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ClinicalTrials.gov public records Last synced Oct 20, 2026, 3:17 AM EDT

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Showing 313–336 of 415 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: DBS Clear all
Completed Not applicable Interventional

A Responsive Closed-Loop Approach to Treat Freezing of Gait in Parkinson's Disease

NCT02318927
View directory record Official record
Conditions
Parkinsons Disease
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 20, 2026, 3:17 AM EDT
Completed No phase listed Observational Results available

Follow Up Study for Treatment of Parkinson's Disease With Deep Brain Stimulation

NCT01022073
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 95 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
12
States / cities
Los Angeles, California • San Francisco, California • West Los Angeles, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2016 · Synced Oct 20, 2026, 3:17 AM EDT
Recruiting Not applicable Interventional

Imaging Core Aim 2, and Udall Project 2 Aim 2

NCT06998303
View directory record Official record
Conditions
Parkinson Disease
Interventions
Bipolar DBS stimulation
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Not applicable Interventional Results available

Modulation of Emotion Perception in Humans Via Amygdala Stimulation

NCT05292183
View directory record Official record
Conditions
Refractory Epilepsy
Interventions
Electrical Stimulation
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Not applicable Interventional Results available

Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology

NCT03409120
View directory record Official record
Conditions
Dystonia-Parkinsonism, Adult-Onset, Parkinson Disease
Interventions
Boston Scientific Vercise PC IPG with directional DBS lead
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Oct 20, 2026, 3:17 AM EDT
Recruiting No phase listed Observational

Adaptive DBS to Offset STN Dysregulation During Exercise in PD

NCT06296810
View directory record Official record
Conditions
Parkinson Disease
Interventions
aDBS
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Not applicable Interventional Results available

Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait Using Neural and Kinematic Feedback

NCT04043403
View directory record Official record
Conditions
Parkinson Disease
Interventions
Open Loop DBS, Adaptive (Closed Loop) DBS, Intermittent Open Loop DBS
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Not applicable Interventional

Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy

NCT04897776
View directory record Official record
Conditions
Epilepsy, Temporal Lobe
Interventions
Central Thalamic Stimulation, Hippocampal Stimulation
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
New Haven, Connecticut • Rochester, Minnesota • Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Not applicable Interventional Results available

Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa

NCT04333498
View directory record Official record
Conditions
Therapeutic Adherence and Compliance
Interventions
Feedback on DBS Concentrations
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2023 · Synced Oct 20, 2026, 3:17 AM EDT
Completed No phase listed Observational

Evaluation of the Quality of Self-collected Blood Spot Specimens for Laboratory HIV Testing - An InvolveMENt Sub Study

NCT02043041
View directory record Official record
Conditions
HIV
Interventions
Number of DBS Spots
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2015 · Synced Oct 20, 2026, 3:17 AM EDT
Active, not recruiting Not applicable Interventional

Investigating Basal Ganglia-Cortical Physiology During Sleep and Its Modulation by Adaptive Deep Brain Stimulation in Parkinson Disease

NCT07808346
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
adaptive DBS (aDBS)
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 20, 2026, 3:17 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Early Parkinson's Disease (PD) Cross-Sectional

NCT00817453
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
35 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2011 · Synced Oct 20, 2026, 3:17 AM EDT
Not yet recruiting Early Phase 1 Interventional

Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation

NCT07721272
View directory record Official record
Conditions
Epilepsy, Essential Tremor, Seizures, Memory Consolidation, Memory Disorders, Memory Replay, Memory Encoding, Cognitive Control, Motor Abilities
Interventions
Cobenfy KarXT pill (50/20 mg), Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 20, 2026, 3:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Electrophysiological Recording for Patients Receiving Deep Brain Stimulation Electrode for Treatment-resistant Obsessive-compulsive Disorder

NCT01429558
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Subthalamic Deep Brain Stimulation (DBS) in Parkinson's Disease

NCT02012647
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Transcranial Magnetic Stimulation (TMS), Motor Physiology Testing
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Oct 20, 2026, 3:17 AM EDT
Terminated No phase listed Observational

Ataxia in Essential Tremor: Describing the Differences Between Disease Process and Treatment Effect

NCT03769961
View directory record Official record
Conditions
Essential Tremor, Deep Brain Stimulation, Ataxia, Cerebellar Diseases
Interventions
No intervention
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Oct 20, 2026, 3:17 AM EDT
Not listed Not applicable Interventional

Automated Deep Brain Stimulation Programming Using Functional Mapping

NCT02765282
View directory record Official record
Conditions
Parkinson Disease
Interventions
Algorithm based programming using Kinesia-based assessment
Device
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
35 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 20, 2026, 3:17 AM EDT
Enrolling by invitation Not applicable Interventional

Adaptive Deep Brain Stimulation for Freezing of Gait in Parkinson's Disease

NCT06819020
View directory record Official record
Conditions
Parkinson Disease
Interventions
Percept RC
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 20, 2026, 3:17 AM EDT
Active, not recruiting Not applicable Interventional

Remote Optimization, Adjustment and Measurement for Deep Brain Stimulation

NCT05269862
View directory record Official record
Conditions
Parkinson Disease
Interventions
Abbott Infinity DBS systems with the NeuroSphere Virtual Clinic feature, Abbott Infinity DBS systems with the NeuroSphere Virtual Clinic feature (virtual clinic and in-clinic sessions)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
11
States / cities
Tucson, Arizona • Sacramento, California • Miami, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 20, 2026, 3:17 AM EDT
Completed No phase listed Observational

DiSCERN: Advanced PD Therapy Candidacy and Evaluation System

NCT05351580
View directory record Official record
Conditions
Parkinson Disease
Interventions
DiSCERN
Device
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Not applicable Interventional

Deep Brain Stimulation in Patients With Parkinson's Disease

NCT00586079
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep brain stimulation surgery.
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 82 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 18, 2016 · Synced Oct 20, 2026, 3:17 AM EDT
Recruiting Early Phase 1 Interventional

REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study

NCT07228286
View directory record Official record
Conditions
Disorders of Consciousness
Interventions
Deep brain stimulation (DBS) electrode implantation
Device
Lead sponsor
Samuel Snider, MD
Other
Eligibility
18 Years to 55 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 20, 2026, 3:17 AM EDT
Completed No phase listed Observational Results available

DBS for Home Monitoring in Children With Kidney Transplantation

NCT01931397
View directory record Official record
Conditions
Kidney Disease
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
2 Years to 21 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 20, 2026, 3:17 AM EDT
Completed Not applicable Interventional

Deep Brain Stimulation for Treatment-Resistant Obsessive Compulsive Disorder

NCT00057603
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Deep Brain Stimulation
Procedure
Lead sponsor
University of Florida
Other
Eligibility
23 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 9, 2011 · Synced Oct 20, 2026, 3:17 AM EDT