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ClinicalTrials.gov public records Last synced Oct 27, 2026, 4:33 PM EDT

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Showing 1–24 of 104 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Defibrillation Clear all
Completed Not applicable Interventional Results available

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

NCT02731326
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
AliveCor, Behavioral Altering Messaging
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 27, 2026, 4:33 PM EDT
Active, not recruiting No phase listed Observational

Enlighten Study: The EV-ICD Post Approval Registry

NCT06048731
View directory record Official record
Conditions
Ventricular Arrhythmia, Tachycardia
Interventions
Defibrillation using EV-ICD
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2037
U.S. locations
57
States / cities
Huntington Park, California • Redwood City, California • San Diego, California + 45 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 27, 2026, 4:33 PM EDT
Terminated Not applicable Interventional

Arterial Stiffness and Atrial Fibrillation

NCT04160663
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Carotid Ultrasound
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 95 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Oct 27, 2026, 4:33 PM EDT
Completed No phase listed Observational

Surface ECG Signal Recording for the Implantable Subcutaneous String Defibrillator (ISSD) Detection Algorithm Performance Assessment

NCT03408951
View directory record Official record
Conditions
Tachyarrhythmia, Arrhythmias, Cardiac
Interventions
Recording
Other
Lead sponsor
NewPace Ltd
Industry
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Roslyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 27, 2026, 4:33 PM EDT
Not listed Phase 4 Interventional

Rapid Atrial Fibrillation Treatment Strategy

NCT04092621
View directory record Official record
Conditions
New Onset Atrial Fibrillation, Sepsis, Respiratory Failure
Interventions
Amiodarone in Parenteral Dosage Form, Amiodarone Pill, Direct Current Cardioversion (DCC), Rate-control therapy
Drug · Procedure
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 27, 2026, 4:33 PM EDT
Completed Not applicable Interventional

Does Eliminating Coffee Avoid Fibrillation?

NCT05121519
View directory record Official record
Conditions
Atrial Fibrillation, Coffee
Interventions
Consume coffee, Avoid coffee
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 27, 2026, 4:33 PM EDT
Terminated Phase 1Phase 2 Interventional

Effect of Intravenous Lidocaine, Used to Attenuate Pain With Propofol Injection, on Defibrillation Threshold Testing

NCT03117166
View directory record Official record
Conditions
Pain
Interventions
lidocaine, Placebo
Drug
Lead sponsor
Drexel University College of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 27, 2026, 4:33 PM EDT
Withdrawn Not applicable Interventional

The Effect of Atrial Fibrillation Hemodynamics on Regulation of Cerebral Blood Flow

NCT00745602
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
non-invasive testing
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 27, 2026, 4:33 PM EDT
Active, not recruiting Phase 2 Interventional

A Study of IV HBI-3000 for the Conversion Recent Onset Atrial Fibrillation (AF)

NCT04680026
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
HBI-3000, Placebo
Drug
Lead sponsor
HUYABIO International, LLC.
Industry
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Naples, Florida • Springfield, Illinois • Tupelo, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 27, 2026, 4:33 PM EDT
Terminated Phase 3 Interventional Results available

Ranolazine for the Prevention of Atrial Fibrillation After Electrical Cardioversion

NCT01349491
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Ranolazine, Matching placebo
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Oct 27, 2026, 4:33 PM EDT
Active, not recruiting Not applicable Interventional

Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

NCT06735534
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
FARAPULSE™ Pulsed Field Ablation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
33
States / cities
Mobile, Alabama • Jonesboro, Arkansas • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 27, 2026, 4:33 PM EDT
Completed Phase 4 Interventional Results available

POWER (Pulse Width Optimized Waveform Evaluation Trial)

NCT00311181
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronization Therapy (CRT-D)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Birmingham, Alabama • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 27, 2026, 4:33 PM EDT
Completed Not applicable Interventional

SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation

NCT00535106
View directory record Official record
Conditions
Ventricular Fibrillation, Cardiac Arrest
Interventions
Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
Device · Other
Lead sponsor
New York City Fire Department
Government
Eligibility
Not listed
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2009 · Synced Oct 27, 2026, 4:33 PM EDT
Not listed No phase listed Observational

Clinical Decision Support for Atrial Fibrillation and Flutter

NCT05009225
View directory record Official record
Conditions
Atrial Fibrillation and Flutter
Interventions
Comprehensive ED AF management tool
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
16
States / cities
Antioch, California • Fremont, California • Manteca, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Oct 27, 2026, 4:33 PM EDT
Completed No phase listed Observational Results available

LifeVest Trends Validation Protocol

NCT02149290
View directory record Official record
Conditions
Heart Failure
Interventions
Trends-equipped LifeVest 4000
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
13
States / cities
Orange, California • Boca Raton, Florida • Lawrenceville, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Oct 27, 2026, 4:33 PM EDT
Active, not recruiting No phase listed Observational

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

NCT04033510
View directory record Official record
Conditions
Atrial Fibrillation, Cognitive Symptom, Executive Dysfunction, Cognitive Change, Cognitive Impairment, Cognitive Impairment, Mild
Interventions
Standard of Care Interventions to convert patient from atrial fibrillation to normal rhythm
Other
Lead sponsor
David Brunk, PA-C, MMS
Other
Eligibility
35 Years to 80 Years
Enrollment
600 participants
Timeline
2019 – 2027
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 27, 2026, 4:33 PM EDT
Completed Not applicable Interventional

Acute Study to Collect Electrical Signals From the Heart Using a Special Lead

NCT02772380
View directory record Official record
Conditions
Tachycardia, Ventricular Arrhythmias
Interventions
Defibrillation following induction of VT/VF
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
14
States / cities
Scottsdale, Arizona • Hartford, Connecticut • Jacksonville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 27, 2026, 4:33 PM EDT
Completed Phase 3 Interventional

Home Use of Automatic External Defibrillators to Treat Sudden Cardiac Arrest

NCT00047411
View directory record Official record
Conditions
Cardiovascular Diseases, Myocardial Infarction, Heart Diseases, Death, Sudden, Cardiac
Interventions
Cardiopulmonary Resuscitation, Automatic External Defibrillation
Other · Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
7,001 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 10, 2008 · Synced Oct 27, 2026, 4:33 PM EDT
Not listed Phase 4 Interventional

Study of Defibrillation Testing In Patients Undergoing Initial ICD Implantation

NCT01905007
View directory record Official record
Conditions
Ventricular Arrhythmias
Interventions
Defibrillation testing
Device
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Camden, New Jersey • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 22, 2013 · Synced Oct 27, 2026, 4:33 PM EDT
Completed Phase 1Phase 2 Interventional

Intra-Cardiac Echocardiography Guided Cardioversion(ICE-CHIP) Study

NCT00281073
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Intra-Cardiac Echocardiography guided Cardioversion, Intracardiac Echo, ICE
Device
Lead sponsor
EP MedSystems
Industry
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
5
States / cities
Jacksonville, Florida • Chicago, Illinois • Urbana, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated May 11, 2011 · Synced Oct 27, 2026, 4:33 PM EDT
Completed Phase 2Phase 3 Interventional

Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure

NCT00180258
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Cardiac Resynchronization Therapy with & without defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2007 · Synced Oct 27, 2026, 4:33 PM EDT
Completed No phase listed Observational Results available

Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy Post Approval Registry

NCT01294449
View directory record Official record
Conditions
Heart Failure
Interventions
MADIT-CRT ICD, MADIT-CRT CRT-D
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Oct 27, 2026, 4:33 PM EDT
Completed No phase listed Observational

Myocardial Injury Following Elective Direct Current Cardioversion for Atrial Arrhythmias

NCT04151966
View directory record Official record
Conditions
Cardioversion
Interventions
Blood sample collection
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Oct 27, 2026, 4:33 PM EDT
Recruiting No phase listed Observational

ASSURE WCD Clinical Evaluation - Post Approval Study (ACE-PAS)

NCT05135403
View directory record Official record
Conditions
Sudden Cardiac Arrest
Interventions
Defibrillation
Device
Lead sponsor
Kestra Medical Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5,179 participants
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 27, 2026, 4:33 PM EDT