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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Crisis Prevention Arm Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care

NCT04450966
View directory record Official record
Conditions
Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
Interventions
Computer-facilitated Screening and Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 17 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Itasca, Illinois • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Recruiting Not applicable Interventional

Written Exposure Therapy for Suicide Prevention

NCT05878795
View directory record Official record
Conditions
Suicide, Attempted, Suicide Threat
Interventions
WET-SP, TAU
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Recruiting Not applicable Interventional

Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A

NCT06223867
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Self Harm
Interventions
Jaspr App + JAH, ETAU
Device · Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
670 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engaging Seronegative Youth to Optimize HIV Prevention Continuum

NCT03134833
View directory record Official record
Conditions
HIV, Mental Health, Substance Use, STI
Interventions
Automated Messaging & Monitoring, Peer Support, Coaching
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
1,478 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 4, 2022 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Psychosis: Early Detection, Intervention and Prevention

NCT01597141
View directory record Official record
Conditions
Prodromal Schizophrenia, Psychotic Disorders, Severe Bipolar Disorder With Psychotic Features, Severe Major Depression With Psychotic Features
Interventions
Family-aided Assertive Community Treatment, Enhanced standard treatment
Behavioral
Lead sponsor
MaineHealth
Other
Eligibility
12 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Close to Home Program in California

NCT05206994
View directory record Official record
Conditions
Sexual Violence, Sexual Assault, Adolescent Behavior
Interventions
Close to Home
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
14 Years to 24 Years
Enrollment
953 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Enrolling by invitation Not applicable Interventional

Advancing Student Suicide Interventions With Scalable Technologies

NCT07211373
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Self-Harm
Interventions
Jaspr, Behavioral support
Device · Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Phase 2 Interventional

A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD)

NCT05075824
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Crovalimab, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
12 Years to 55 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Detroit, Michigan • Madison, Mississippi • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Recruiting Not applicable Interventional

Store Safely: Rural Firearm Injury Prevention for Families

NCT06719713
View directory record Official record
Conditions
Firearm Injury
Interventions
Store Safely
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • Negaunee, Michigan
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Not yet recruiting Phase 3 Interventional

A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis

NCT06989567
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
L-citrulline, Placebo
Drug · Other
Lead sponsor
Asklepion Pharmaceuticals, LLC
Industry
Eligibility
6 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Coral Gables, Florida • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 2, 2026, 10:48 PM EDT
Recruiting Phase 2Phase 3 Interventional

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

NCT05696691
View directory record Official record
Conditions
Suicide
Interventions
Ketamine Hydrochloride, Crisis Response Plan
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional

CAMS Relational Agent System (CAMS-RAS) for Suicide Prevention

NCT03584386
View directory record Official record
Conditions
Suicide
Interventions
V-CAMS (aka Jaspr)
Device
Lead sponsor
Evidence-Based Practice Institute, Seattle, WA
Industry
Eligibility
18 Years and older
Enrollment
357 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Sep 2, 2026, 10:48 PM EDT
Not yet recruiting Not applicable Interventional

TeleABA for Hospitalized Adolescents and Young Adults With Autism Spectrum Disorder

NCT07701915
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD)
Interventions
Standard Hospital Care, Telehealth Applied Behavior Analysis (TeleABA)
Behavioral
Lead sponsor
Caring Technologies, Inc.
Industry
Eligibility
12 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Neptune City, New Jersey • Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Behavioral and Psychological Symptoms of Dementia: Family Caregivers (Aim 1)

NCT04481568
View directory record Official record
Conditions
Alzheimer's Disease and Related Dementias
Interventions
PES-4-BPSD Model, The attention control condition
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
65 Years and older
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Glen Oaks, New York • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional

Family-Based Treatment for Parental Substance Abuse and Child Maltreatment

NCT01656837
View directory record Official record
Conditions
Substance Abuse, Child Abuse, Child Neglect
Interventions
Comprehensive Community Treatment, MST-BSF
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
New Britain, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional

Screening, Brief Intervention and Referral to Treatment for Substance Abuse in Mental Health Treatment Settings

NCT01883791
View directory record Official record
Conditions
Substance Use Disorders, Mental Illness
Interventions
SBIRT, Health Education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
1,080 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Los Angeles, California • Oxnard, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2018 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional

A Crisis Prevention Program for Youth With Autism

NCT05681143
View directory record Official record
Conditions
Autism Spectrum Disorder, Behavior Problem
Interventions
Crisis Prevention Arm, Control
Other
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
3 Years to 17 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Sep 2, 2026, 10:48 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Crisis Response Planning in Military Personnel With Mild Traumatic Brain Injury

NCT07327567
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Suicide Prevention, Suicide Risk | Patient, Suicide Risk, Suicide Risk Factor
Interventions
Crisis Response Planning
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 2, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Preventing Risky Drinking in Veterans Treated With Prescription Opioids

NCT02709317
View directory record Official record
Conditions
Pain, Opiates, Alcohol Drinking
Interventions
Prevention Intervention, Brief Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 88 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
3
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Sep 2, 2026, 10:48 PM EDT
Recruiting Not applicable Interventional

Project Safe Guard-Trauma

NCT06876740
View directory record Official record
Conditions
PTSD, Firearm Injury, Suicide Prevention, Firearm Safety
Interventions
Project Safe Guard - Trauma, Project Safe Guard
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Sep 2, 2026, 10:48 PM EDT