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ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 415 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: DBS Clear all
Completed Not applicable Interventional Results available

Electrical Stimulation of the Dentate Nucleus for Upper Extremity Hemiparesis Due to Ischemic Stroke

NCT02835443
View directory record Official record
Conditions
Stroke
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Enspire DBS Therapy, Inc.
Industry
Eligibility
25 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 13, 2023 · Synced Oct 20, 2026, 4:01 AM EDT
Completed Not applicable Interventional Results available

Clinical Outcomes of Deep Brain Stimulator (DBS) Electrodes Placed Using Intraoperative Computed Tomography (CT) and Frameless Stereotaxis

NCT01703598
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulation, DBS surgery
Device · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 20, 2026, 4:01 AM EDT
Completed Not applicable Interventional Results available

Brain Stimulation for the Treatment of Tourette Syndrome

NCT01329198
View directory record Official record
Conditions
Tourette Syndrome
Interventions
NeuroPace RNS® System Deep Brain Stimulator
Device
Lead sponsor
University of Florida
Other
Eligibility
25 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 8, 2018 · Synced Oct 20, 2026, 4:01 AM EDT
Completed No phase listed Observational

Neurotransmitter Measurements Using (WINCS) During Deep Brain Stimulation Neurosurgery

NCT01705301
View directory record Official record
Conditions
Essential Tremor, Parkinson's Disease, Dystonia
Interventions
WINCS
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 3, 2017 · Synced Oct 20, 2026, 4:01 AM EDT
Completed Not applicable Interventional Results available

Low Frequency Electrical Stimulation of the Fornix in Intractable Mesial Temporal Lobe Epilepsy (MTLE)

NCT02383407
View directory record Official record
Conditions
Mesial Temporal Lobe Epilepsy
Interventions
Medtronic Deep Brain Stimulation
Device
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional

Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

NCT06848530
View directory record Official record
Conditions
Movement Disorders
Interventions
Prescribed Medications, Deep brain stimulation adjustment
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ventrointermediate Nucleus (VIM DBS) and Working Memory

NCT00906412
View directory record Official record
Conditions
Essential Tremor
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Oct 20, 2026, 4:01 AM EDT
Completed No phase listed Observational Results available

Intraoperative Investigation of a Directional Lead and Local Field Potentials for the Optimization of Stimulation Efficacy

NCT03630302
View directory record Official record
Conditions
Parkinson
Interventions
DBS
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 20, 2026, 4:01 AM EDT
Not listed Not applicable Interventional

LFP Correlates of Movement Disorders

NCT02115802
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Activa PC+S
Device
Lead sponsor
Colorado Neurological Institute
Other
Eligibility
21 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional

Aim 3 Particle Swarm Optimization PIGD

NCT05934747
View directory record Official record
Conditions
Parkinson's Disease and Parkinsonism
Interventions
DBS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting No phase listed Observational

A Multicenter Pediatric Deep Brain Stimulation Registry

NCT06585618
View directory record Official record
Conditions
Dystonia, Epilepsy in Children, Cerebral Palsy, Tourette Syndrome, Obsessive-Compulsive Disorder, Neurologic Disorder, Movement Disorders in Children, Movement Disorders, Deep Brain Stimulation
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety and Efficacy of CERE-120 in Subjects With Parkinson's Disease

NCT00985517
View directory record Official record
Conditions
Idiopathic Parkinson's Disease
Interventions
CERE-120: Adeno-Associated Virus Delivery of Neurturin, Sham Surgery
Biological · Procedure
Lead sponsor
Sangamo Therapeutics
Industry
Eligibility
35 Years to 70 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
11
States / cities
Birmingham, Alabama • Palo Alto, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional

Safety and Feasibility of DBS for Bipolar Depression

NCT07745374
View directory record Official record
Conditions
Bipolar I Disorder, Bipolar Depression
Interventions
Medtronic Percept PC DBS system
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
22 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Completed Phase 4 Interventional Results available

RECHARGE Sub-Study to the Implantable Systems Performance Registry (ISPR)

NCT00998660
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia
Interventions
Activa RC
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
7 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Cincinnati, Ohio • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2015 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional

Closed-Loop Deep Brain Stimulation for Major Depression

NCT04004169
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Stimulation-ON, Stimulation-OFF, Stimulation-ON Active Control
Device
Lead sponsor
Andrew Krystal
Other
Eligibility
22 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2035
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Deep Brain Stimulation Surgery for Focal Hand Dystonia

NCT02911103
View directory record Official record
Conditions
Dystonia, Focal Dystonia, Musician's Dystonia
Interventions
DBS surgery, Medtronic Activa Rechargeable System
Procedure · Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
22 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Active, not recruiting Not applicable Interventional

Responsive Deep Brain Stimulator for Essential Tremor

NCT02649166
View directory record Official record
Conditions
Essential Tremor
Interventions
Deep brain stimulation, Closed-loop deep brain stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting No phase listed Observational

Udall Project 2 Aim 2A&C

NCT05656586
View directory record Official record
Conditions
Parkinson Disease
Interventions
observational-- no intervention
Other
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

NCT06960096
View directory record Official record
Conditions
Deep Brain Stimulation, Parkinson Disease
Interventions
DBS combined with fMRI
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Completed Not applicable Interventional

Non-invasive Measurement of Brain Oxygen Levels in People With Subthalamic Deep Brain Stimulators

NCT02278406
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep brain stimulator
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Oct 20, 2026, 4:01 AM EDT
Withdrawn No phase listed Observational

ON/OFF Stimulation and Impulsivity in Patients With Deep Brain Stimulators

NCT01506206
View directory record Official record
Conditions
Obsessive Compulsive Disorder, Major Depressive Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional

Investigating Inhibitory Control Networks in Parkinson's Disease

NCT04735458
View directory record Official record
Conditions
Parkinson Disease
Interventions
Procedure/Surgery: Response Inhibition and Deep Brain Stimulation in Parkinson's disease
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application

NCT05506085
View directory record Official record
Conditions
Laryngeal Dystonia, Adductor Spastic Dysphonia of Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 20, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

NCT04144972
View directory record Official record
Conditions
Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia, Complex Regional Pain Syndromes, Post-Stroke Pain, Post Radiation Brain Injury, Post Radiation Plexopathy, Nerve Root Avulsion
Interventions
Medtronic Summit RC+S or Percept RC
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
22 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 20, 2026, 4:01 AM EDT