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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cytotec Clear all
Terminated No phase listed Observational Accepts healthy volunteers

Labor Protocol Study

NCT04004845
View directory record Official record
Conditions
Vaginal Delivery, Labor, Induced; Birth
Interventions
Cytotec, oxytocin, Cervical Foley Balloon
Drug · Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Sep 10, 2026, 6:16 PM EDT
Not yet recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Impact of Standardization on Outcomes Following Cervical Ripening

NCT07576881
View directory record Official record
Conditions
Pregnancy
Interventions
Cervical Ripening with a double balloon catheter only, Cervical ripening with a double balloon catheter plus misoprostol, Usual-care control group
Device · Combination Product
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 10, 2026, 6:16 PM EDT
Recruiting Phase 4 Interventional

Effect of Misoprostol on Fluid Deficit Volume in Hysteroscopic Myomectomy

NCT07286188
View directory record Official record
Conditions
Fibroids, Uterine, Fluid Deficit, Hysteroscopy / Methods
Interventions
Misoprostol Tabets, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 10, 2026, 6:16 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Mifepristone and Two Doses of Misoprostol for Abortion at 11&12 Weeks

NCT05119439
View directory record Official record
Conditions
Medical Abortion
Interventions
Mifepristone + 2 doses of misoprostol 800 mcg
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
11 Years to 55 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
6
States / cities
Hilo, Hawaii • Honolulu, Hawaii • Saint Paul, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Phase 3 Interventional Results available

Mifepristone for Labor Induction

NCT05097326
View directory record Official record
Conditions
Induced Vaginal Delivery
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 10, 2026, 6:16 PM EDT
Terminated Not applicable Interventional Results available

Cervical Ripening in Postmenopausal Women

NCT02534883
View directory record Official record
Conditions
Stenosis of Cervix
Interventions
Misoprostol, Placebo
Drug
Lead sponsor
St. Louis University
Other
Eligibility
45 Years to 85 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss

NCT02141555
View directory record Official record
Conditions
Spontaneous Abortion in First Trimester
Interventions
Vaginal Misoprostol, Buccal Misoprostol
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Sep 10, 2026, 6:16 PM EDT
Withdrawn Not applicable Interventional

Mifepristone Versus Osmotic Dilators in Conjunction With Misoprostol for Cervical Preparation Prior to D&E at 14-19 Weeks

NCT02679092
View directory record Official record
Conditions
Legally Induced Abortion Without Mention of Complication
Interventions
Misoprostol, Mifepristone, Hygroscopic cervical dilators
Drug · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Phase 2 Interventional

Letrozole and Misoprostol for Early Pregnancy Loss Management

NCT06452719
View directory record Official record
Conditions
Early Pregnancy Loss, Miscarriage in First Trimester, Miscarriage
Interventions
Letrozole, Misoprostol
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Atorvastatin as a Potential Adjunct to Misoprostol for Termination of Pregnancy

NCT05342974
View directory record Official record
Conditions
Abortion Early
Interventions
Atorvastatin, Misoprostol
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 10, 2026, 6:16 PM EDT
Terminated Phase 4 Interventional Results available

Ripening Interventions: Prostaglandins vs EASI Catheter

NCT00383942
View directory record Official record
Conditions
Cesarean Section
Interventions
Misoprostol, Catheter
Drug · Device
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

PROMMO Trial: Oral Misoprostol vs IV Oxytocin

NCT04478942
View directory record Official record
Conditions
Premature Rupture of Membrane, Induction of Labor Affected Fetus / Newborn
Interventions
Misoprostol Oral Product, Intravenous Oxytocin
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Trial of Oral Misoprostol for Labor Augmentation

NCT00906347
View directory record Official record
Conditions
Labor Augmentation
Interventions
Misoprostol, Oxytocin
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2012 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Early Phase 1 Interventional

Early Versus Delayed Artificial Rupture of Membranes (AROM Trial)

NCT04496908
View directory record Official record
Conditions
Induction of Labor Affected Fetus / Newborn
Interventions
amniotomy, Foley Catheter, Misoprostol
Procedure · Device · Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Sep 10, 2026, 6:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 Weeks

NCT01636063
View directory record Official record
Conditions
Induced Abortion, Abortion Techniques, Mifepristone, Misoprostol
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Oral Mifepristone and Buccal Misoprostol Administered Simultaneously for Abortion Through 63 Days Gestation

NCT00330993
View directory record Official record
Conditions
Abortion, Induced
Interventions
mifepristone, misoprostol
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2007 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Letrozole and Misoprostol for Termination of Pregnancy up to 63 Days' Gestation

NCT05207644
View directory record Official record
Conditions
Pregnancy
Interventions
30 mg letrozole followed by 800 mcg misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Comparison of Transcervical Foley Bulb With Vaginal Misoprostol to Vaginal Misoprostol Alone for Induction of Labor

NCT02566005
View directory record Official record
Conditions
Pregnancy
Interventions
misoprostol, Foley bulb
Device
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 26, 2018 · Synced Sep 10, 2026, 6:16 PM EDT
Completed No phase listed Observational

Misoprostol for Spinal Stenosis

NCT04611464
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Low Back Pain
Interventions
Misoprostol
Drug
Lead sponsor
Dallas VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2020 · Synced Sep 10, 2026, 6:16 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

BMI-Associated Labor Induction: A Prospective Trial

NCT04035382
View directory record Official record
Conditions
Labor Induction
Interventions
Labor induction
Procedure
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
Springfield, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Phase 3 Interventional Results available

Efficacy & Safety Study Comparing Misoprostol Vaginal Insert (MVI) Versus Dinoprostone Vaginal Insert (DVI) for Reducing Time to Vaginal Delivery

NCT01127581
View directory record Official record
Conditions
Reducing Time to Vaginal Delivery, Cervical Ripening, Induction of Labor
Interventions
MVI 200, Dinoprostone Vaginal Insert (DVI)
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,358 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
34
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation

NCT03925129
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
high frequency TENS treatment, Sham TENS treatment
Device
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Sep 10, 2026, 6:16 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Period Pills for Menstrual Regulation: A New Reproductive Health Option

NCT07671989
View directory record Official record
Conditions
Menstrual Regulation, Menstrual Health Intervention
Interventions
Mifepristone + Misoprostol
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Oakland, California • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 10, 2026, 6:16 PM EDT
Completed Not applicable Interventional Results available

Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks

NCT01615731
View directory record Official record
Conditions
Abortion, Induced
Interventions
Mifepristone, Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 10, 2026, 6:16 PM EDT