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ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:49 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Decompression Clear all
Not listed Phase 3 Interventional

Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar Discectomy

NCT04574778
View directory record Official record
Conditions
Pain, Postoperative, Spine Surgery
Interventions
Acetaminophen
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Sep 2, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Comparative Study of Sham Versus Mild® Procedure in Patients Diagnosed With Symptomatic Lumbar Central Canal Stenosis

NCT01129921
View directory record Official record
Conditions
Lumbar Spine Stenosis Central Canal
Interventions
Percutaneous Lumbar Decompression, Sham lumbar decompression
Device
Lead sponsor
Napa Pain Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Napa, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2013 · Synced Sep 2, 2026, 5:49 PM EDT
Withdrawn No phase listed Observational

Real-Time Accurate Pathology Inspection and Decompression Study

NCT05347108
View directory record Official record
Conditions
Spine Injuries and Disorders, Pain, Chronic, Pain, Back, Pain, Neck, Radiculopathy
Interventions
laser-assisted neural decompression (LAND) procedure
Procedure
Lead sponsor
KM Clinical Research Group
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lā‘ie, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Sep 2, 2026, 5:49 PM EDT
Not listed Phase 2 Interventional

Surgical Management of Spinal Cord Injuries In Neck

NCT00475748
View directory record Official record
Conditions
Central Cord Syndrome, Spinal Cord Injury, Quadriparesis
Interventions
Early and late surgery for traumatic central cord syndrome
Procedure
Lead sponsor
Maryland Department of Health and Mental Hygiene
Government
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2009 · Synced Sep 2, 2026, 5:49 PM EDT
Completed No phase listed Observational

TIPS Plus Transvenous Obliteration for Gastric Varices

NCT04044248
View directory record Official record
Conditions
Cirrhosis, Liver, Hypertension, Portal, Esophageal and Gastric Varices, Bleeding Gastric, Encephalopathy
Interventions
TIPS-obliteration
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
8 participants
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 2, 2026, 5:49 PM EDT
Recruiting Phase 4 Interventional

Contrast-enhanced Ultrasound in the Treatment of Acute Spinal Cord Injury

NCT06654804
View directory record Official record
Conditions
Acute Spinal Cord Injury
Interventions
Perflutren lipid
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 2, 2026, 5:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Anti-inflammatory Actions of Osteopathic Manipulative Treatment

NCT04177264
View directory record Official record
Conditions
Inflammation
Interventions
Occipito-Atlantal Decompression (OA DC), Sham Occipito-Atlantal Decompression (Sham OA DC), Splenic Lymphatic Pump Technique (SpLPT), Sham Splenic Lymphatic Pump Technique (Sham SpLPT), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham taVNS)
Procedure · Device
Lead sponsor
Burrell College of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Las Cruces, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 2, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

One vs. Two Stents for Gallbladder Disease

NCT07222527
View directory record Official record
Conditions
Recurrent Cholecystitis, Cholecystitis, Symptomatic Gallbladder Disease, Biliary Colic
Interventions
ERCP with one stent placement, ERCP with two stent placement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 2, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Soft Tissue Therapy and Exercise on Hamstring Tightness

NCT03651141
View directory record Official record
Conditions
Hamstring Tightness, Myofascial Pain, Musculoskeletal Pain
Interventions
Neurodynamic Sliding, Myofascial Decompression, Diathermy
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 25 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 2, 2026, 5:49 PM EDT
Active, not recruiting Not applicable Interventional

Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD

NCT04229017
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Anterior Cervical Discectomy and Fusion, Posterior Cervical Stabilization System (PCSS)
Procedure · Device
Lead sponsor
Providence Medical Technology, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
17
States / cities
Phoenix, Arizona • Encinitas, California • Los Gatos, California + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 2, 2026, 5:49 PM EDT
Withdrawn Not applicable Interventional

Indirect vs. Direct Decompression for Treatment of Central Stenosis: RCT

NCT04708977
View directory record Official record
Conditions
Patients With Spinal Stenosis Indicated for LLIF
Interventions
One-level lateral lumbar interbody fusion with Indirect Decompression, One-level lateral lumbar interbody fusion with Direct Decompression
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Sep 2, 2026, 5:49 PM EDT
Not listed Not applicable Interventional

Osteopathic Manipulation in Breastfed Newborns

NCT03945474
View directory record Official record
Conditions
Osteopathic Medicine, Breast Feeding
Interventions
Sham, Osteopathic Manipulation, OMT
Other
Lead sponsor
Methodist Medical Center of Illinois
Other
Eligibility
20 Hours to 2 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Sep 2, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Trial Comparing Metal Versus Plastic Stents for Preoperative Biliary Decompression

NCT01675908
View directory record Official record
Conditions
Obstructive Jaundice, Pancreatic Cancer
Interventions
Stent Dysfunction, Complications
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Sep 2, 2026, 5:49 PM EDT
Completed No phase listed Observational

The Coflex®COMMUNITY Study: An Observational Study of Coflex® Interlaminar Technology

NCT02457468
View directory record Official record
Conditions
Spinal Stenosis
Interventions
coflex
Device
Lead sponsor
Predicted, Reported and Observed Outcomes Foundation
Other
Eligibility
Not listed
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
28
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 23 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2019 · Synced Sep 2, 2026, 5:49 PM EDT
Completed Not applicable Interventional

OP-1 Putty for Posterolateral Fusions

NCT00677950
View directory record Official record
Conditions
Degenerative Lumbar Spondylolisthesis
Interventions
Spinal fusion
Procedure
Lead sponsor
Olympus Biotech Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
21
States / cities
Santa Monica, California • Stanford, California • Denver, Colorado + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2011 · Synced Sep 2, 2026, 5:49 PM EDT
Not listed No phase listed Observational

Ischemic Optic Neuropathy Decompression Trial Followup (IONDT Followup)

NCT00000126
View directory record Official record
Conditions
Ischemic Optic Neuropathy
Interventions
Surgery
Procedure
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1994
U.S. locations
24
States / cities
Los Angeles, California • San Francisco, California • Gainesville, Florida + 20 more
Source: ClinicalTrials.gov public record
Updated May 25, 2006 · Synced Sep 2, 2026, 5:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biopsychosocial Impact on Caregivers in Patients Undergoing Joint and Spine Surgery

NCT03059602
View directory record Official record
Conditions
Pain, Postoperative
Interventions
No specific treatment based intervention-health measurement instrument
Other
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Sep 2, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Age, Sex and Isometric Exercise on Ventricular-Vascular Interactions During Cardiac Unloading

NCT06939153
View directory record Official record
Conditions
Orthostatic Intolerance
Interventions
LBNP, LBNP + Isometric handgrip exercise
Other
Lead sponsor
Tracy Baynard
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 2, 2026, 5:49 PM EDT
Terminated Phase 4 Interventional Results available

Condition of Approval Study

NCT00517751
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
X-STOP PEEK
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
50 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
23
States / cities
Birmingham, Alabama • Tucson, Arizona • Campbell, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2018 · Synced Sep 2, 2026, 5:49 PM EDT
Active, not recruiting No phase listed Observational

Collecting Bone Graft During Spinal Decompression and Posterolateral Lumbar Fusion to Better Define Bone Making Cells

NCT01409954
View directory record Official record
Conditions
Pseudarthrosis After Fusion or Arthrodesis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 2, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Partial Rotator Cuff Repair vs. Superior Capsular Reconstruction for Irreparable Rotator Cuff Tears

NCT04742452
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Superior Capusular Reconstruction, Partial Rotator Cuff Repair
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • Cleveland, Ohio • Willoughby, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 2, 2026, 5:49 PM EDT
Completed No phase listed Observational

Mechanomyography for Predictor of Prognosis in CuTS and PND Patients

NCT04322448
View directory record Official record
Conditions
Cubital Tunnel Syndrome, Peroneal Nerve Entrapment
Interventions
Mechanomyography (MMG)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Rochester, Minnesota • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 2, 2026, 5:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Placement of Nasogastric Tubes for Gastric Decompression in Patients With Bronchiolitis

NCT04480970
View directory record Official record
Conditions
Bronchiolitis
Interventions
Nasogastric tube placement
Device
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
1 Day to 23 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Sep 2, 2026, 5:49 PM EDT
Terminated Phase 3 Interventional

Right to Left Cardiac Shunt Detection

NCT01773252
View directory record Official record
Conditions
Right to Left Shunt, Patent Foramen Ovale, Atrial Septal Defect
Interventions
Flow Detection System
Device
Lead sponsor
Cardiox Corporation
Industry
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
8
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2015 · Synced Sep 2, 2026, 5:49 PM EDT