- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Interventions
- Desvenlafaxine succinate sustained-release (DVS SR), Escitalopram
- Drug
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 40 Years to 70 Years · Female only
- Enrollment
- 595 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 52
- States / cities
- Peoria, Arizona • Pasadena, California • San Diego, California + 46 more
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- Conditions
- Depressive Disorder, Major
- Interventions
- Desvenlafaxine Succinate Sustained-Release (DVS SR), Placebo, Duloxetine 60 mg/day
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 638 participants
- Timeline
- 2006 – 2007
- U.S. locations
- 22
- States / cities
- Beverly Hills, California • Burbank, California • Encino, California + 19 more
- Conditions
- Major Depressive Disorder
- Interventions
- desvenlafaxine succinate sustained-release 50 mg/day, desvenlafaxine succinate sustained-release 100 mg/day, placebo
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 924 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 61
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • Arcadia, California + 50 more
- Conditions
- Major Depressive Disorder
- Interventions
- DVS-SR 50 mg, DVS-SR 100 mg, Placebo
- Drug
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 480 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 25
- States / cities
- Beverly Hills, California • Northridge, California • Farmington, Connecticut + 21 more
- Conditions
- Pharmacokinetics
- Interventions
- Tamoxifen, Tamoxifen and Desvenlafaxine Succinate Sustained Release
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 45 Years and older · Female only
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010
- U.S. locations
- 2
- States / cities
- Miami, Florida
- Conditions
- Vasomotor Symptoms
- Interventions
- desvenlafaxine succinate sustained release, Placebo
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 55
- States / cities
- Tucson, Arizona • Beverly Hills, California • Encinitas, California + 44 more
- Conditions
- Pharmacokinetics, Cytochrome P-450 CYP2D6, CYP3A4 Protein, Human
- Interventions
- Aripiprazole, Aripiprazole + desvenlafaxine succinate sustained release
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010
- U.S. locations
- 2
- States / cities
- Miami, Florida