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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Deep brain stimulator Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral and Neural Characteristics of Adaptive Speech Motor Control

NCT06164717
View directory record Official record
Conditions
Speech
Interventions
Auditory feedback perturbation during speech, Visual feedback perturbation during reaching, DBS stimulation ON/OFF
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
4 Years and older
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Phase 2 Interventional

Electrical Stimulation of the Internal Capsule for Intractable Depression

NCT01069952
View directory record Official record
Conditions
Depression
Interventions
Deep Brain Stimulation System
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 23, 2012 · Synced Sep 11, 2026, 4:50 PM EDT
Terminated Not applicable Interventional

Deep Brain Stimulation of the nbM to Treat Mild Cognitive Impairment in Parkinson's Disease

NCT02924194
View directory record Official record
Conditions
Parkinson's Disease, Mild Cognitive Impairment
Interventions
stimulation ON, stimulation OFF
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
50 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Sep 11, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

NCT07455760
View directory record Official record
Conditions
Parkinson's Disease (PD), Essential Tremor
Interventions
Phoneme sequence learning, Cessation and re-enabling of stimulation of the STN, Cessation and re-enabling of stimulation of the VIM thalamic nucleus, Multisyllabic sequence learning
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia

NCT01671527
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Transcranial magnetic stimulation (TMS)
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 12, 2016 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Brain Stimulation for the Treatment of Tourette Syndrome

NCT01329198
View directory record Official record
Conditions
Tourette Syndrome
Interventions
NeuroPace RNS® System Deep Brain Stimulator
Device
Lead sponsor
University of Florida
Other
Eligibility
25 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Sep 11, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Human Intracranial Electrophysiology

NCT05529264
View directory record Official record
Conditions
Epilepsy
Interventions
Memory Tasks, Attention/arousal tasks, Language tasks, Visuospatial tasks, Auditory Tasks, Brain Stimulation, Social Emotional Task, Recording of facial expressions, Judgement/Impulsivity Task
Other · Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2032
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders

NCT01169324
View directory record Official record
Conditions
Parkinson's Disease, Tremor, Dystonia
Interventions
Alteration of DBS stimulator settings
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 11, 2026, 4:50 PM EDT
Completed No phase listed Observational

Study of Subthalamic Brain Stimulation in Parkinson Disease (PD)

NCT01113684
View directory record Official record
Conditions
Parkinson Disease
Interventions
Implantable pulse generator (deep brain stimulator)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
20 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 10, 2018 · Synced Sep 11, 2026, 4:50 PM EDT
Active, not recruiting Not applicable Interventional

Responsive Deep Brain Stimulator for Essential Tremor

NCT02649166
View directory record Official record
Conditions
Essential Tremor
Interventions
Deep brain stimulation, Closed-loop deep brain stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Recruiting No phase listed Observational

Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease

NCT06857851
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Phase 2 Interventional Results available

RNS® System Feasibility Study

NCT00079781
View directory record Official record
Conditions
Epilepsy
Interventions
RNS® System implantation, RNS® System responsive stimulation
Procedure · Device
Lead sponsor
NeuroPace
Industry
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
12
States / cities
Phoenix, Arizona • New Haven, Connecticut • Jacksonville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults

NCT03078816
View directory record Official record
Conditions
Dystonia
Interventions
Activa PC Primary Cell Neurostimulator - (Model 37601), Activa RC Rechargeable Neurostimulator - (Model 37612), Activa SC Single Cell Neurostimulator (Models 37602/37603), DBS Lead - (Model 3387, DBS Extension - (Models 37085/6), Patient Programmer - (Model 37642), Test Stimulator - (Model 3625), N'Vision Clinician Programmer - (Model 8840), N'Vision Software Application Card - (Model 8870)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 25 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Phase 2 Interventional

Electrical Stimulation of the Internal Capsule for Intractable Obsessive-compulsive Disorder (OCD)

NCT01061983
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Medtronic Activa Deep Brain Stimulation
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 24, 2013 · Synced Sep 11, 2026, 4:50 PM EDT
Completed No phase listed Observational

Implantable Systems Performance Registry

NCT00959296
View directory record Official record
Conditions
Spinal Cord Stimulation, Deep Brain Stimulation, Drug Infusion (Implantable Pumps), Sacral Neuromodulation
Interventions
Various
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
Not listed
Enrollment
10,981 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
43
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Aliso Viejo, California + 40 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Phase 3 Interventional Results available

RNS® System Pivotal Study

NCT00264810
View directory record Official record
Conditions
Epilepsy
Interventions
RNS® System implantation, RNS® System responsive stimulation
Procedure · Device
Lead sponsor
NeuroPace
Industry
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
32
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2013 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Clinical Outcomes of Deep Brain Stimulator (DBS) Electrodes Placed Using Intraoperative Computed Tomography (CT) and Frameless Stereotaxis

NCT01703598
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulation, DBS surgery
Device · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Sep 11, 2026, 4:50 PM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease

NCT05400499
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Withdrawn No phase listed Observational

Patient-specific, Effective, and Rational Functional Connectivity Targeting for DBS in OCD

NCT03244852
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 11, 2026, 4:50 PM EDT
Terminated Not applicable Interventional Results available

Long Term Follow-up of Deep Brain Stimulation for Treatment-Resistant Depression

NCT03360942
View directory record Official record
Conditions
Treatment Resistant Depression, Depressive Disorder, Treatment-Resistant, Depression, Bipolar
Interventions
SCC DBS
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Sep 11, 2026, 4:50 PM EDT
Not listed Phase 4 Interventional Results available

Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder

NCT00640133
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Active DBS, Sham DBS
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2024
U.S. locations
9
States / cities
Redwood City, California • Washington D.C., District of Columbia • Gainesville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Sep 11, 2026, 4:50 PM EDT
Terminated Not applicable Interventional Results available

Deep Brain Stimulation Effects on Gait and Balance in Patients With Parkinson's Disease

NCT02022735
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulator
Device
Lead sponsor
University of Miami
Other
Eligibility
45 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Sep 11, 2026, 4:50 PM EDT
Active, not recruiting Not applicable Interventional

Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study

NCT03778060
View directory record Official record
Conditions
Essential Tremor
Interventions
Cala TWO stimulator
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional

Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

NCT06303869
View directory record Official record
Conditions
Stroke, Brain Disease, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases
Interventions
Deep Brain Stimulation (DBS) of the Motor Thalamus
Device
Lead sponsor
Jorge Gonzalez-Martinez
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 11, 2026, 4:50 PM EDT