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ClinicalTrials.gov public records Last synced Oct 19, 2026, 9:50 PM EDT

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Showing 241–264 of 415 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: DBS Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Adaptive Deep Brain Stimulation for OCD

NCT04281134
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Summit RC+S System, One Month Blinded Discontinuation Period:
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting No phase listed Observational

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

NCT04071847
View directory record Official record
Conditions
Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
Interventions
Deep Brain Stimulation (DBS)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
23
States / cities
Tucson, Arizona • Los Angeles, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed No phase listed Observational

Impact of ART Adherence on HIV Persistence and Inflammation

NCT02797093
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Not applicable Interventional

DBS of the SCC for the Treatment of Medically Refractory CLBP

NCT04085406
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Deep Brain Stimulation of the Subgenus Cingulate Cortex
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 19, 2026, 9:50 PM EDT
Completed Not applicable Interventional

fMRI of Active DBS Stimulation in Epilepsy

NCT03870308
View directory record Official record
Conditions
Epilepsy
Interventions
Functional MRI
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2021 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Methods for Addiction Treatment

NCT07210268
View directory record Official record
Conditions
Nicotine Use Disorder, Substance Use Disorders
Interventions
TI-NDBS, Sham TI-NDBS
Device
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bloomington, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)

NCT00993291
View directory record Official record
Conditions
Parkinson Disease
Interventions
Frequency change to 60 Hz, Frequency change to 130 Hz
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 27, 2012 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Not applicable Interventional

Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease

NCT07398157
View directory record Official record
Conditions
PD - Parkinson's Disease
Interventions
Medtronic Percept Deep Brain Stimulation (cDBS), Medtronic Percept Deep Brain Stimulation (daytime aDBS), Medtronic Percept Deep Brain Stimulation (nighttime aDBS)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Active, not recruiting Not applicable Interventional Results available

Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression

NCT05371041
View directory record Official record
Conditions
Tourette Syndrome
Interventions
Medtronic Percept Neurostimulator
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Cortical Electrophysiology of Response Inhibition in Parkinson's Disease

NCT06234995
View directory record Official record
Conditions
Parkinson Disease
Interventions
Levodopa, Clinical DBS Setting, Sham DBS, DBS Setting Maximizing Prefrontal Activation, DBS Setting Minimizing Prefrontal Activation
Drug · Device
Lead sponsor
Emory University
Other
Eligibility
45 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Not applicable Interventional

Cuneiform Nucleus (CnF) Deep Brain Stimulation for Gait Facilitation Following Spinal Cord Injury

NCT07109804
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Deep Brain Stimulation (DBS), Deep Brain Stimulation (DBS) Device Implant Procedure, Training Sessions
Device · Procedure · Other
Lead sponsor
University of Miami
Other
Eligibility
22 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.2

NCT07339072
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - NAcc 5 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc 5 Hz TI Sham, Temporal Interference (TI) Electrical Stimulation - NAcc 10 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc 10 Hz TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed Not applicable Interventional

Identification of Clinically Relevant Markers of Deep Brain Stimulation Electrode Impedance

NCT02794233
View directory record Official record
Conditions
Parkinson Disease
Interventions
Impedance measurements
Other
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Not applicable Interventional

Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

NCT04715984
View directory record Official record
Conditions
Parkinson Disease
Interventions
Neurophysiology recordings, Neural stimulation
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder

NCT04806516
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Summit RC+S System with ECoG Paddles, One Month Blinded Discontinuation Period:
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Phase 2 Interventional

Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS

NCT07442747
View directory record Official record
Conditions
Parkinson's Disease, Deep Brain Stimulation
Interventions
Exercise
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting Not applicable Interventional

Optimizing Adaptive DBS for Parkinson's Disease

NCT07798271
View directory record Official record
Conditions
PARKINSON DISEASE (Disorder)
Interventions
aDBS-Extended (Medtronic Percept™), aDBS-Standard (Medtronic Percept™), Continuous DBS (cDBS) - Active Control (Medtronic Percept™)
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed Not applicable Interventional Results available

Use of Two Deep Brain Stimulation (DBS) Electrodes to Treat Post-Traumatic Tremor

NCT00954421
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 25, 2014 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting No phase listed Observational

Intraoperative Microelectrode Recordings Using MAVEN Compared to Standard Recording Apparatuses

NCT07868614
View directory record Official record
Conditions
Essential Tremor, Parkinson's Disease, Dystonia
Interventions
Multifunctional Apparatus for Voltammetry, Electrophysiology, and Neuromodulation (MAVEN)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Enrolling by invitation Not applicable Interventional

Cholinergic Deep Brain Stimulation for Alzheimer's Disease

NCT05882344
View directory record Official record
Conditions
Alzheimer Disease, Early Onset, Dementia, Alzheimer Disease
Interventions
Device Implantation- Boston Scientific, VERCISE GENUS™ system, DBS Stimulation - Boston Scientific, VERCISE GENUS™ system
Procedure · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease

NCT05400499
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.1

NCT07215299
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - NAcc TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc TI Sham, Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed Not applicable Interventional

Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease

NCT04620551
View directory record Official record
Conditions
Parkinson Disease, Sleep Fragmentation
Interventions
Sub-clinical stimulation
Device
Lead sponsor
University of Nebraska
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 19, 2026, 9:50 PM EDT
Completed No phase listed Observational

Deep Brain Stimulation in Patients With LUTS

NCT03202251
View directory record Official record
Conditions
Bladder Dysfunction, Neurogenic Bladder
Interventions
It's is a cohort
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 19, 2026, 9:50 PM EDT