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ClinicalTrials.gov public records Last synced Oct 28, 2026, 8:25 PM EDT

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Showing 1057–1080 of 4,843 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Depression Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors

NCT03304587
View directory record Official record
Conditions
Breast Cancer
Interventions
Polysomnography (PSG), Rectal thermistor 400 Series, Bright blue-green light, Dim red light, Digital foot candle datalogging light meter, Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue, Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance, Patient-Reported Outcomes Measurement Information System (PROMIS)-Depression, Patient-Reported Outcomes Measurement Information System (PROMIS)-Physical Function, Pittsburgh Sleep Quality Index (PSQI), Center for Epidemiological Studies - Depression, Montreal Cognitive Assessment (MoCA), European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ-C30), Daily Log
Diagnostic Test · Other
Lead sponsor
Michigan State University
Other
Eligibility
21 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional Results available

Acceptance-based Group Intervention for Binge Eating

NCT01757847
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2016 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional

3D Team Care for Cognitively Vulnerable Older Adults

NCT02945085
View directory record Official record
Conditions
Dementia, Depression, Delirium
Interventions
Home Based Care Team, Telephone Based Care Team
Other
Lead sponsor
UConn Health
Other
Eligibility
65 Years and older
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 28, 2026, 8:25 PM EDT
Recruiting Not applicable Interventional

Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury

NCT05497115
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Trauma Resilience and Recovery Program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Washington, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional

Biobehavioral Intervention to Enhance Hematopoietic Stem Cell Transplant Recovery

NCT02955043
View directory record Official record
Conditions
Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Plasma Cell Myeloma, Lymphoid Leukemia, Myeloid Leukemia, Myelodysplastic Syndromes, Multiple Myeloma
Interventions
Behavioral techniques
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 74 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effectiveness of Supplemental Calcium in Preventing Postpartum Depression

NCT00228033
View directory record Official record
Conditions
Depression, Depression, Postpartum
Interventions
Elemental calcium (as carbonate)
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 20, 2014 · Synced Oct 28, 2026, 8:25 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression

NCT01732055
View directory record Official record
Conditions
Partner Assisted Interpersonal Psychotherapy, Treatment as Usual
Interventions
Partner-Assisted Interpersonal Psychotherapy, Treatment as Usual
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Oct 28, 2026, 8:25 PM EDT
Terminated Not applicable Interventional

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care in Texas

NCT05270785
View directory record Official record
Conditions
Suicidal Ideation
Interventions
STAT-PC, YST-III
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 24 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 20, 2023 · Synced Oct 28, 2026, 8:25 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Glutamate Probes in Adolescent Depression

NCT02307617
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Disorder, Recurrent, Major Depressive Disorder, Remitted
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar Depression

NCT01390389
View directory record Official record
Conditions
Bipolar Depression
Interventions
Coenzyme Q10
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
55 Years to 89 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional Results available

Implementing Evidence in the Detection and Treatment of Post Stroke Depression

NCT00296140
View directory record Official record
Conditions
Mental Health, Neurology, Health Services
Interventions
self management of PSD symptoms, screening and treatment of PSD
Behavioral · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Gainesville, Florida • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Oct 28, 2026, 8:25 PM EDT
Not listed Not applicable Interventional

Body Image and Self-Care in HIV-Infected MSM

NCT01817621
View directory record Official record
Conditions
Body Image Disturbance, Medication Adherence
Interventions
Experimental Intervention, TAU
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engaging Seronegative Youth to Optimize HIV Prevention Continuum

NCT03134833
View directory record Official record
Conditions
HIV, Mental Health, Substance Use, STI
Interventions
Automated Messaging & Monitoring, Peer Support, Coaching
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
1,478 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional Results available

Connection to Care: Pilot Study of a Mobile Health Tool for Patients With Depression and Anxiety

NCT02497755
View directory record Official record
Conditions
Anxiety, Depression
Interventions
App for smartphone, smartphone
Behavioral · Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression

NCT02978326
View directory record Official record
Conditions
Postpartum Depression
Interventions
SAGE-217 15/20 mg Oral Solution, Placebo, SAGE 217 30 mg Capsules
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
27
States / cities
Little Rock, Arkansas • Beverly Hills, California • Oceanside, California + 24 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 28, 2026, 8:25 PM EDT
Recruiting Not applicable Interventional

Understanding the Neural Underpinnings of Risk-Taking Behavior in Psychiatric Disease

NCT07896343
View directory record Official record
Conditions
Depression - Major Depressive Disorder
Interventions
Approach-Avoidance Decision-Making Task
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Great Plains Internet Wellness Study for Aging

NCT04461184
View directory record Official record
Conditions
Internet Based Wellness Program, Obesity, Adult Population
Interventions
Internet Wellness Intervention for Aging
Behavioral
Lead sponsor
North Dakota State University
Other
Eligibility
65 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional

Psychotherapy Feasibility Pilot of the Carolina Recovery From Depression Protocol

NCT06590038
View directory record Official record
Conditions
Depression, Unipolar
Interventions
Single Session Psychotherapy Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy

NCT01453114
View directory record Official record
Conditions
Depression, Postpartum Depression, Antenatal Depression
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 28, 2026, 8:25 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Characterization and Treatment of Adolescent Depression

NCT03388606
View directory record Official record
Conditions
Depression
Interventions
Growth Mindset
Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
11 Years to 25 Years
Enrollment
4,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
3
States / cities
Los Angeles, California • Denver, Colorado • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Early Phase 1 Interventional

fMRI Study of tES in Major Depression

NCT04031547
View directory record Official record
Conditions
Depression
Interventions
Transcranial Electrical Stimulation (tES)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Phase 2 Interventional Results available

Buprenorphine for Late-Life Treatment Resistant Depression

NCT01071538
View directory record Official record
Conditions
Depression
Interventions
Buprenorphine
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Not applicable Interventional

Preventing Post-Stroke Depression

NCT00071643
View directory record Official record
Conditions
Depression, Cerebrovascular Accident
Interventions
Problem Solving Therapy, Escitalopram, Placebo
Behavioral · Drug · Other
Lead sponsor
Robert G. Robinson
Other
Eligibility
31 Years to 89 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
3
States / cities
Chicago, Illinois • Iowa City, Iowa • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 28, 2026, 8:25 PM EDT
Completed Phase 3 Interventional

Omega-3 Fatty Acids for Treatment of Depression in Adolescents

NCT00658476
View directory record Official record
Conditions
Depression
Interventions
Fish Oil, Cognitive Behavior Therapy, Placebo
Dietary Supplement · Behavioral · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2012 · Synced Oct 28, 2026, 8:25 PM EDT