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Showing 1–24 of 174 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Depression Cognitive Training Clear all
Completed Phase 1Phase 2 Interventional Results available

Ketamine + Mindfulness for Depression

NCT05168735
View directory record Official record
Conditions
Depression, Unipolar
Interventions
Intravenous Ketamine, Brief Mindfulness Exercises, Academic Exercises
Drug · Behavioral
Lead sponsor
Rebecca Price
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Sep 7, 2026, 5:05 AM EDT
Terminated Phase 1 Interventional

Cognitive Behavioral Therapy to Help HIV Infected Adults With Depression to Adhere to Antiretroviral Therapy

NCT00509340
View directory record Official record
Conditions
Depression, HIV Infection
Interventions
Cognitive behavioral therapy (CBT)
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Sep 7, 2026, 5:05 AM EDT
Withdrawn Phase 1 Interventional

Enhancing Processing Speed and Executive Functioning in Depressed Older Adults With Computerized Cognitive Training

NCT04836533
View directory record Official record
Conditions
Depression in Old Age, Depression
Interventions
Experimental: Computerized Cognitive Training, Experimental: Open-label antidepressant treatment, Active Comparator: Solitaire Training, Placebo Comparator: Placebo-controlled antidepressant treatment
Other · Drug
Lead sponsor
Queens College, The City University of New York
Other
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Phase 1 Interventional

PAPR: PAP + MBSR for Front-line Healthcare Provider COVID-19 Related Burnout

NCT05557643
View directory record Official record
Conditions
Depression, Burnout, Professional
Interventions
Psilocybin, Mindfulness-Based Stress Reduction (MBSR)
Drug · Behavioral
Lead sponsor
University of Utah
Other
Eligibility
25 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

INTEGRATE-D: A Pilot Test to Support Integration of Medical and Psychosocial Care for People With Type II Diabetes

NCT04461405
View directory record Official record
Conditions
Type II Diabetes, Primary Health Care, Behavioral Health
Interventions
INTEGRATE-D
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
294 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional

e-SMART/EST HIV Telehealth Intervention

NCT05278572
View directory record Official record
Conditions
Hiv, Depression
Interventions
Stress Management and Relaxation Training/Expressive Supportive Therapy (SMART/EST)
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
55 Years to 99 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Sep 7, 2026, 5:05 AM EDT
Not listed Not applicable Interventional

The Effects of Frailty on Chronic Kidney Disease

NCT02775305
View directory record Official record
Conditions
Sarcopenia, Chronic Kidney Disease
Interventions
Frail
Behavioral
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Sep 7, 2026, 5:05 AM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 7, 2026, 5:05 AM EDT
Not yet recruiting Not applicable Interventional

Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings

NCT07755137
View directory record Official record
Conditions
Autism Spectrum Disorder, Depressive Disorder, Anxiety Disorders
Interventions
CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU)
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
11 Years to 17 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional

Telephone-Based Counseling for Depression in Parkinson's Disease

NCT02505737
View directory record Official record
Conditions
Depression, Parkinson's Disease
Interventions
TH-CBT, Enhanced Usual Care
Behavioral · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
35 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available

Primary-Care Based Mindfulness Intervention

NCT03922581
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Major Depressive Disorder
Interventions
Mindfulness-Based Cognitive Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Flexibility Training for Persistent Pain: Neuroimaging Pilot (COFLEX-i)

NCT03720821
View directory record Official record
Conditions
Chronic Pain, Knee Pain Chronic, Hip Pain Chronic, Back Pain
Interventions
Cognitive Training + fMRI
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Sep 7, 2026, 5:05 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation

NCT04723745
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), PTSD
Interventions
V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief, OPTIONAL At-home Exercise Program, OPTIONAL Referral to 12-week STEP-Home, OPTIONAL Clinical Referral
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional

Young Adult Latino Testicular Cancer Survivors: a Pilot Study of Goal-Focused Emotion Regulation Therapy (GET)

NCT07615998
View directory record Official record
Conditions
Testicular Cancer
Interventions
Goal-focused Emotion-regulation Therapy
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional

Integrated Parent Training for Treating Depression in Mothers of Children With Attention Deficit Hyperactivity Disorder

NCT00316290
View directory record Official record
Conditions
Depression, Attention Deficit Disorder With Hyperactivity
Interventions
Integrated Parent Training, Behavioral Parent Training
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
6 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Sep 7, 2026, 5:05 AM EDT
Recruiting Not applicable Interventional

Mechanisms of Rumination Change in Adolescent Depression

NCT03859297
View directory record Official record
Conditions
Major Depressive Disorder, Mood Disorders
Interventions
Rumination-Focused CBT, Relaxation-based Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 17 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
3
States / cities
Columbus, Ohio • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 7, 2026, 5:05 AM EDT
Active, not recruiting Not applicable Interventional

Matching Adults to Treatments for Chronic Pain (MATCH) Study

NCT05699252
View directory record Official record
Conditions
Chronic Pain
Interventions
Cognitive Behavioral Therapy (CBT), Hypnotic Cognitive Therapy (HYP-CT), Mindfulness-Based Cognitive Therapy (MBCT)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Seattle, Washington • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 7, 2026, 5:05 AM EDT
Withdrawn No phase listed Observational

Sleep Quality, Cognitive Performance, and Computerized Cognitive Training

NCT06328140
View directory record Official record
Conditions
Bipolar Disorder, Major Depressive Disorder, Psychosis
Interventions
Lurasidone, FDA Approved antidepressant treatment
Drug
Lead sponsor
George West Mental Health Foundation d/b/a Skyland Trail
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional

Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit

NCT06420193
View directory record Official record
Conditions
Depression, Cancer, Adolescent, Young Adult, Adult
Interventions
AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
15 Years to 39 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Psychosocial Therapy and Risperidone Treatment in Work Performance in Recent-Onset Schizophrenia

NCT00333177
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive remediation training (CT), Healthy behavior training (HBT), Risperidone, administered orally (Oral Ris), Risperidone, administered via injection (RLAI)
Behavioral · Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 7, 2026, 5:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Reducing Depressive Symptoms During HCV Therapy: A Randomized Study

NCT00495768
View directory record Official record
Conditions
Hepatitis C, Depression
Interventions
Group Training
Behavioral
Lead sponsor
South Texas Veterans Health Care System
Federal
Eligibility
25 Years to 68 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 13, 2007 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional

An Attachment Based Approach for Anxiety and Depression

NCT04719780
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Emotionally Focused Therapy for Individuals, Self-Help CBT Training
Behavioral
Lead sponsor
Saint Paul University
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Sep 7, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available

Spouse READI (Resilience Education And Deployment Information) Post Deployment Telephone Support Groups

NCT01121250
View directory record Official record
Conditions
Spouses, Military Personnel, Coping Skills
Interventions
Telephone Discussion Groups, Education sessions
Behavioral
Lead sponsor
Memphis VA Medical Center
Federal
Eligibility
Female only
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 29, 2018 · Synced Sep 7, 2026, 5:05 AM EDT
Recruiting Not applicable Interventional

Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics

NCT05877885
View directory record Official record
Conditions
Major Depressive Disorder, Apathy
Interventions
Targeted Cognitive Training Intervention, General Cognitive Training Intervention
Behavioral
Lead sponsor
AdventHealth
Other
Eligibility
60 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 7, 2026, 5:05 AM EDT