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ClinicalTrials.gov public records Last synced Oct 29, 2026, 9:24 PM EDT

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Showing 865–888 of 999 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cream Clear all
Completed Phase 2Phase 3 Interventional Results available

Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face

NCT04523961
View directory record Official record
Conditions
Anesthesia, Local, Photodamaged Skin, Topical and Infiltration Anesthetic Toxicity
Interventions
2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion, 7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Case Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment on Healthy Females with Fitzpatrick Skin Types V and VI

NCT06633731
View directory record Official record
Conditions
Skin Smoothness, Radiance, Overall Appearance
Interventions
Biocellulose Mask, Post Procedure Cream, Gentle Cleanser, Facial Moisturizer, sunscreen
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
45 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 3 Interventional Results available

Multicenter Study to Evaluate Safety and Efficacy of WC3011 (Estradiol Vaginal Cream) in Postmenopausal Women

NCT01816139
View directory record Official record
Conditions
Vulvovaginal Atrophy
Interventions
Vehicle, WC3011 Estradiol Vaginal Cream
Drug
Lead sponsor
Warner Chilcott
Industry
Eligibility
35 Years and older · Female only
Enrollment
576 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
48
States / cities
Huntsville, Alabama • Mobile, Alabama • Phoenix, Arizona + 38 more
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 29, 2026, 9:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Remote Cardiac Ischemic Preconditioning

NCT06390358
View directory record Official record
Conditions
Cardiac Function and Preconditioning
Interventions
Tefillin
Other
Lead sponsor
Jack Rubinstein
Other
Eligibility
18 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Oct 29, 2026, 9:24 PM EDT
Recruiting Phase 4 Interventional

Obtaining Descriptive Classifications of Pruritus and Assessing Change in Pruritus Over Time in Atopic Dermatitis Patients Using Topical Roflumilast Cream.

NCT07560618
View directory record Official record
Conditions
ITCH, Atopic Dermatitis
Interventions
Roflumilast Cream 0.15%
Drug
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
12 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 3 Interventional Results available

A Long-Term Safety and Efficacy Study AGN-19920 in Patients With Persistent Erythema Associated With Rosacea

NCT02095158
View directory record Official record
Conditions
Erythema, Rosacea
Interventions
Oxymetazoline HCL Cream 1.0%
Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 1 Interventional

Topical Application of MyoRx (Omega 3 Fatty Acids Containing) Cream

NCT00690625
View directory record Official record
Conditions
Myofacial Pain
Interventions
MyoRx Cream (6% Omega 3 Fatty Acid), Placebo cream, no Omega 3 fatty acid
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 9, 2008 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 2 Interventional Results available

Topical Capsaicin for Cyclical Vomiting

NCT03223350
View directory record Official record
Conditions
Cyclical Vomiting
Interventions
Capsaicin 0.1% Cream, Placebos
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Dose Escalating Study to Evaluate the Safety and Efficacy of CB-03-01 Cream in Subjects With Facial Acne Vulgaris

NCT01631474
View directory record Official record
Conditions
Acne Vulgaris
Interventions
CB-03-01, Vehicle
Drug
Lead sponsor
Intrepid Therapeutics, Inc.
Industry
Eligibility
12 Years and older
Enrollment
363 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
13
States / cities
Los Angeles, California • San Diego, California • Sanford, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Treatments Used for White Spot Lesions After Orthodontic Treatment.

NCT01059058
View directory record Official record
Conditions
Tooth Demineralization
Interventions
MI Paste Plus, PreviDent Fluoride Varnish, Normal Home Care
Procedure
Lead sponsor
University of Washington
Other
Eligibility
12 Years to 20 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Assessment of the Human Systemic Absorption of Sunscreen Ingredients

NCT03582215
View directory record Official record
Conditions
Systemic Exposure to Sunscreen Ingredients
Interventions
Part 1: Cream, Part 1: Lotion, Part 1: Spray 1, Part 1: Spray 2, Part 2: Lotion, Part 2: Aerosol Spray, Part 2: Nonaerosol Spray, Part 2: Pump Spray
Drug
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
18 Years to 60 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 1 Interventional Results available

Clinical Equivalence of Two Butenafine Hydrochloride 1% Creams in Patients With Interdigital Tinea Pedis

NCT00835510
View directory record Official record
Conditions
Tinea Pedis
Interventions
Butenafine cream 1% manufactured by Taro, Lotrimin Ultra (butenafine) 1%, Butenafine Vehicle manufactured by Taro
Drug
Lead sponsor
Sun Pharmaceutical Industries, Inc.
Industry
Eligibility
12 Years and older
Enrollment
548 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
16
States / cities
Burbank, California • San Diego, California • Miami, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infants

NCT01827358
View directory record Official record
Conditions
Staphylococcal Infection
Interventions
Mupirocin calcium
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Up to 24 Months
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
6
States / cities
Atlanta, Georgia • Baltimore, Maryland • Kansas City, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Pediatric Taste Test Study of Cefdinir (Omnicef) Versus Amoxicillin Antibiotic Suspension Medications

NCT00644891
View directory record Official record
Conditions
Healthy
Interventions
cefdinir (Omnicef), amoxicillin
Drug
Lead sponsor
Abbott
Industry
Eligibility
4 Years to 8 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
3
States / cities
Scottsdale, Arizona • St. Petersburg, Florida • Miamiville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2008 · Synced Oct 29, 2026, 9:24 PM EDT
Active, not recruiting Phase 3 Interventional

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis

NCT06832618
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Ruxolitinib, Vehicle Cream
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
6 Years to 17 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Denver, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 29, 2026, 9:24 PM EDT
Withdrawn Not applicable Interventional

Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia

NCT03390049
View directory record Official record
Conditions
Vestibulodynia
Interventions
Fractional CO2 Laser Treatment, Sham Laser Treatment
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Oct 29, 2026, 9:24 PM EDT
Not listed Phase 2 Interventional

Assessment of Suppression of Cutaneous Allergic Responses and Pruritis by Topical Minocycline

NCT04202263
View directory record Official record
Conditions
Allergic Rhinitis, Asthma
Interventions
Minocycline Topical, Placebos
Drug
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 2 Interventional Results available

Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis

NCT05186805
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Tapinarof cream, 1%
Drug
Lead sponsor
Organon and Co
Industry
Eligibility
2 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
9
States / cities
Thousand Oaks, California • Centennial, Colorado • Coral Gables, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 29, 2026, 9:24 PM EDT
Recruiting Early Phase 1 Interventional

Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain

NCT07260656
View directory record Official record
Conditions
Diabetic Neuropathies, Painful, Diabetic Foot, Diabetic Peripheral Neuropathy
Interventions
Capsaicin Palmitate, Placebo
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
25 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 29, 2026, 9:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fiber Soda on Postprandial Risk Factors

NCT07882264
View directory record Official record
Conditions
Healthy Participants
Interventions
Prebiotic soda followed by high-fat meal, Control beverage followed by high-fat meal
Other
Lead sponsor
Ball State University
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Muncie, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Phthalate and Bisphenol Exposure During Minipuberty

NCT05864209
View directory record Official record
Conditions
Phthalate Exposure, Bisphenol Exposure
Interventions
Phthalate- and Bisphenol-free Baby Products, Cloth Diapers, Conventional Disposable Diapers, Conventional Baby Products
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate the Impact of aKwa Skincare System on Skin Health

NCT05476406
View directory record Official record
Conditions
Sin Health, Skin Hydration, Skin Wrinkles, Skin Porphyrins, Facial Skin Red Spots, Facial Skin Red Vasculature
Interventions
äKwä skincare system products, competitor products (control)
Other
Lead sponsor
4Life Research, LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Sandy City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 2 Interventional Results available

Topical Ruxolitinib Evaluation in Chronic Hand Eczema

NCT05906628
View directory record Official record
Conditions
Hand Eczema
Interventions
Ruxolitinib cream, Vehicle
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
23
States / cities
Phoenix, Arizona • Fountain Valley, California • Huntington Beach, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 29, 2026, 9:24 PM EDT
Completed Phase 1 Interventional

A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis

NCT03257644
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Ruxolitinib phosphate cream
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
2 Years to 17 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
23
States / cities
Hoover, Alabama • Gilbert, Arizona • Little Rock, Arkansas + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 29, 2026, 9:24 PM EDT