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ClinicalTrials.gov public records Last synced Sep 11, 2026, 10:33 PM EDT

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Showing 1–4 of 4 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers Results available

IFI16 is a Periodontitis Modulating Protein

NCT03513497
Conditions
Severe Periodontitis, Acute Inflammatory Response
Interventions
Customized acrylic mouthguard
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Variation in Gingival Inflammatory Responses

NCT05968742
Conditions
Gingivitis
Interventions
Abstinence of oral hygiene on select teeth
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Terminated Not applicable Interventional Accepts healthy volunteers

IL29 and IL28B Variants Associated With Periodontal Disease Pathogenesis

NCT02710903
Conditions
Periodontitis
Interventions
Stent-induced biofilm overgrowth
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
25 Years and older
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nocturnal Mouth Guards, SOVA vs. Standard Acrylic Orthotic; Phase IV

NCT02340663
Conditions
Sleep Bruxism, Tooth Wear
Interventions
SOVA Bite Splint, Michigan Bite Splint
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan