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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Dentures Clear all
Completed Phase 2 Interventional

Dentures and Dental Implants in Treating Patients Undergoing Surgery for Mouth Cancer

NCT00006341
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Implant
Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
35 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2003
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Sep 11, 2026, 1:43 AM EDT
Enrolling by invitation Not applicable Interventional

Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

NCT06406751
View directory record Official record
Conditions
Dental Prosthesis
Interventions
MI Paste
Device
Lead sponsor
University of Iowa
Other
Eligibility
65 Years to 105 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 11, 2026, 1:43 AM EDT
Withdrawn No phase listed Observational

A Descriptive, Prospective Clinical Study to Evaluate Full Dentures Fabricated by Additive Manufacturing

NCT03997604
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Full Dentures created by additive manufacturing
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Northglenn, Colorado • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 16, 2022 · Synced Sep 11, 2026, 1:43 AM EDT
Terminated Not applicable Interventional Results available

Wear Characteristics of Denture Teeth

NCT01188226
View directory record Official record
Conditions
Dentures
Interventions
Denture teeth
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2016 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Clinical Performance of 3-Unit FPDs

NCT00223431
View directory record Official record
Conditions
Partial Edentulism
Interventions
all-ceramic fixed partial denture
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2004
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2005 · Synced Sep 11, 2026, 1:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

NCT06890676
View directory record Official record
Conditions
Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections, Oral Infections, Periapical Infections, Pneumonia, Diabetes
Interventions
Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous, Periodontal Therapy, Periodontal Maintenance Procedure, Application of Caries Arresting Medicament, Oral Hygiene Assistance, Referral for Treatment of Acute Oral Infection
Other · Procedure
Lead sponsor
Missouri Department of Health and Senior Services
Other
Eligibility
60 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jefferson City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive

NCT03037307
View directory record Official record
Conditions
Denture Retention
Interventions
Test Product, Positive Contol, Negative Control
Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 11, 2026, 1:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive

NCT07496164
View directory record Official record
Conditions
Denture Retention
Interventions
Experimental Denture Adhesive 1, Experimental Denture Adhesive 2, Experimental Denture Adhesive 3, Poligrip Power Hold + Seal
Device
Lead sponsor
HALEON
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive

NCT05173974
View directory record Official record
Conditions
Denture Retention
Interventions
Super Poligrip Free, Experimental Denture Adhesive 1, Experimental Denture Adhesive 2
Device
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Sep 11, 2026, 1:43 AM EDT
Not yet recruiting Not applicable Interventional

Clinical Outcomes of 3D Printed and Milled Complete Dentures

NCT07586774
View directory record Official record
Conditions
Edentulous Mouth, Edentulous Jaw
Interventions
Lucitone Digital Print, Lucitone Digital Fit
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress

NCT02928380
View directory record Official record
Conditions
Denture Retention
Interventions
Experimental Denture Adhesive, Reference (Marketed) Denture Adhesive
Device
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 85 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 26, 2018 · Synced Sep 11, 2026, 1:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Full-arch Monolithic Zirconia ISFDP Follow up

NCT02931968
View directory record Official record
Conditions
Edentulous
Interventions
Monolithic zirconia prosthesis
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Sep 11, 2026, 1:43 AM EDT
Not yet recruiting Not applicable Interventional

Comparative Study of Denture Fabrication Techniques

NCT07525011
View directory record Official record
Conditions
Complete Edentulism
Interventions
Traditional Complete Denture Fabrication, Easdent Digital Complete Denture Fabrication
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Not applicable Interventional

Entry Into Comprehensive Methadone Treatment Via Interim Maintenance

NCT00712036
View directory record Official record
Conditions
Opiate Dependence
Interventions
Interim, Comprehensive, Restored
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 8, 2015 · Synced Sep 11, 2026, 1:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic

NCT02834832
View directory record Official record
Conditions
Denture Stomatitis, Wear of Denture Teeth
Interventions
PECVD coating
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Oral and Dermal Tolerability Clinical Study of an Experimental Denture Wipe

NCT03478644
View directory record Official record
Conditions
Denture Cleansers
Interventions
Experimental Denture Wipe, Tap Water
Device · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 80 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2018 · Synced Sep 11, 2026, 1:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Immediate Versus Delayed Loading of Maxillary Overdenture Implants

NCT06038487
View directory record Official record
Conditions
Implant Complication
Interventions
Immediate loading of maxillary implant overdenture, Delayed loading of maxillary implant overdenture
Procedure
Lead sponsor
Case Western Reserve University
Other
Eligibility
21 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 11, 2026, 1:43 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Conventionally vs. Digitally Fabricated Complete Dentures: Clinical Treatment Outcome Differences

NCT02521935
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Complete traditional dentures, Complete CADCAM dentures
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oral Hygiene Intervention Pilot Study

NCT02668809
View directory record Official record
Conditions
Dental Caries, Gingivitis
Interventions
oral health assessment, Questionnaires, Clinical Exam, Microbiological sampling, Monitoring Adherence, Varnish application, Consent, Educational Program
Other
Lead sponsor
Leonardo Marchini
Other
Eligibility
21 Years to 120 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Sep 11, 2026, 1:43 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Removable Partial Denture Abutments Restored With Monolithic Zirconia Crowns

NCT03283709
View directory record Official record
Conditions
Crowns, Denture
Interventions
Full-contour monolithic zirconia abutment crowns, Conventional abutment crowns
Device
Lead sponsor
Hiroko Nagaoka
Other
Eligibility
25 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Sep 11, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting

NCT07273149
View directory record Official record
Conditions
Denture Retention
Interventions
Poligrip Power Max Hold + Seal
Device
Lead sponsor
HALEON
Industry
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 11, 2026, 1:43 AM EDT
Not yet recruiting Not applicable Interventional

Prevention of Oral Mucositis in Adults in With Hematologic Malignancy

NCT07809984
View directory record Official record
Conditions
Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Oral Mucositis
Interventions
Aloe Vera Mouthwash, Standard of Care
Dietary Supplement · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Oak Lawn, Illinois • Park Ridge, Illinois • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 11, 2026, 1:43 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive

NCT04473521
View directory record Official record
Conditions
Denture Retention
Interventions
Investigational denture adhesive cream, Super Poligrip Free
Device
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Sep 11, 2026, 1:43 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

An Observational Clinical Case Series Study to Assess Fit and Quality of Full Dentures Fabricated by AM

NCT04023006
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Removable prostheses
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Sep 11, 2026, 1:43 AM EDT