Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:19 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 415 matching trials from the live ClinicalTrials.gov search.
Conditions
Obesity
Interventions
Deep Brain Stimulation of the Lateral Hypothalamic Area
Device
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
Not listed
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Parkinson Disease
Interventions
Forced and voluntary exercise
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Parkinson's Disease
Interventions
GUIDE software, Version 0.1, Clinically defined stimulation parameters
Device
Lead sponsor
Intelect Medical, Inc.
Industry
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
4
States / cities
Gainesville, Florida • Manhasset, New York • Kirkland, Washington + 1 more
Conditions
Movement Disorders
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Birmingham, Alabama
Active, not recruiting Not applicable Interventional

DBS for TRD With the Medtronic Summit RC+S

NCT04106466
Conditions
Major Depressive Disorder, Treatment Resistant Depression
Interventions
Medtronic Summit RC+S DBS system
Device
Lead sponsor
Helen Mayberg, MD
Other
Eligibility
25 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
New York, New York
Conditions
Essential Tremor
Interventions
Deep Brain Stimulation surgery
Procedure
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Phoenix, Arizona
Enrolling by invitation Not applicable Interventional

Closed Loop DBS Implanted RC+S Study

NCT03815656
Conditions
Parkinson Disease
Interventions
STN alone, GPi alone, STN + GPi, Closed-loop stimulation
Device
Lead sponsor
Dennis Turner, M.D.
Other
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Parkinson's Disease
Interventions
Activa PC+S
Device
Lead sponsor
Vibhor Krishna
Other
Eligibility
22 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Episodic Memory
Interventions
Brain stimulation
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Spinocerebellar Ataxia (SCA), Spinocerebellar Ataxia Type 6
Interventions
Deep Brain Stimulation (DBS)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
San Francisco, California
Conditions
Parkinson Disease
Interventions
STN DBS 10Hz, STN DBS 130Hz, STN DBS off
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM

NCT06661343
Conditions
HIV Prevention
Interventions
C4 Program, C4 + 3MV Program
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
New York, New York • Dallas, Texas
Conditions
Parkinson Disease
Interventions
Neurostimulation, Carbidopa 25/Levodopa 100Mg Tab
Device · Drug
Lead sponsor
David Escobar
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Asleep Versus Awake Deep Brain Stimulation Surgery

NCT02424929
Conditions
Parkinson's Disease
Interventions
Sedation, Original Surgery
Procedure
Lead sponsor
Providence Medical Research Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Spokane, Washington
Completed Not applicable Interventional Results available

Prevention of Neurosurgical Wound Infections

NCT00915967
Conditions
Surgical Wound Infections
Interventions
Vancomycin, Placebo (Saline Solution)
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Enrolling by invitation Not applicable Interventional

Connectomic Guided DBS for Parkinson's Disease

NCT06618157
Conditions
Parkinson Disease, Tremor, Dyskinesias
Interventions
Cerebellothalamic optimized deep brain stimulation, Pallidothalamic optimized deep brain stimulation, No deep brain stimulation, Usual care deep brain stimulation
Device · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Parkinson's Disease, Mild Cognitive Impairment
Interventions
Combined STN+NBM DBS
Device
Lead sponsor
Helen M. Bronte-Stewart
Other
Eligibility
21 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California
Conditions
Dystonia
Interventions
Deep brain stimulation (DBS)
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
7 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Parkinson's Disease, Dystonia
Interventions
interventional MRI for implantation of DBS electrodes, DBS electrodes
Procedure · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2019
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Observational Results available

Clinical Evaluation of the Infinity Deep Brain Stimulation System

NCT02989610
Conditions
Parkinson Disease
Interventions
Omnidirectional stimulation, Directional stimulation
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
21
States / cities
Sacramento, California • Aurora, Colorado • Gainesville, Florida + 16 more
Conditions
Parkinsons Disease
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
74 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Deep Brain Stimulation, Parkinson Disease, Apraxia, Motor
Interventions
Deep brain stimulation effect on apraxia
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Parkinson's Disease, Essential Tremor, Dystonia, Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Aurora, Colorado