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ClinicalTrials.gov public records Last synced Oct 23, 2026, 3:55 AM EDT

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Showing 529–552 of 4,835 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Depression Clear all
Recruiting Not applicable Interventional

Teenthrive 2: Treatments for Improving Mood in Teens

NCT07475845
View directory record Official record
Conditions
Depression in Adolescence
Interventions
Yoga-Based Intervention, group CBT
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Chatbot for Depression, Anxiety, and Eating Disorders

NCT06013137
View directory record Official record
Conditions
Depression, Anxiety, Eating Disorders
Interventions
Therabot
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 23, 2026, 3:55 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

The Impact of Ketamine on the Reward Circuitry of Suicidal Patients

NCT02532153
View directory record Official record
Conditions
Suicidal Ideation, Suicide
Interventions
Ketamine Hydrochloride
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2017 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Individualized Assessment and Treatment for Alcoholism II

NCT03233802
View directory record Official record
Conditions
Alcoholism
Interventions
Individualized Assess & Treatment (IATP), Packaged Cognitive-Behavioral (PCBT), Case Management (CaseM)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Physical and Psychosocial Well-being of African American Older Adults

NCT03716037
View directory record Official record
Conditions
Physical Activity, Psychosocial Stressors
Interventions
Physical Activity for Life (PAL)
Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
65 Years to 100 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Uniontown, Alabama
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Affect Treatment for Depression and Anxiety

NCT05203861
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Positive Affect Treatment, Negative Affect Treatment
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 23, 2026, 3:55 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Palliative Care Needs of Children With Rare Diseases and Their Families

NCT06938542
View directory record Official record
Conditions
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome, Early Infantile Epileptic Encephalopathy, FOXG1 Syndrome, KBG Syndrome, Noonan Syndrome, Severe Hemophilia A, Short Bowel Syndrome, Beta-Propeller Protein-Associated Neurodegeneration, Brain Injury of Prematurity With Periventricular Leukomalacia, Chromosome 17p13.3 Microdeletion Syndrome, Chromosome 1q43-1q44 Deletion, Cockayne Syndrome, Congenital Diaphragmatic Hernia, End-Stage Renal Disease With Cloacal Anomaly, Mitochondrial Depletion Disorder, Severe Factor VII Deficiency
Interventions
Family Centered pediatric palliative care for family caregivers of children with rare diseases.
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
12 Months to 99 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Phase 2 Interventional

Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD)

NCT05203341
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Placebo, NBI-1065845
Drug
Lead sponsor
Neurocrine Biosciences
Industry
Eligibility
18 Years to 65 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
17
States / cities
Birmingham, Alabama • Huntsville, Alabama • Riverside, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Implementation of Evidence-based Treatments for On-campus Eating Disorders

NCT02079142
View directory record Official record
Conditions
Eating Disorders (Excluding Anorexia Nervosa), Depression
Interventions
High Intensity Strategy: Train-the-trainer, Low Intensity Strategy: Expert Consultation
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Study of a Self-Help Depression Skills Program for College-Aged Youth

NCT00145054
View directory record Official record
Conditions
Depression
Interventions
MoodHelper Internet program for Depression Self-Help
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
14 Years to 24 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 24, 2006 · Synced Oct 23, 2026, 3:55 AM EDT
Enrolling by invitation Phase 2 Interventional

Ketamine Effects on Learning In Eating Disorders

NCT06736769
View directory record Official record
Conditions
Anorexia Nervosa, Atypical Anorexia Nervosa
Interventions
Ketamine infusion
Drug
Lead sponsor
Amanda Downey, MD
Other
Eligibility
16 Years to 26 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 23, 2026, 3:55 AM EDT
Recruiting Not applicable Interventional

Collaborative Care Model for Perinatal Wellness Support Services - Population-Level Equity-Centered Systems Change

NCT06849869
View directory record Official record
Conditions
Perinatal Mental Health
Interventions
COMPASS+
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
14,820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Taking Time to Connect: A Study of Programs for Hispanic Mothers Diagnosed With Cancer and Their Children

NCT03951454
View directory record Official record
Conditions
Cancer Survivorship
Interventions
Conexiones, Taking Time
Behavioral
Lead sponsor
New Mexico State University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
5
States / cities
Las Cruces, New Mexico • El Paso, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 23, 2026, 3:55 AM EDT
Active, not recruiting Phase 3 Interventional

Does Immediate Lymphatic Reconstruction Decrease the Risk of Lymphedema After Axillary Lymph Node Dissection

NCT04241341
View directory record Official record
Conditions
Breast Cancer Lymphedema
Interventions
Axillary Lymph Node Dissection with Immediate Lymphatic Reconstruction, Axillary Lymph Node Dissection without Immediate Lymphatic Reconstruction, quality-of-life questionnaires, measured by arm volume
Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Functional Connectivity in Mood Regulating Circuit In Bipolar Depression and Mania

NCT00457054
View directory record Official record
Conditions
Bipolar Depression
Interventions
Lithium
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 28, 2011 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Phase 4 Interventional

Safety and Efficacy of Vilazodone in Major Depressive Disorder

NCT01573598
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Placebo, Vilazodone
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 70 Years
Enrollment
1,219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
38
States / cities
Beverly Hills, California • Chino, California • Costa Mesa, California + 32 more
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Phase 3 Interventional

Study Comparing Adjunctive Risperidone Versus Placebo in Major Depressive Disorder That Is Not Responding to Standard Therapy

NCT00095134
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
risperidone
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years to 65 Years
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
70
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Sun City, Arizona + 60 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2011 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Family-based Crisis Intervention With Suicidal Adolescents in the ED

NCT02610309
View directory record Official record
Conditions
Suicide
Interventions
Family-Based Crisis Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2015 · Synced Oct 23, 2026, 3:55 AM EDT
Not listed Not applicable Interventional

Adapting the Tumor Board Model for Mental Illness and Cancer

NCT05837598
View directory record Official record
Conditions
Cancer, Severe Major Depression, Schizophrenia, Bipolar Disorder, Lung Cancer, Breast Cancer, Head and Neck Cancer, Gastrointestinal Cancer, Genitourinary Cancer
Interventions
Virtual Cancer and Mental Health Tumor Board
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Danvers, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact on Opioid Use of Bundling Medication-assisted Treatment With mHealth

NCT02712034
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
MAT + A-CHESS, MAT
Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Phase 2 Interventional Results available

A Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder

NCT00840034
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
LY2216684, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
24
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Carson, California + 21 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Oct 23, 2026, 3:55 AM EDT
Terminated Not applicable Interventional Results available

Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as Adjuvant Treatment for Depression

NCT01115699
View directory record Official record
Conditions
Depression
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 13, 2013 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Project MOVE Bipolar

NCT07767032
View directory record Official record
Conditions
Bipolar Disorder (BD)
Interventions
BA, SHE, HE, CBEX
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 23, 2026, 3:55 AM EDT
Completed Not applicable Interventional Results available

Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans

NCT00805532
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Behavioral Activation treatment, Treatment as Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 5, 2018 · Synced Oct 23, 2026, 3:55 AM EDT