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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:26 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 1,835 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Depression Intervention Clear all

Conditions: MDD, Depression
Interventions: Transcranial Magnetic Stimulation; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 75 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Communication Research
Interventions: nurse-led communication strategy; Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Suicide, Accidental Injuries, Firearm Injury
Interventions: MI FSN - Lethal Means Reduction, Scripted FSN - Lethal Means Reduction, General Firearm Safety Intervention - General Firearm Safety, General Firearm Comparison - General Firearm Safety; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Kotzebue, Alaska

Conditions: Depression Symptoms
Interventions: Creativity Camp; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 12 Years to 17 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Hepatitis C, Depression
Interventions: Depression collaborative care model; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 309 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 4
States / cities: Little Rock, Arkansas • West Los Angeles, California • St Louis, Missouri + 1 more

Conditions: Depression
Interventions: Interactive Media-Based Problems Solving Treatment; Behavioral
Lead sponsor: William Stone; Other
Eligibility: 18 Years to 80 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Anxiety
Interventions: Alpha Stim device, Sham device; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 64 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Sarcopenia, Chronic Kidney Disease
Interventions: Frail; Behavioral
Lead sponsor: San Francisco Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 100 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Major Depressive Disorder
Interventions: Digital CBT, Waitlist; Device · Other
Lead sponsor: Big Health Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression
Interventions: Mindfulness maintenance program; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression
Interventions: LENA with Feedback, LENA no feedback; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 99 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Depression
Interventions: Genomind®Professional PGx Express TM; Genetic
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 89 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Anxiety, Depression
Interventions: Brief Behavioral Therapy; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 8 Years to 17 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: TBI (Traumatic Brain Injury)
Interventions: Venlafaxine; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina, STEMI, NSTEMI - Non-ST Segment Elevation MI
Interventions: MBCT intervention for ACS patients; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 35 Years to 85 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Anxiety
Interventions: Lumen Coached PST Intervention., Human Coached PST Intervention., Optional (delayed) Lumen Coached PST (Waitlist control).; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Depression, HIV Infections
Interventions: Telephone-based CBT, Enhanced Usual Care; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Stress Disorders, Post-Traumatic, Anxiety, Depression
Interventions: Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT); Behavioral
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 7 Years to 14 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: HIV/AIDS, Depression, Anxiety, Post-traumatic Stress Disorder, Substance Use Disorders
Interventions: Adapted Common Elements Treatment Approach; Behavioral
Lead sponsor: Michael J Mugavero, MD; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Depression, Parkinson's Disease
Interventions: Cognitive-behavioral therapy (CBT); Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: Not listed
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depressive Disorder
Interventions: Cognitive Behavior Therapy (CBT), Nonspecific Supportive Therapy (PBO); Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Schizophrenia, Schizophrenia and Related Disorders, Bipolar Disorder, Bipolar and Related Disorders, Major Depressive Disorder, Major Depression Severe, Ketogenic Dieting, Ketosis, Metabolic Disease, Metabolic Syndrome
Interventions: LCHF Ketogenic Diet, Diet-as-Usual (DAU); Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Treatment Resistant Depression, Major Depressive Episode, Major Depression, Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Obsessive-Compulsive Disorder
Interventions: Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine, Esketamine, Deep Transcranial Magnetic Stimulation (dTMS); Device · Drug
Lead sponsor: Mark Niciu; Other
Eligibility: 18 Years to 99 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2050
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Alzheimer Disease, Alzheimer Dementia, Alzheimer's Disease, Dementia
Interventions: Behavioral Activation, Information and Support; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 55 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: La Jolla, California

Search by objective public record fields.

Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder

Using a Nurse-Led Communication Strategy for Surrogates in the Intensive Care Unit

Family Safety Net - Aim 3: Randomized Control Trial

Measuring and Enhancing Creativity and Brain Flexibility in Adolescents With Depression

Hepatitis C Translating Initiatives for Depression Into Effective Solutions

A Computerized Intervention for Depression

The Efficacy of Cranial Electrostimulating Therapy for Depression and Anxiety Among Homeless Adults

The Effects of Frailty on Chronic Kidney Disease

Rise Study for Depression

Optimizing Mindfulness Based Cognitive Therapy (MBCT) Maintenance

Using the LENA System in Early Intervention

Individualizing Antidepressant Treatment Using Pharmacogenomics and EHR-driven Clinical Decision Support

Video-visit Behavior Therapy for Anxiety and Depression in Youth

Pharmacological Intervention in Depression After Traumatic Brain Injury

MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms

Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor(SPEAC) for Adults With Emotional Distress (Phase 2)

Telephone Based Cognitive Behavioral Therapy for HIV Related Depression

Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence

Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States

Telehealth Psychotherapy for Depression in Parkinson's Disease

Mechanisms of Emotion Regulation Underlying Successful CBT in Depression

Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling

University of Iowa Interventional Psychiatry Service Patient Registry

Alzheimer's Caregiver Coping: Mental and Physical Health