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ClinicalTrials.gov public records Last synced Oct 25, 2026, 11:58 PM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Couples counseling Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Expanding the Potential of Couples HIV Testing: Adjunct Modules to Reduce Drug Use Among Vulnerable Male Couples

NCT05000866
View directory record Official record
Conditions
Substance Use, HIV Infections
Interventions
Communication skills training video, Drug use module
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
17 Years to 29 Years · Male only
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Ann Arbor, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 25, 2026, 11:58 PM EDT
Not listed Not applicable Interventional

Couples Coping With Alzheimer's Disease

NCT00438724
View directory record Official record
Conditions
Aging, Alzheimer Disease, Dementia
Interventions
Information, counseling and support
Behavioral
Lead sponsor
Alzheimer's Association
Other
Eligibility
21 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 20, 2007 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Phase 2Phase 3 Interventional

Treating the Partners of Drug Using Pregnant Women: Stage II

NCT00496990
View directory record Official record
Conditions
Drug Addiction
Interventions
Enhanced care, control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 60 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Phase 2 Interventional

HIV Prevention Intervention for Couples

NCT00325585
View directory record Official record
Conditions
Acquired Immunodeficiency Syndrome
Interventions
Couples HIV counseling and testing, Women's relationship-focused HIV counseling and testing
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2013 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Phase 1Phase 2 Interventional

Fathers for Change for Men With Co-occurring Domestic Violence and Substance Abuse

NCT01385553
View directory record Official record
Conditions
Domestic Violence, Substance Abuse, Parenting
Interventions
Fathers for Change, Individual Drug Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 19, 2014 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Incorporating Financial Incentives to Increase Smoking Cessation Among Asian Americans Residing in New York City

NCT03397511
View directory record Official record
Conditions
Smoking Cessation, Smoking, Cigarette
Interventions
Financial Incentives
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2019 · Synced Oct 25, 2026, 11:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Safer Conception Intervention for HIV-1 Serodiscordant Couples

NCT03030768
View directory record Official record
Conditions
HIV Seropositivity, Pregnancy, High-Risk
Interventions
PrEP, Counseling on timed condomless sex, ART and PrEP adherence
Drug · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 49 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 25, 2026, 11:58 PM EDT
Enrolling by invitation Not applicable Interventional

Evaluating the Efficacy of Annual CHTC Retesting Among Male Couples at High Risk of HIV Infection

NCT05833074
View directory record Official record
Conditions
HIV Infections
Interventions
Couples HIV testing and counseling, Individual HIV testing and counseling
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
17 Years to 65 Years · Male only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Ann Arbor, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 25, 2026, 11:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

NCT06307977
View directory record Official record
Conditions
Substance Use, HIV Infections
Interventions
Couples Health Project
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
3
States / cities
Detroit, Michigan • New York, New York • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Phase 2 Interventional

Couples Therapy for Alcoholic Patients

NCT01659957
View directory record Official record
Conditions
Alcoholism
Interventions
Group Couples Counseling, One-on-One Couples Counseling
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years to 65 Years
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Couples Miscarriage Healing Project:Randomized Trial

NCT00194844
View directory record Official record
Conditions
Miscarriage, Grief, Pregnancy Loss
Interventions
Nurse Caring, Self Caring, Combined Caring
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
682 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 18, 2008 · Synced Oct 25, 2026, 11:58 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Two-Session Couples Class to Improve Relationship Health

NCT05026372
View directory record Official record
Conditions
Stress
Interventions
Mindfulness Compassion (MC), Mindfulness Gratitude (MG), Mindfulness Value-Based Living (MV)
Behavioral
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Huntsville, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Addressing Substance Use Through CVCT

NCT03125915
View directory record Official record
Conditions
Sex, Unsafe, Drug Use
Interventions
Communication skills training video, substance use module, Couples HIV Testing and Counseling
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2021 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

We Prevent: A Dyadic Approach to HIV Prevention and Care Among Young Male Couples

NCT03551938
View directory record Official record
Conditions
HIV/AIDS
Interventions
Relationship skills session for YMSM partnered-individuals and couples
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
15 Years to 24 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 25, 2026, 11:58 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

A Couples-based Intervention for Transgender Women and Their Partners

NCT04067661
View directory record Official record
Conditions
HIV Infections, HIV Primary Infection
Interventions
CHIP, Control
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)

NCT02043015
View directory record Official record
Conditions
HIV
Interventions
Condom choices, Condom-compatible lubricant choices, Couples HIV counseling and testing (CVCT), Pre-exposure prophylaxis with FTC/TDF, Staff and provider MSM and LGBT sensitization training, HIV Testing and Risk-reduction counseling, Linkage to care
Behavioral · Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Sexual Safety: Couples' Communication and HIV Testing Among YMSM

NCT04289116
View directory record Official record
Conditions
HIV/AIDS, HIV Infections
Interventions
We Test, IHTC
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Detroit, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Results available

Taking Care of Us: A Dyadic Intervention for Heart Failure Couples

NCT04737759
View directory record Official record
Conditions
Heart Failure
Interventions
Taking Care of Us, SUPPORT
Behavioral · Other
Lead sponsor
Boston College
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

En Pareja: A Latino Couples Intervention to Help Expectant Fathers Quit Smoking

NCT01040949
View directory record Official record
Conditions
Smoking Cessation
Interventions
couple-based counseling for smoking cessation plus self-help smoking cessation guide, Guia -a self help smoking cessation guide
Behavioral
Lead sponsor
Duke University
Other
Eligibility
16 Years and older
Enrollment
705 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Couple-Based Physical Activity Intervention

NCT06073951
View directory record Official record
Conditions
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Interventions
Best Practice, Exercise Counseling, Exercise Intervention, Medical Device Usage and Evaluation, Physical Performance Testing, Questionnaire Administration
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Couples Health Project: Couples-based Intervention to Reduce Drug Use and HIV Transmission Risk

NCT03386110
View directory record Official record
Conditions
Risk Behavior, Drug Use, Sex, Anal
Interventions
Couples Health Project (CHP), Education
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project Nexus: Providing Online Counseling for Home-Based HIV Testing

NCT02335138
View directory record Official record
Conditions
Couples
Interventions
Couples HIV Testing and Counseling (CHTC, CVCT), at-home test kit
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Male only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Oct 25, 2026, 11:58 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Study of Time to Pregnancy in Normal Fertility

NCT00161395
View directory record Official record
Conditions
Fertility, Pregnancy
Interventions
Instruction in the Creighton Model Fertility Care System, Preconception advice
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 16, 2008 · Synced Oct 25, 2026, 11:58 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer

NCT07664579
View directory record Official record
Conditions
Anatomic Stage IV Breast Cancer AJCC v8, Glioblastoma, Lung Carcinoma, Malignant Solid Neoplasm, Metastatic Breast Carcinoma
Interventions
Non-Interventional Study
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 25, 2026, 11:58 PM EDT