Therapy
Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
30 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Cleveland, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional Results available

Uniting Couples in the Treatment of Binge-Eating Disorder

NCT03784820
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
UNITE, CBT-E
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SAVA Syndemic Risk Reduction for African American Couples

NCT04766697
View directory record Official record
Conditions
SAVA
Interventions
Risk-Reduction Sessions
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 49 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Phase 3 Interventional

Individual PE vs Couples' CBT for Combat-Related Posttraumatic Stress Disorder

NCT02336971
View directory record Official record
Conditions
PTSD, Marital Relationship
Interventions
CBCT for PTSD, Prolonged Exposure
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
3
States / cities
Fort Hood, Texas • Fort Sam Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Risk Reduction Program in Preventing the Transmission of HIV and Sexually Transmitted Diseases in African-American Couples

NCT00644163
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Disease
Interventions
Eban HIV/STD Risk Reduction Intervention, Eban Health Promotion Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,070 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
4
States / cities
Los Angeles, California • Atlanta, Georgia • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2014 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional Results available

Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing

NCT04241094
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Loved one assisted treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
Decatur, Georgia • Ann Arbor, Michigan • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Phase 1Phase 2 Interventional

Fathers for Change for Men With Co-occurring Domestic Violence and Substance Abuse

NCT01385553
View directory record Official record
Conditions
Domestic Violence, Substance Abuse, Parenting
Interventions
Fathers for Change, Individual Drug Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Phase 1 Interventional Results available

Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress Disorder

NCT00946322
View directory record Official record
Conditions
Alcohol-related Disorders, Post-traumatic Stress Disorder
Interventions
Couple-Based Treatment for Alcohol Use Disorders and PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strength at Home Couples Program (PTSD-Focused Relationship Enhancement Therapy for Returning Veterans)

NCT00827879
View directory record Official record
Conditions
Aggression, Post Traumatic Stress Disorders
Interventions
Strength at Home Couples Group, Supportive Group Therapy
Behavioral
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional Results available

Coping Together After Breast Cancer

NCT03930797
View directory record Official record
Conditions
Breast Cancer
Interventions
Intimacy Enhancement, Living Healthy Together
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Sep 25, 2026, 8:39 AM EDT
Terminated Not applicable Interventional Results available

Improving Erectile Function and Quality of Life After Prostate Cancer Treatment

NCT01996852
View directory record Official record
Conditions
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Simple Prostatectomy, Erectile Dysfunction
Interventions
Cognitive-behavioral Meetings, sildenafil citrate, Vacuum Constriction Device
Behavioral · Drug · Device
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
21 Years and older · Male only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Sep 25, 2026, 8:39 AM EDT
Recruiting Not applicable Interventional

Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples

NCT06047691
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Abbreviated, Intensive, Multi-Couple Group Cognitive-Behavioral Conjoint Therapy for PTSD, Prevention and Relationship Education Program
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

Behavioral Interventions to Prevent or Delay Dementia

NCT02265757
View directory record Official record
Conditions
Mild Cognitive Impairment, Memory Disorders, Mild Dementia, Impaired Cognition, Mild Cognitive Disorder, Amnestic Disorder, Dementia and Amnestic Conditions, Poor Short-term Memory, Memory Impairment
Interventions
Cognitive Rehabilitation, Computer Brain Fitness Training, Support Group (patient and partner), Wellness Education, Physical Exercise
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

UCAN: Uniting Couples in the Treatment of Anorexia Nervosa

NCT00928109
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
CBCT, Family Supportive Therapy
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2012 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

Adapting Alcohol Behavioral Couple Therapy for Service Members in Post-Deployment

NCT03589521
View directory record Official record
Conditions
Alcohol Abuse
Interventions
ABCT_Military
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional Results available

Cognitive-Behavioral Conjoint Therapy (CBCT) Project

NCT02720016
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
CBCT-Home Based (CBCT-HB), CBCT-Office Based (CBCT-OB), PTSD Family Education (PFE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2022 · Synced Sep 25, 2026, 8:39 AM EDT
Completed Not applicable Interventional

UCAN2: Uniting Couples in the Treatment of Anorexia Nervosa

NCT01740752
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
UCAN+CBT, CBT
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Sep 25, 2026, 8:39 AM EDT