- Conditions
- Parkinson Disease
- Interventions
- Nighttime Deep Brain Stimulation with Varying Amplitude Settings
- Other
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
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Showing 1–24
of 59
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Tremor
- Interventions
- Electromagnetic tracking, Tremor kinetics after DBS, Tremor kinetics before and after DBS
- Device · Procedure
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Parkinson's Disease
- Interventions
- Medtronic Activa PC+S System with Chronic Neural Recording, Effort-Reward Decision-Making Task, Prefrontal Cortex Stimulation, Tablet-Based Mood Tracking (Immediate Mood Scaler)
- Device · Behavioral · Other
- Lead sponsor
- Simon J. Little, MBBS, PhD
- Other
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Parkinson Disease, REM Behavior Disorder
- Interventions
- Sleep, PD and DBS
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Parkinson Disease
- Interventions
- Rhythmic Auditory Stimulation (RAS)
- Behavioral
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Parkinson's Disease
- Interventions
- Isoflurane, Remifentanil, Propofol
- Drug
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2011
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Parkinson Disease
- Interventions
- Neural recordings and stimulation
- Device
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Treatment-Refractory Schizophrenia
- Interventions
- Abbott Laboratories Infinity™ implantable deep brain stimulation system
- Device
- Lead sponsor
- Bradley Lega
- Other
- Eligibility
- 22 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Alzheimer Disease
- Interventions
- DBS-f On, DBS Off
- Device
- Lead sponsor
- Functional Neuromodulation Ltd
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 74 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 13
- States / cities
- Phoenix, Arizona • Los Angeles, California • Stanford, California + 10 more
- Conditions
- Parkinson Disease, Essential Tremor, Multiple Sclerosis, Dystonia
- Interventions
- Therapeutic Stimulation Patterns, Symptogenic Stimulation Patterns
- Procedure
- Lead sponsor
- Duke University
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2027
- U.S. locations
- 3
- States / cities
- Gainesville, Florida • Atlanta, Georgia • Durham, North Carolina
- Conditions
- Opioid-Related Disorders
- Interventions
- Deep Brain Stimulation
- Device
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 22 Years to 50 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Morgantown, West Virginia
- Conditions
- Parkinson's Disease
- Interventions
- DBS stimulator setting alteration, virtual reality simulator
- Other
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2020
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Parkinson Disease
- Interventions
- Deep Brain Stimulation
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Great Neck, New York
- Conditions
- Bipolar II Disorder, Bipolar II Disorder, Most Recent Episode Major Depressive
- Interventions
- Device: Stimulation-ON, Device: Stimulation-OFF, Device: Stimulation -ON Active Control
- Device
- Lead sponsor
- Andrew Krystal
- Other
- Eligibility
- 22 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2035
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Parkinson Disease, Deep Brain Stimulation, Motivation
- Interventions
- Stimulation on, Stimulation off, Decision Making Task
- Other · Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2030
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Deep Brain Stimulation, Parkinson Disease
- Interventions
- DBS combined with fMRI
- Other
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Treatment Resistant Depression
- Interventions
- Medtronic SenSight Directional DBS lead
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2038
- U.S. locations
- 1
- States / cities
- Queens, New York
- Conditions
- Dystonia, Pediatric, Deep Brain Stimulation, Motor Development
- Interventions
- DBS
- Device
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Other
- Eligibility
- 6 Years to 21 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Parkinson Disease
- Interventions
- Deep Brain Stimulation (DBS)
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Parkinson's Disease
- Interventions
- PD, DBS
- Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Obsessive Compulsive Disorder, Major Depressive Disorder
- Interventions
- Not listed
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2024
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Charlestown, Massachusetts
- Conditions
- Obsessive-Compulsive Disorder, OCD
- Interventions
- Deep Brain Stimulation
- Device
- Lead sponsor
- Andrew Moses Lee, MD, PhD
- Other
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Parkinson's Disease
- Interventions
- Deep Brain Stimulator
- Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 45 Years to 70 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- High Intensity Focused Ultrasound, Deep Brain Stimulation
- Interventions
- Behavioral Assessment
- Behavioral
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia