- Conditions
- Polypharmacy, Alzheimer's Disease and Related Dementias, Mild Cognitive Impairment
- Interventions
- Pharmacist-led deprescribing intervention
- Behavioral
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 474 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Benzodiazepine Dependence, Anxiety Disorders, Sleep Disturbance
- Interventions
- ALDER
- Behavioral
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Anxiety, Insomnia, Benzodiazepine, Deprescription
- Interventions
- Acupuncture, Yoga, Deprescribing
- Other
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Alzheimer's Disease, Dementia
- Interventions
- Placebo, Medication Therapy Management (MTM), Scopolamine patch
- Other · Drug
- Lead sponsor
- Daniela Moga
- Other
- Eligibility
- 65 Years to 101 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Benzodiazepine Use, Insomnia, Anxiety
- Interventions
- Benzodiazepine Medication Taper with Cognitive Behavioral Therapy
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease
- Interventions
- Beta blockers
- Drug
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Polypharmacy, Dementia, Multiple Chronic Conditions, Deprescribing, Mild Cognitive Impairment
- Interventions
- Educational Materials
- Other
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Reading, Pennsylvania
- Conditions
- Dementia
- Interventions
- PRIDE
- Other
- Lead sponsor
- National Institute on Aging (NIA)
- NIH
- Eligibility
- 18 Years to 120 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Lake Forest, Illinois • Palos Heights, Illinois
- Conditions
- Geriatric Assessment, Frail Elderly, Skilled Nursing Facilities, Patient-centered Care
- Interventions
- Deprescribing intervention
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 50 Years and older
- Enrollment
- 260 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Dementia, Alzheimer Disease, Late Onset
- Interventions
- Deprescribing of target anticholinergics, Usual Care
- Other
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 344 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 2
- States / cities
- Indianapolis, Indiana
- Conditions
- Hospices, Poly Pharmacy, Deprescriptions, Caregivers, Palliative Care, Prescription Drug Overuse, Interdisciplinary Communication
- Interventions
- NIA Medication Management - Active Comparator, STOPPFrail (Screening Tool of Older Persons Prescriptions), "Discontinuing Medication Appropriately" and "Understanding the Art of Communication about Deprescribing", "Key Approaches to Support Informal Family Caregivers in Managing Medications"
- Behavioral
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 65 Years to 110 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Danvers, Massachusetts
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
- Interventions
- Tamsulosin, Placebo
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 55 Years to 80 Years · Male only
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Hypothyroidism
- Interventions
- D-THIO (Deprescribing Thyroid Hormone In Older Adults), Enhanced usual care
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 900 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 3
- States / cities
- San Francisco, California • Ann Arbor, Michigan • Detroit, Michigan
- Conditions
- Prescribing Patterns, Physician, Physician's Practice Patterns, Drug Utilization Review
- Interventions
- Algorithmic Defaulting (Indication-Based Default), Active Physician Choice
- Behavioral
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 372 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Cancer
- Interventions
- Pharmacist-led deprescribing, Patient education
- Other
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Polypharmacy, Dementia, Quality of Life
- Interventions
- Shed-MEDS deprescribing intervention
- Behavioral
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 2
- States / cities
- Nashville, Tennessee
- Conditions
- Accidental Falls/Prevention and Control
- Interventions
- Injury Liaison Service
- Other
- Lead sponsor
- Hebrew SeniorLife
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Durham, North Carolina
- Conditions
- Alzheimer Disease
- Interventions
- Educational Materials
- Other
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 11,375 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Dementia
- Interventions
- PPC, Usual care
- Behavioral
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Diabetes, Dementia, Hypoglycemia; Drug
- Interventions
- STRIDE
- Behavioral
- Lead sponsor
- Joslin Diabetes Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Medication Adverse Effects, Older Adults (65 Years and Older), Polypharmacy, Polypharmacy Patients, Deprescribing
- Interventions
- Patient-tailored deprescribing assessment and intervention
- Behavioral
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Fall Risk
- Interventions
- Strengthening (Physical Therapy, Gerofit), Medication Reconciliation (Clinical Pharmacology), Home Safety Modification (Occupational Therapy)
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 65 Years and older
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Dementia
- Interventions
- STOP Falls D Educational Intervention
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 123 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Insomnia
- Interventions
- Cognitive Behavioral Therapy for Insomnia, Deprescribing
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania