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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:57 PM EDT

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Showing 1–24 of 136 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Curcumin Clear all
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β

NCT06470061
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
Interventions
Resveratrol, Quercetin, and Curcumin (RQC), Curcumin
Drug
Lead sponsor
Zaparackas and Knepper LTD
Other
Eligibility
50 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 22, 2026, 4:57 PM EDT
Recruiting Phase 3 Interventional

Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy

NCT02064673
View directory record Official record
Conditions
Prostate Cancer
Interventions
Curcumin, placebo
Drug
Lead sponsor
yair lotan
Other
Eligibility
30 Years to 80 Years · Male only
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 2 Interventional Results available

Trial of Curcumin in Advanced Pancreatic Cancer

NCT00094445
View directory record Official record
Conditions
Pancreatic Neoplasms, Adenocarcinoma
Interventions
Curcumin
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2020 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Effects of Curcumin-containing Toothpaste on Dental Biofilm and Associated Oral Halitosis

NCT04998617
View directory record Official record
Conditions
Halitosis
Interventions
Toothpaste with curcumin, Toothpaste without curcumin
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2023 · Synced Oct 22, 2026, 4:57 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance

NCT06531863
View directory record Official record
Conditions
Mood Disturbance
Interventions
Curcumin, Epigallocatechin Gallate, Placebo
Dietary Supplement · Other
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 22, 2026, 4:57 PM EDT
Not listed Phase 2 Interventional

Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease

NCT01811381
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Curcumin, aerobic yoga, non aerobic yoga, Placebo
Drug · Behavioral · Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 1 Interventional

A "Window Trial" on Curcumin for Invasive Breast Cancer Primary Tumors

NCT03980509
View directory record Official record
Conditions
Breast Cancer
Interventions
Curcumin
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2025 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC)

NCT02978339
View directory record Official record
Conditions
Primary Sclerosing Cholangitis
Interventions
Curcumin
Drug
Lead sponsor
John E. Eaton
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutraceutical Supplement With Vegan Botanicals in Females With Self-Perceived Thinning Hair

NCT05332743
View directory record Official record
Conditions
Hair Thinning
Interventions
Nutrafol Vegan Women's Hair Supplement
Dietary Supplement
Lead sponsor
Nutraceutical Wellness Inc.
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Manhattan Beach, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 22, 2026, 4:57 PM EDT
Withdrawn Phase 2 Interventional

Growth Hormone and Exclusion Diet Therapy in Juvenile Crohn's Disease

NCT01647412
View directory record Official record
Conditions
Crohn's Disease
Interventions
Growth Hormone, Nutraceutical Combination, Exclusion Diet, Placebo Growth Hormone
Drug · Dietary Supplement · Other
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users

NCT04205929
View directory record Official record
Conditions
Bleeding, Implants, Breakthrough Bleeding
Interventions
Placebo, Curcumin
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
15 Years to 45 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 22, 2026, 4:57 PM EDT
Withdrawn Not applicable Interventional

Turmeric as Treatment in Epilepsy

NCT03254680
View directory record Official record
Conditions
Epilepsy, Dravet Syndrome, Lennox-Gastaut Syndrome, Tuberous Sclerosis, Focal Seizures
Interventions
Turmeric
Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
1 Year to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 2 Interventional Results available

18-Month Study of Memory Effects of Curcumin

NCT01383161
View directory record Official record
Conditions
Age-associated Cognitive Impairment, Mild Cognitive Impairment (MCI)
Interventions
Curcumin, Placebo
Drug · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 2 Interventional Results available

Curcumin and Vascular and Cognitive Function in Patients With Chronic Kidney Disease

NCT03223883
View directory record Official record
Conditions
Chronic Kidney Diseases, Cognitive Decline
Interventions
Curcumin, Placebo
Drug · Other
Lead sponsor
Diana Jalal
Other
Eligibility
45 Years to 74 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioenhancing Effects of Black Pepper With Turmeric on Pain Ratings

NCT05206266
View directory record Official record
Conditions
Pain
Interventions
Turmeric, Turmeric+Black Pepper
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

NCT01752868
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Supplement
Dietary Supplement
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 19, 2012 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Curcumin (Diferuloylmethane Derivative) With or Without Bioperine in Patients With Multiple Myeloma

NCT00113841
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Curcumin, Bioperine
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 23, 2011 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Curcumin and Function in Older Adults

NCT03085680
View directory record Official record
Conditions
Older Adults, Physical Function, Cognitive Function
Interventions
Curcumin, microcrystalline cellulose
Drug
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 99 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Safety and Efficacy of RQC for AMD

NCT05062486
View directory record Official record
Conditions
Age-related Macular Degeneration
Interventions
Resveratrol, Quercetin, Curcumin (RQC), Curcumin
Drug
Lead sponsor
Paul A Knepper, MD PhD
Other
Eligibility
50 Years to 90 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 22, 2026, 4:57 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers

NCT03598309
View directory record Official record
Conditions
Lung Diseases, Lung Cancer, Protection Against
Interventions
Curcumin C3 complex®, Lovaza®, Placebo
Drug · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
55 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline

NCT04149639
View directory record Official record
Conditions
Healthy
Interventions
NeuroQ
Dietary Supplement
Lead sponsor
LifeSeasons Inc.
Industry
Eligibility
45 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Studio City, California • Flower Mound, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 22, 2026, 4:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Oral Curcumin Supplementation in Middle-Aged and Older Adults Improves Vascular Function

NCT01968564
View directory record Official record
Conditions
Vascular Aging
Interventions
Placebo pill, High-dose curcumin pill, Low-dose curcumin pill
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
45 Years to 80 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes

NCT04633551
View directory record Official record
Conditions
Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
Interventions
Anti-inflammatory supplement
Dietary Supplement
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Effects of Botanical Microglia Modulators in Gulf War Illness

NCT02909686
View directory record Official record
Conditions
Gulf War Illness
Interventions
Boswellia Serrata, Curcumin, Epimedium, Fisetin, Luteolin, Nettle, Pycnogenol, Reishi Mushroom, Resveratrol, Placebo
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
39 Years to 65 Years · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 22, 2026, 4:57 PM EDT