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ClinicalTrials.gov public records Last synced Sep 30, 2026, 5:43 AM EDT

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Showing 25–45 of 45 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: DBS of the STN Clear all
Completed Phase 3 Interventional

Deep Brain Stimulation for Parkinson's Disease Trial

NCT00053625
View directory record Official record
Conditions
Parkinson's Disease
Interventions
deep brain stimulation
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years to 75 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2009
U.S. locations
2
States / cities
Atlanta, Georgia • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 3, 2015 · Synced Sep 30, 2026, 5:43 AM EDT
Completed Not applicable Interventional

Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease

NCT04620551
View directory record Official record
Conditions
Parkinson Disease, Sleep Fragmentation
Interventions
Sub-clinical stimulation
Device
Lead sponsor
University of Nebraska
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 30, 2026, 5:43 AM EDT
Completed Not applicable Interventional Results available

Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology

NCT03409120
View directory record Official record
Conditions
Dystonia-Parkinsonism, Adult-Onset, Parkinson Disease
Interventions
Boston Scientific Vercise PC IPG with directional DBS lead
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Sep 30, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional

Use of CereGate Therapy for Freezing of Gait in PD

NCT05292794
View directory record Official record
Conditions
Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
Interventions
CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
Device
Lead sponsor
CereGate Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
7
States / cities
Redwood City, California • Aurora, Colorado • Miami, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 30, 2026, 5:43 AM EDT
Completed Phase 3 Interventional Results available

Phase I Deep Brain Stimulation (DBS) vs. Best Medical Therapy (BMT) Trial

NCT00056563
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Bilateral Deep Brain Stimulation, best medical therapy
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
22 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
14
States / cities
Los Angeles, California • San Francisco, California • West Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Sep 30, 2026, 5:43 AM EDT
Completed Not applicable Interventional Results available

Physical Therapy and Deep Brain Stimulation in Parkinson Disease

NCT03181282
View directory record Official record
Conditions
Parkinson Disease
Interventions
Physical Therapy
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
30 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Sep 30, 2026, 5:43 AM EDT
Active, not recruiting Not applicable Interventional

The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy

NCT03582891
View directory record Official record
Conditions
Parkinson Disease, Dystonia
Interventions
Summit RC+S for Motor, 8-week pilot trial of Closed-loop vs. Open-loop Stimulation, Summit RC+S for Sleep
Device · Diagnostic Test
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 30, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional

Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)

NCT05070013
View directory record Official record
Conditions
Parkinson's Disease, Sleep Fragmentation
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of Nebraska
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Omaha, Nebraska • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Sep 30, 2026, 5:43 AM EDT
Recruiting No phase listed Observational

Udall Project 1 Aim 4

NCT05568199
View directory record Official record
Conditions
Parkinsons Disease, Deep Brain Stimulation
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 30, 2026, 5:43 AM EDT
Enrolling by invitation Not applicable Interventional

Effects of Stimulation Patterns of Deep Brain Stimulation

NCT02553525
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor, Multiple Sclerosis, Dystonia
Interventions
Therapeutic Stimulation Patterns, Symptogenic Stimulation Patterns
Procedure
Lead sponsor
Duke University
Other
Eligibility
21 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
3
States / cities
Gainesville, Florida • Atlanta, Georgia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Sep 30, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional

Stimulus-Evoked Directional Field Potentials to Guide Subthalamic and Pallidal DBS for PD

NCT06169852
View directory record Official record
Conditions
Parkinson Disease
Interventions
Unilateral dual-target (STN/GPi) DBS
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 30, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional

Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait

NCT06994728
View directory record Official record
Conditions
Parkinson Disease, Gait Disorders, Neurologic, Visuospatial/Perceptual Abilities
Interventions
Left STN-DBS on, right STN-DBS off first, Right STN-DBS on, left STN-DBS off first
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 30, 2026, 5:43 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Cortical Electrophysiology of Response Inhibition in Parkinson's Disease

NCT06234995
View directory record Official record
Conditions
Parkinson Disease
Interventions
Levodopa, Clinical DBS Setting, Sham DBS, DBS Setting Maximizing Prefrontal Activation, DBS Setting Minimizing Prefrontal Activation
Drug · Device
Lead sponsor
Emory University
Other
Eligibility
45 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 30, 2026, 5:43 AM EDT
Completed No phase listed Observational

DBS Frequency on Swallowing Function in Parkinson's Disease

NCT01935011
View directory record Official record
Conditions
Parkinson's Disease
Interventions
PD, DBS
Other
Lead sponsor
University of Chicago
Other
Eligibility
45 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Sep 30, 2026, 5:43 AM EDT
Enrolling by invitation Not applicable Interventional

Deep Brain Stimulation (DBS) of the Pedunculopontine Nucleus (PPN)

NCT04605263
View directory record Official record
Conditions
Parkinson Disease
Interventions
STN-PPN DBS Surgery, Deep Brain Stimulation Surgery (DBS)
Device · Procedure
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Sep 30, 2026, 5:43 AM EDT
Completed No phase listed Observational

Deep Brain Stimulation of the Subthalamic Nucleus (STN) and Cognitive Control

NCT00917722
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Sep 30, 2026, 5:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia

NCT01671527
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Transcranial magnetic stimulation (TMS)
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2016 · Synced Sep 30, 2026, 5:43 AM EDT
Terminated No phase listed Observational

Dried Blood Spot- Statin Pilot Study

NCT02402803
View directory record Official record
Conditions
Hyperlipidemias, Cardiovascular Diseases
Interventions
Dried blood spot testing and phlebotomy
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Sep 30, 2026, 5:43 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)

NCT00993291
View directory record Official record
Conditions
Parkinson Disease
Interventions
Frequency change to 60 Hz, Frequency change to 130 Hz
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 27, 2012 · Synced Sep 30, 2026, 5:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of a High Intensity Exercise Training Program in Patients With Parkinson's Disease

NCT02593955
View directory record Official record
Conditions
Parkinson's Disease
Interventions
PD exercise, Sleep Hygiene
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
45 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Sep 30, 2026, 5:43 AM EDT
Active, not recruiting Phase 1 Interventional

Cont. of a Study to Evaluate Implanting Peripheral Nerve Grafts Into Subjects With Parkinson's Disease (PD) During DBS

NCT02369003
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Autologous Peripheral Nerve Graft
Procedure
Lead sponsor
Craig van Horne, MD, PhD
Other
Eligibility
40 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 30, 2026, 5:43 AM EDT