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ClinicalTrials.gov public records Last synced Oct 23, 2026, 3:58 PM EDT

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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Daily avocado Clear all
Completed Phase 4 Interventional Results available

Clinical Trial to Evaluate Biafine Cream Versus Standard Care in Subjects With Actinic Keratosis Post Cryotherapy

NCT00695578
View directory record Official record
Conditions
Actinic Keratosis
Interventions
Biafine, Polysporin
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 31, 2018 · Synced Oct 23, 2026, 3:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Persea Americana for Total Health (PATH)-2

NCT05941728
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Avocado, Oil + Fiber, Average American Diet
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
25 Years to 74 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2023 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional

Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Obesity and HFpEF

NCT03966755
View directory record Official record
Conditions
Obesity, Heart Failure With Normal Ejection Fraction
Interventions
UFA dietary recommendations
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional

The Effect of Avocado on Cardiovascular Disease (CVD) Risk Factors

NCT01235832
View directory record Official record
Conditions
Cardiovascular Disease, Hyperlipidemia
Interventions
Avocado Diet, Lower-Fat Diet, Moderate Fat Diet
Other
Lead sponsor
Penn State University
Other
Eligibility
21 Years to 70 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Consumption of Potatoes, Avocados and Chickpeas and Cognitive Function in Older Adults

NCT01620567
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
avocado, potato or chickpea
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2019 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado

NCT04990817
View directory record Official record
Conditions
Elevated Triglycerides, Hypertriglyceridemia
Interventions
Average American Diet With SoFAS Replaced With Avocado, Average American Diet
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial

NCT03810378
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes
Interventions
Mediterranean Diet (Med-Plus), Well-Formulated Ketogenic Diet (WFKD)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 23, 2026, 3:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants

NCT06876935
View directory record Official record
Conditions
Gut Microbiome, Neurocognitive Correlates of Eating Habits, Infant Growth
Interventions
Daily avocado
Other
Lead sponsor
Arizona State University
Other
Eligibility
3 Months to 6 Months
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Oct 23, 2026, 3:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Persea Americana for Total Health (PATH ) Study

NCT02740439
View directory record Official record
Conditions
Obesity, Abdominal, Insulin Resistance, Insulin Sensitivity
Interventions
Avocado, Control
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
25 Years to 45 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Oct 23, 2026, 3:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

NCT06075914
View directory record Official record
Conditions
Sleep Deprivation, Nutritional Intervention
Interventions
Ketogenic Intervention, Mediterranean Intervention, Placebo, Ketone Ester
Other · Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 23, 2026, 3:58 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Dietary Oxalate and Immune Cell Function

NCT03877276
View directory record Official record
Conditions
Kidney Stone
Interventions
Breakfast, Spinach smoothie, Kale smoothie, Blended smoothie, V spinach smoothie, Sodium oxalate drink
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 23, 2026, 3:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties

NCT05688527
View directory record Official record
Conditions
Wrinkle
Interventions
Cleansing Balm, Toning Essence, Facial Serum, Moisturizer, Eye Cream
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
35 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 23, 2026, 3:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile

NCT07514663
View directory record Official record
Conditions
Hypercholesterolemia
Interventions
corn oil, Avocado Oil
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Habitual Diet and Avocado Trial

NCT03528031
View directory record Official record
Conditions
Intra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides High, Diet Habit, High Blood Sugar, Liver Fat, Dietary Modification, HDL Cholesterol, Low Serum, Cardiovascular Diseases, High Density Lipoprotein Deficiency, Low-density-lipoprotein-type, Cardiovascular Risk Factor, Diabetes
Interventions
Intervention Daily Avocado
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
25 Years and older
Enrollment
1,008 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
4
States / cities
Loma Linda, California • Los Angeles, California • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 23, 2026, 3:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults

NCT06137339
View directory record Official record
Conditions
Brain Aging
Interventions
Avocado Group
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
65 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 23, 2026, 3:58 PM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Avocado Consumption on Vascular Health

NCT01595607
View directory record Official record
Conditions
Focus: Avocado Consumption & Vascular Health
Interventions
Diet Treatment
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
28 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Oct 23, 2026, 3:58 PM EDT
Not listed Not applicable Interventional

Metabolomics Initiative: Mediterranean-amplified vs Habitual Western Diet on Food Signatures, Health, and Microbiome

NCT05500976
View directory record Official record
Conditions
Dietary Habits
Interventions
Semi-controlled dietary intervention - Western, Semi-controlled dietary intervention - MiniMed
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 69 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Exchanges With Avocado and Mango in Pre-diabetes

NCT05353790
View directory record Official record
Conditions
Pre Diabetes, Vascular Stiffness, Vascular Dilation, Cognitive Change, Retinal Vascular
Interventions
Meals + snacks: control, Meals + snacks: Avocado mango
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
25 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 23, 2026, 3:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.

NCT07566325
View directory record Official record
Conditions
Overweight (BMI > 25), Obesity (BMI>30), Hs-CRP
Interventions
Avocado, Control
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional

Unsaturated Fatty Acids Enriched-diet to Improve Cardiorespiratory Fitness, Metabolic Flexibility and Glucose Tolerance in Obese Patients

NCT03310099
View directory record Official record
Conditions
Heart Failure With Normal Ejection Fraction, Obesity
Interventions
Increasing daily unsaturated fatty acid consumption
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 23, 2026, 3:58 PM EDT
Not yet recruiting Not applicable Interventional

Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

NCT07417891
View directory record Official record
Conditions
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Shoulder, Osteoarthritis, Mild Cognitive Impairment, MCI, Mild Cognitive Impairment (MCI), Dementia
Interventions
Well-formulated ketogenic diet
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
55 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fairway, Kansas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 23, 2026, 3:58 PM EDT
Terminated Not applicable Interventional

Study of Dietary Composition in Crohn's Disease

NCT04431700
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Crohn Disease
Interventions
Anti-inflammatory diet, Regular diet
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 23, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

NCT03430310
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Low Glycemic Diet, Control Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
35 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 23, 2026, 3:58 PM EDT