- Conditions
- Prosthetic-joint Infection, Dysbiosis
- Interventions
- Probiotic, Standard of care
- Drug · Other
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • New York, New York
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Showing 1–10
of 10
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Prosthetic-joint Infection
- Interventions
- PLG0206, Placebo
- Drug
- Lead sponsor
- Peptilogics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 15
- States / cities
- Sarasota, Florida • Tamarac, Florida • Shreveport, Louisiana + 12 more
- Conditions
- Total Knee Arthroplasty, Prosthetic-joint Infection, Irrigation
- Interventions
- Methylene Blue 10 MG/ML (intra-articular application), Revision Arthroplasty for PJI (DAIR), Primary Total Knee Arthroplasty
- Drug · Procedure
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Periprosthetic Joint Infection, Antibiotic Suppression
- Interventions
- 6 months of SAT, 12 months of SAT, Indefinite SAT
- Drug
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Periprosthetic Joint Infection (PJI)
- Interventions
- Ultrasound-triggered microbubble destruction with antibiotics
- Drug
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 3
- States / cities
- Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania • Dallas, Texas
- Conditions
- Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
- Interventions
- VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
- Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Periprosthetic Joint Infection
- Interventions
- Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 490 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2032
- U.S. locations
- 2
- States / cities
- Jacksonville, Florida • Rochester, Minnesota
- Conditions
- Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
- Interventions
- TRL1068 (calpurbatug), a human monoclonal antibody, DAIR
- Drug · Procedure
- Lead sponsor
- Trellis Bioscience LLC
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 11
- States / cities
- Gilbert, Arizona • Los Angeles, California • Jacksonville, Florida + 8 more
- Conditions
- Prosthetic Joint Infection
- Interventions
- Bacteriophage, Placebo
- Drug
- Lead sponsor
- Adaptive Phage Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 10
- States / cities
- San Diego, California • Hartford, Connecticut • Idaho Falls, Idaho + 5 more
- Conditions
- Joint Infection
- Interventions
- PLG0206
- Drug
- Lead sponsor
- Peptilogics
- Industry
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 12
- States / cities
- Palo Alto, California • Sarasota, Florida • Baltimore, Maryland + 8 more