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ClinicalTrials.gov public records Last synced Oct 3, 2026, 5:40 PM EDT

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Showing 25–39 of 39 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cranial Electrotherapy Stimulation Clear all
Recruiting Not applicable Interventional

Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders

NCT07017322
View directory record Official record
Conditions
Eating Disorders, Anxiety
Interventions
Alpha-Stim AID
Device
Lead sponsor
Rogers Behavioral Health
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Oconomowoc, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Cranial Electrotherapy Stimulation (CES) on Brain Function, Brain Chemistry and Mood

NCT01860677
View directory record Official record
Conditions
Mood
Interventions
Fisher Wallace Cranial Stimulator
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
21 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2017 · Synced Oct 3, 2026, 5:40 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Fisher Wallace Neurostimulation & Depression Study

NCT04541563
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Fisher Wallace Cranial Electrotherapy Stimulator Device
Device
Lead sponsor
ProofPilot
Industry
Eligibility
21 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

Cranial Electrotherapy Stimulation in the Treatment of Migraine Headaches

NCT01265797
View directory record Official record
Conditions
Migraine
Interventions
Cranial Electrostimulator, Sham Device
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2015 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional

Combining CES Alpha-Stim and InterX for Optimized Rehabilitation Following Extremity Immobilization

NCT03060122
View directory record Official record
Conditions
Neuropathic Pain
Interventions
NIN, Sham CES, CES
Device
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cranial Electrotherapy Stimulation and Acute Stress

NCT06034496
View directory record Official record
Conditions
Anxiety State
Interventions
Active CES, Sham CES
Device
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 40 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Medford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 3, 2026, 5:40 PM EDT
Terminated Phase 4 Interventional Results available

Cranial Electro Therapy Stimulation in Reducing Perioperative Anxiety

NCT00928772
View directory record Official record
Conditions
Anxiety
Interventions
CRANIAL ELECTROTHERAPY (Alpha Stim) + SHAM MIDAZOLAM, MIDAZOLAM + SHAM ELECTRODES SIMULATING CRANIAL ELECTROTHERAPY, NO SEDATION WITH SHAM CRANIAL ELECTROSTIMULATION AND PLACEBO VERSED
Device · Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
50 Years to 90 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 3, 2026, 5:40 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia

NCT07659366
View directory record Official record
Conditions
Moderate to Severe Insomnia
Interventions
Transcranial alternating current stimulator
Device
Lead sponsor
Nexalin Technology
Industry
Eligibility
22 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 3, 2026, 5:40 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Brain Stimulation & Generalized Anxiety Study

NCT04751864
View directory record Official record
Conditions
Anxiety, Generalized Anxiety Disorder, Generalized Anxiety
Interventions
Cranial Electrotherapy Stimulator (CES) Device
Device
Lead sponsor
ProofPilot
Industry
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 3, 2026, 5:40 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder

NCT03222752
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Cranial Electrotherapy Stimulation, Sham Cranial Electrotherapy Stimulation
Device
Lead sponsor
Electromedical Products International, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Forest, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality and tACS for Performance Enhancement

NCT03636126
View directory record Official record
Conditions
Law Enforcement Officers
Interventions
VR + TACS
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Garland, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Oct 3, 2026, 5:40 PM EDT
Recruiting Not applicable Interventional

Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome

NCT07151248
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Cranial electrical/electrotherapy stimulation (CES), Sham Cranial electrical/electrotherapy stimulation (CES)
Device
Lead sponsor
Emory University
Other
Eligibility
40 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

The Efficacy of Cranial Electrostimulating Therapy for Depression and Anxiety Among Homeless Adults

NCT02732561
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Alpha Stim device, Sham device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional Results available

The Safety and Efficacy of Nexalin Trans-cranial Electrical Stimulation Stimulation for the Treatment of Depression

NCT03277846
View directory record Official record
Conditions
Depression
Interventions
Nexalin Based Trans-Cranial Electrical Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Belle Mead, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Oct 3, 2026, 5:40 PM EDT
Completed Not applicable Interventional

Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS

NCT02263274
View directory record Official record
Conditions
Epilepsy
Interventions
Transcranial Direct Current Stimulation (TDCS)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 3, 2026, 5:40 PM EDT