Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 6, 2026, 11:39 PM EDT

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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Conditions
Neurocognitive Disorders
Interventions
Brain HQ Cognitive Modules
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
65 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Iowa Healthy and Active Minds Study

NCT01165463
Conditions
Visual Processing Speed
Interventions
SOPT basic training, Crossword Puzzles, SOPT booster training
Behavioral
Lead sponsor
Fredric D Wolinsky
Other
Eligibility
50 Years and older
Enrollment
681 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Clinical High Risk for Psychosis
Interventions
Targeted Cognitive Training, Computer Games
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
15 Years to 30 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Improving Mood in Assisted Living Settings

NCT01763216
Conditions
Depressive Symptoms, Clinical Depression
Interventions
Road Tour, Boatload of Crosswords
Other
Lead sponsor
Marianne Smith
Other
Eligibility
55 Years and older
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
32
States / cities
Amana, Iowa • Bettendorf, Iowa • Carlisle, Iowa + 17 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intervention Comparative Effectiveness for Adult Cognitive Training

NCT03141281
Conditions
Cognitive Aging
Interventions
BrainHQ, Rise of Nations, IADL Training, Active Control
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
65 Years and older
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Cognitive Impairment
Interventions
Cognitive Rehabilitation, Brain Health Education Program
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Executive Dysfunction, Cognitive Impairment
Interventions
ASCEND-I
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
30 Years to 89 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Mental Training for Adults With Mild Cognitive Impairment

NCT03895346
Conditions
Mild Cognitive Impairment, Aging
Interventions
Mindfulness, Brain Games and Puzzles
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 90 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure NYHA Class I
Interventions
Computerized Cognitive Training with Brain HQ, Computerized Crossword Puzzles
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Results available

Cognitive Fitness for Depression in Older Adults

NCT04790630
Conditions
Depression Mild, Depressive Disorder, Major, Mild Cognitive Impairment
Interventions
Computerized Cognitive Remediation of Executive Functioning (CCR-EF), Active Control
Other
Lead sponsor
UConn Health
Other
Eligibility
60 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Mild Cognitive Impairment (MCI), Cognitive Training
Interventions
Cognitive Training
Other
Lead sponsor
Columbia University
Other
Eligibility
55 Years to 89 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
4
States / cities
Miami, Florida • New York, New York • Durham, North Carolina + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Cognitive Abilities With Comprehensive Training

NCT02367898
Conditions
Cognitive Abilities
Interventions
Lumosity Cognitive Training, Crossword Puzzles
Other
Lead sponsor
Lumos Labs, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
11,470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Francisco, California
Conditions
Mild Cognitive Impairment
Interventions
Multi-domain cognitive training, Cross-word puzzle training
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
65 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Stanford, California
Terminated Not applicable Interventional Results available

Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients

NCT02864940
Conditions
Ruptured Aneurysm, Memory Deficits, Subarachnoid Hemorrhage
Interventions
Lumosity, Crossword puzzle
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Mild Cognitive Impairment, Memory Disorders, Memory Impairment, Cognitive Impairment, Cognitive Disorder, Cognitive Decline
Interventions
Computerized Cognitive Training, Crossword Puzzles
Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
55 Years to 95 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
New York, New York • Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Engagement and Aging Mind

NCT05924490
Conditions
Age-related Cognitive Decline
Interventions
Real-time strategy-based videogame training, Semantic Knowledge training
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Results available

Computerized Cognitive Training in Breast Cancer Survivors

NCT05570604
Conditions
Breast Cancer, Cognitive Change, Cognitive Impairment, Quality of Life
Interventions
Sweep Seeker, Bird Safari, Jewel Diver, Master Gardener, Road Tour, Computerized Crossword Puzzles
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
21 Years and older · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana