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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:35 PM EDT

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Showing 1–24 of 131 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Couples Therapy Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders

NCT01690494
View directory record Official record
Conditions
Sexually Transmitted Diseases, Unsafe Sex, Substance-Related Disorders
Interventions
PACT, TAU
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 22, 2026, 2:35 PM EDT
Not listed Not applicable Interventional

Assessing Psychotherapy Outcome With Feedback

NCT02023736
View directory record Official record
Conditions
Individual Psychiatric Disorder, Couple Dysfunction, Family Dysfunction
Interventions
Systemic Therapy Inventory of Change (STIC), Treatment as Usual
Other
Lead sponsor
The Family Institute at Northwestern University
Other
Eligibility
12 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional Results available

Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19

NCT05419128
View directory record Official record
Conditions
Alcohol Use Disorder, Family Members, Behavior, Addictive
Interventions
PartnerCHESS, ACHESS
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 22, 2026, 2:35 PM EDT
Recruiting Phase 2 Interventional

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

NCT06194851
View directory record Official record
Conditions
Post-Traumatic Stress Disorder (PTSD)
Interventions
Oxytocin nasal spray, Saline nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)

NCT02043015
View directory record Official record
Conditions
HIV
Interventions
Condom choices, Condom-compatible lubricant choices, Couples HIV counseling and testing (CVCT), Pre-exposure prophylaxis with FTC/TDF, Staff and provider MSM and LGBT sensitization training, HIV Testing and Risk-reduction counseling, Linkage to care
Behavioral · Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional Results available

Nueva Vida Intervention for Latina Breast Cancer Survivors and Caregivers

NCT02222337
View directory record Official record
Conditions
Quality of Life, Breast Cancer
Interventions
Nueva Vida Intervention
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
Up to 85 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
San Jose, California • Washington D.C., District of Columbia • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Phase 2 Interventional

Multimedia Training for Family Caregivers in Use of Touch and Massage in Supportive Cancer Care

NCT00632398
View directory record Official record
Conditions
Cancer
Interventions
Attention control (reading), Touch, Caring and Cancer DVD program
Behavioral
Lead sponsor
Collinge and Associates, Inc.
Other
Eligibility
21 Years to 120 Years
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
3
States / cities
Kittery, Maine • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Oct 22, 2026, 2:35 PM EDT
Terminated No phase listed Observational

Split Cohort Trial Comparing IVF Outcomes After the Use of Testicular vs. Ejaculated Sperm for ICSI

NCT03483298
View directory record Official record
Conditions
Infertility
Interventions
ICSI
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
7 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Couple Interaction and Health Behaviors

NCT03163082
View directory record Official record
Conditions
Couples, Relationship, Marital
Interventions
Cognitive Intervention, Behavioral Intervention, Interpretation Bias, Evaluative Conditioning
Other · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer

NCT01982058
View directory record Official record
Conditions
Prostate Cancer, Sexual Dysfunction and Infertility, Sexuality
Interventions
communication intervention, counseling intervention, nutrition intervention, questionnaire administration
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
483 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
6
States / cities
New Brunswick, New Jersey • Newark, New Jersey • Whippany, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients

NCT03811028
View directory record Official record
Conditions
Sanfilippo Syndrome Type A (MPS IIIA)
Interventions
SOBI003
Drug
Lead sponsor
Swedish Orphan Biovitrum
Industry
Eligibility
18 Months to 78 Months
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Oakland, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2022 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Behavioral Interventions to Prevent or Delay Dementia

NCT02265757
View directory record Official record
Conditions
Mild Cognitive Impairment, Memory Disorders, Mild Dementia, Impaired Cognition, Mild Cognitive Disorder, Amnestic Disorder, Dementia and Amnestic Conditions, Poor Short-term Memory, Memory Impairment
Interventions
Cognitive Rehabilitation, Computer Brain Fitness Training, Support Group (patient and partner), Wellness Education, Physical Exercise
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 22, 2026, 2:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

HealthyTogether: RCT of a Dyadic Weight Management Intervention

NCT06619041
View directory record Official record
Conditions
Obesity, Overweight
Interventions
HealthyTogether
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Study to Understand Pain Experiences in Relationships

NCT02859545
View directory record Official record
Conditions
Chronic Pain
Interventions
Emotional Validation Training for Romantic Partners, Chronic Pain Education Training for Romantic Partners
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strength at Home Couples Program (PTSD-Focused Relationship Enhancement Therapy for Returning Veterans)

NCT00827879
View directory record Official record
Conditions
Aggression, Post Traumatic Stress Disorders
Interventions
Strength at Home Couples Group, Supportive Group Therapy
Behavioral
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional Results available

FitMi Plus Home Therapy for Stroke Patients

NCT03935425
View directory record Official record
Conditions
Cerebral Stroke
Interventions
FitMi Plus, FitMi Basic
Device
Lead sponsor
Flint Rehabilitation Devices, LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Downey, California • Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Couple-Focused Intervention for Breast Cancer Patients

NCT00940277
View directory record Official record
Conditions
Breast Cancer
Interventions
Group Counseling
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
611 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
5
States / cities
Newark, Delaware • Voorhees Township, New Jersey • Bryn Mawr, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Treatment for Relationships and Safety Together

NCT04816149
View directory record Official record
Conditions
Suicide, Interpersonal Relations
Interventions
VA Standard Suicide Intervention, Treatment for Relationships and Safety Together (TR&ST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 22, 2026, 2:35 PM EDT
Enrolling by invitation Phase 2 Interventional

Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk

NCT06649929
View directory record Official record
Conditions
Sleep Apnea, Sleep Disturbance
Interventions
Couples-based treatment- Patient, Couples-based treatment- Partner, Information control- Patient, Information control- Partner
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
35 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Tuscon, Arizona • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 22, 2026, 2:35 PM EDT
Recruiting Not applicable Interventional

TRAIL Study: Feasibility and Pilot

NCT06220656
View directory record Official record
Conditions
Thyroid Nodule, Thyroid Neoplasms, Thyroid Cancer
Interventions
Biopsy, Active Monitoring
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Intensive Weekend Retreat Multi-Couple Group Therapy for PTSD

NCT03158558
View directory record Official record
Conditions
PTSD
Interventions
Accelerated, Multi-Couple Group CBCT for PTSD
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Killeen, Texas
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Early Phase 1 Interventional

Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury

NCT03643770
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Upper extremity training/Armeo Spring
Combination Product
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 22, 2026, 2:35 PM EDT
Completed Not applicable Interventional Results available

Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury

NCT03267212
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Non-invasive ventilation(NIV), Sham Non-invasive ventilation(NIV), Functional Electrical Stimulation Row Training (FESRT)
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Oct 22, 2026, 2:35 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Acoustic Neuromodulation (ANM) for Youth With Anxiety Disorders

NCT02572973
View directory record Official record
Conditions
Separation Anxiety Disorder, Generalized Anxiety Disorder, Social Phobia
Interventions
Acoustic Neuromodulation (ANM)
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
7 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 22, 2026, 2:35 PM EDT