Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 19, 2026, 7:40 PM EDT

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Showing 169–192 of 415 matching trials from the live ClinicalTrials.gov search.
Conditions
Parkinson Disease
Interventions
Nighttime Deep Brain Stimulation with Varying Amplitude Settings
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Parkinson Disease
Interventions
Unilateral dual-target (STN/GPi) DBS
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Parkinson Disease
Interventions
Personalized DBS adjustments
Procedure
Lead sponsor
Darlene Floden
Other
Eligibility
40 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Results available

Dried Blood Spot Testing of CMV Detection in HCT Recipients

NCT03910478
Conditions
Cytomegalovirus Infection
Interventions
DBS Self-Collection Kit, Standard Control Strategy
Device · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
15 Years to 99 Years
Enrollment
622 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
4
States / cities
Minneapolis, Minnesota • New York, New York • Houston, Texas + 1 more
Conditions
Movement Disorders
Interventions
Response Inhibition and Deep Brain Stimulation in Parkinson's disease
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Addressing Heavy Alcohol Use Consumption With Kudzu

NCT03709043
Conditions
Alcohol Use Disorder, Sexually Transmitted Diseases
Interventions
Standardized kudzu, Placebo, Sexually transmitted infection testing:, Medical Management (MM) counseling for alcohol use:, Urinalysis for novel alcohol biochemical markers for recent alcohol use:, Dried Blood Spot (DBS) Testing for PEth:, Behavioral survey measurements:, Ecological Momentary Assessment procedure:
Drug · Other · Diagnostic Test + 1 more
Lead sponsor
Glenn-Milo Santos
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Francisco, California
Conditions
Obsessive-Compulsive Disorder
Interventions
Medtronic Percept Deep Brain Stimulation Therapy [Sham Control Stimulation], Medtronic Percept Deep Brain Stimulation Therapy [Therapeutic stimulation]
Device
Lead sponsor
Nader Pouratian
Other
Eligibility
22 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Alzheimer Disease
Interventions
DBS-f On, DBS Off
Device
Lead sponsor
Functional Neuromodulation Ltd
Industry
Eligibility
65 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
13
States / cities
Phoenix, Arizona • Los Angeles, California • Stanford, California + 10 more
Conditions
Essential Tremor, Deep Brain Stimulation
Interventions
Alternating stimulation, Placebo
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Essential Tremor
Interventions
Deep brain stimulation of the VIM Thalamic nuclei
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries
Interventions
Open-Loop DBS, Sham Stimulation, Closed-Loop DBS
Device
Lead sponsor
Prasad Shirvalkar, MD, PhD
Other
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
San Francisco, California
Conditions
Dystonia
Interventions
Activa PC Primary Cell Neurostimulator - (Model 37601), Activa RC Rechargeable Neurostimulator - (Model 37612), Activa SC Single Cell Neurostimulator (Models 37602/37603), DBS Lead - (Model 3387, DBS Extension - (Models 37085/6), Patient Programmer - (Model 37642), Test Stimulator - (Model 3625), N'Vision Clinician Programmer - (Model 8840), N'Vision Software Application Card - (Model 8870)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 25 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years to 75 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
22
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 18 more
Recruiting Not applicable Interventional

Motor Network Physiology

NCT04957095
Conditions
Parkinson Disease, Essential Tremor
Interventions
Apomorphine Injectable Solution, Subcortical Stimulation
Drug · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Essential Tremor
Interventions
VIM Stimulation, PSA Stimulation, VIM+PSA Stimulation
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Chronic Pain
Interventions
Deep Brain Stimulation for Thalamic Pain Syndrome
Device
Lead sponsor
Andre Machado
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Not yet recruiting Not applicable Interventional

VC/VS for Apathy in PD

NCT06991335
Conditions
Parkinson Disease, Deep Brain Stimulation, Apathy
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Nora Vanegas
Other
Eligibility
40 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Houston, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral and Neural Characteristics of Adaptive Speech Motor Control

NCT06164717
Conditions
Speech
Interventions
Auditory feedback perturbation during speech, Visual feedback perturbation during reaching, DBS stimulation ON/OFF
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
4 Years and older
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Terminated No phase listed Observational

Dried Blood Spot- Statin Pilot Study

NCT02402803
Conditions
Hyperlipidemias, Cardiovascular Diseases
Interventions
Dried blood spot testing and phlebotomy
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Parkinson Disease
Interventions
tDCS
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obesity
Interventions
DBS of the LHA
Device
Lead sponsor
donald whiting
Other
Eligibility
22 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Alzheimer Dementia (AD)
Interventions
Intermittent deep brain stimulation of the nucleus basalis of Meynert
Device
Lead sponsor
Augusta University
Other
Eligibility
65 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Obesity
Interventions
Deep Brain Stimulation Device
Device
Lead sponsor
Ali Rezai, MD
Other
Eligibility
22 Years to 60 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Columbus, Ohio