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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Psychological Trauma
Interventions
VR (Virtual reality), D-Cycloserine
Other · Drug
Lead sponsor
United States Army Institute of Surgical Research
Federal
Eligibility
18 Years to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Conditions
Posttraumatic Stress Disorders, PTSD
Interventions
D-cycloserine, Placebo pill, CBT
Drug · Behavioral
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
7 Years to 12 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Obsessive-Compulsive Disorder
Interventions
behavior therapy, D-Cycloserine
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
2
States / cities
Hartford, Connecticut • Boston, Massachusetts
Conditions
Hereditary Spastic Paraplegia
Interventions
D-cycloserine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 6 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Cognitive Enhancing Effects of D-Cycloserine Among Non-Demented Elderly

NCT01361633
Conditions
Treatment, Placebo
Interventions
d-cycloserine, Sugar Pill
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
60 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Smoking Cessation, Harm Reduction
Interventions
d-cycloserine, Juul e-cigarette
Drug · Other
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Conditions
Autistic Disorder
Interventions
D-cycloserine, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
3 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Nicotine Addiction
Interventions
Cycloserine, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Houston, Texas
Conditions
Smokers
Interventions
D-cycloserine, Placebo
Drug
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome

NCT02687165
Conditions
Post Treatment Lyme Syndrome (PTLS), Chronic Pain
Interventions
Milnacipran and D-cycloserine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Stress Disorder, Post Traumatic
Interventions
D-Cycloserine, Alprazolam, Virtual Reality Exposure Therapy, Placebo
Drug · Behavioral
Lead sponsor
Emory University
Other
Eligibility
21 Years to 65 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Posttraumatic Stress Disorder
Interventions
D-Cycloserine, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
New York, New York
Conditions
PTSD
Interventions
CBT + ImRs, CBT + I.E., D-Cycloserine, Placebo, Study Pill
Behavioral · Drug
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Schizophrenia
Interventions
d-cycloserine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Specific Phobia
Interventions
D-cycloserine, Exposure therapy, Placebo
Drug · Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Hartford, Connecticut
Completed Phase 2 Interventional Accepts healthy volunteers Results available

fMRI Study Examining Effects of D-cycloserine in Specific Phobia

NCT00591825
Conditions
Phobias
Interventions
D-cycloserine, Placebo
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Stroke
Interventions
D-cycloserine + distributed treatment, D-cycloserine + condensed treatment, Placebo + distributed treatment, Placebo + condensed treatment
Drug · Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Completed Phase 1Phase 2 Interventional Results available

D-cycloserine and Treatment of Feeding Disorders

NCT01923896
Conditions
Feeding Disorders, Specific Phobia
Interventions
Behavioral Intervention, d-cycloserine (DCS), Placebo
Behavioral · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Months to 6 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Enhancing Panic and Smoking Reduction Treatment With D-Cycloserine

NCT01944423
Conditions
Nicotine Addiction, Panic Attack
Interventions
d-cycloserine, Pill Placebo, Nicotine replacement therapy, Panic and Smoking Reduction Treatment
Drug · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Austin, Texas
Completed Not applicable Interventional Results available

Cognitive Enhancement and Relapse Prevention in Cocaine Addiction

NCT01067846
Conditions
Cocaine Addiction
Interventions
Seromycin (D-cycloserine, DCS), Placebo, Computerized Cognitive Behavioral Therapy
Drug · Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Combat Disorders, Stress Disorders, Post-Traumatic
Interventions
Exposure therapy, D-Cycloserine, Placebo pill
Behavioral · Drug · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obsessive-Compulsive Disorder
Interventions
D-Cycloserine, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
7 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Low Back Pain, Pain
Interventions
D-cycloserine, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Neurotoxicity, Pain, Breast Cancer
Interventions
D-cycloserine, Placebo
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Chicago, Illinois • Madison, Wisconsin