Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 5, 2026, 8:20 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 51 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Deep Brain Stimulator Clear all

Conditions: Obsessive Compulsive Disorder, Major Depressive Disorder
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2024
U.S. locations: 2
States / cities: Boston, Massachusetts • Charlestown, Massachusetts

Conditions: Deep Brain Stimulation, PARKINSON DISEASE (Disorder)
Interventions: Deep Brain Stimulation; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 25 Years to 75 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Healthy
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: Not listed
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Parkinson's Disease
Interventions: Deep Brain Stimulation; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years to 89 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Parkinson's Disease
Interventions: DBS stimulator setting alteration, virtual reality simulator; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Epilepsy
Interventions: RNS® System implantation, RNS® System responsive stimulation; Procedure · Device
Lead sponsor: NeuroPace; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 32
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 29 more

Conditions: Spinal Cord Stimulation, Deep Brain Stimulation, Drug Infusion (Implantable Pumps), Sacral Neuromodulation
Interventions: Various; Device
Lead sponsor: MedtronicNeuro; Industry
Eligibility: Not listed
Enrollment: 10,981 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2016
U.S. locations: 43
States / cities: Huntsville, Alabama • Scottsdale, Arizona • Aliso Viejo, California + 40 more

Conditions: Parkinson's Disease Patients Undergoing Deep Brain Stimulation (DBS) Surgery
Interventions: Measuring electrical signals from the brain; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Obesity
Interventions: DBS of the LHA; Device
Lead sponsor: donald whiting; Other
Eligibility: 22 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Movement Disorders
Interventions: Prescribed Medications, Deep brain stimulation adjustment; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obsessive Compulsive Disorder, Major Depressive Disorder, Epilepsy
Interventions: Deep Brain Stimulator; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Boston, Massachusetts • Charlestown, Massachusetts

Conditions: Post Traumatic Stress Disorder
Interventions: Week 0 Medtronic 3387 electrodes/Activa PC amygdala DBS, Week 12 Medtronic 3387 electrodes/Activa PC amygdala DBS; Device
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 25 Years to 65 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Traumatic Brain Injury
Interventions: A multi-contact depth electrode; Device
Lead sponsor: Samuel Cramer; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Speech
Interventions: Auditory feedback perturbation during speech, Visual feedback perturbation during reaching, DBS stimulation ON/OFF; Behavioral · Other
Lead sponsor: University of Washington; Other
Eligibility: 4 Years and older
Enrollment: 507 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Obsessive-Compulsive Disorder
Interventions: Active DBS, Sham DBS; Device
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2024
U.S. locations: 9
States / cities: Redwood City, California • Washington D.C., District of Columbia • Gainesville, Florida + 6 more

Conditions: Parkinson's Disease, Tremor, Dystonia
Interventions: Alteration of DBS stimulator settings; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Epilepsy Intractable
Interventions: Cedrus RB series response pad; Adtech Behnke-Fried micro-electrodes; Neuralynx or Blackrock electrophysiology system; Blackrock Cerestim or Natus Nicolet stimulator; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 3 Years to 25 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cervical Dystonia
Interventions: Transcranial magnetic stimulation (TMS); Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Tourette Syndrome
Interventions: NeuroPace RNS® System Deep Brain Stimulator; Device
Lead sponsor: University of Florida; Other
Eligibility: 25 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Parkinson Disease
Interventions: Implantable pulse generator (deep brain stimulator); Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 20 Years and older
Enrollment: 175 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Obsessive-Compulsive Disorder
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 21 Years to 64 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Parkinson's Disease
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Dystonia
Interventions: Activa PC Primary Cell Neurostimulator - (Model 37601), Activa RC Rechargeable Neurostimulator - (Model 37612), Activa SC Single Cell Neurostimulator (Models 37602/37603), DBS Lead - (Model 3387, DBS Extension - (Models 37085/6), Patient Programmer - (Model 37642), Test Stimulator - (Model 3625), N'Vision Clinician Programmer - (Model 8840), N'Vision Software Application Card - (Model 8870); Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 7 Years to 25 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression
Interventions: Deep Brain Stimulation System; Device
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2002
U.S. locations: 1
States / cities: Providence, Rhode Island

Search by objective public record fields.

ON/OFF Stimulation and Impulsivity in Patients With Deep Brain Stimulators

Cortical Network Modulation by Subthalamic Nucleus DBS

Stimulating Deep Brain Regions With a Magnetic Stimulator

Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

The Effect of Low Frequency STN DBS on Sleep and Vigilance in Parkinson's Disease (PD) Patients

RNS® System Pivotal Study

Implantable Systems Performance Registry

Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks

Deep Brain Stimulation Effects in Patients With Chronic Refractory Obesity

Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators

A Pilot Study of Deep Brain Stimulation of the Amygdala for Treatment-Refractory Combat Post-Traumatic Stress Disorder

Depth Electrode Cortical Reverberation Monitoring After Traumatic Brain Injury

Behavioral and Neural Characteristics of Adaptive Speech Motor Control

Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder

Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders

Pediatric Epilepsy

Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia

Brain Stimulation for the Treatment of Tourette Syndrome

Study of Subthalamic Brain Stimulation in Parkinson Disease (PD)

Patient-specific, Effective, and Rational Functional Connectivity Targeting for DBS in OCD

Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease

Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults

Electrical Stimulation of the Internal Capsule for Intractable Depression