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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:35 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 1,835 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Depression Intervention Clear all

Conditions: Knee Pain Chronic
Interventions: transcranial direct current stimulation, physical therapy; Device · Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Postpartum Depression, Postpartum Anxiety, Stress
Interventions: M.Bapp, App-based parenting education; Behavioral
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression; Major Depressive Disorder
Interventions: Sleep Deprivation; Other
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Stroke, Family Caregivers
Interventions: Telephone Assessment and Skill-Building Kit (TASK II), Information, Support, and Referral (ISR); Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 21 Years and older
Enrollment: 254 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: People Living With HIV
Interventions: BHS+ORCHID; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: Not listed
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 3
States / cities: Chicago, Illinois

Conditions: Major Depressive Disorder, Epilepsy
Interventions: Neurobehavioral therapy; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Parkinson's Disease
Interventions: High-Frequency Repetitive Transcranial Magnetic Stimulation, Sham Repetitive Transcranial Magnetic Stimulation; Device
Lead sponsor: University of Florida; Other
Eligibility: 30 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Type 1 Diabetes Mellitus, Depressive Symptoms
Interventions: CATCH-IT; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 13 Years to 17 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Gynecologic Oncology Patient
Interventions: Integrated psychological care, Surveys, Blood draw, Fresh tissue from ovary; Behavioral · Other · Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Psychiatric Diagnosis
Interventions: Making Connections Intervention-Telehealth (MCI-T), Treatment as usual (TAU); Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 12 Years to 18 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression
Interventions: Peer-assisted computerized CBT, Enhanced usual care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 3
States / cities: Ann Arbor, Michigan • Battle Creek, Michigan • Detroit, Michigan

Conditions: Depression in Old Age
Interventions: On-site AE, At-home AE, Social Engagement (SE); Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 60 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Premature Birth
Interventions: Full Term EEG, Facilitated Infant Care; Other · Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 26 Weeks to 42 Weeks
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Newark, New Jersey • New York, New York

Conditions: Osteoarthritis, Knee, Hypertension
Interventions: STAR Intervention, Attention-Control; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 50 Years and older
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Opioid-use Disorder, Stress Related Disorder, Anxiety, Pain Interference
Interventions: Live-Online M-ROCC, Live-Online Control; Behavioral
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years to 70 Years
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Childhood Mental Disorder
Interventions: PCIT-ED, Parenting Wisely; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 48 Months to 83 Months
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Postpartum Depression, Intimate Partner Violence
Interventions: Case Management by Family Support Counselor (not RCT); Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: Female only
Enrollment: 173 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depressive Episode, Depression, Depressive Disorder, Depressive Disorder, Major, Depression Mild
Interventions: MEB-001; Device
Lead sponsor: Medibio Limited; Industry
Eligibility: 22 Years to 75 Years
Enrollment: 715 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 13
States / cities: Bradenton, Florida • Blaine, Minnesota • Plymouth, Minnesota + 10 more

Conditions: Chronic Illness, Chronic Pain, Depression, Comorbid Depression
Interventions: Pre-Post Feasibility; Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Anxiety, Mood
Interventions: Technology-Enabled CBT Treatment; Behavioral
Lead sponsor: Jail Education Solutions, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Eureka, Illinois • Billerica, Massachusetts

Conditions: Schizophrenia and Related Disorders
Interventions: There is no intervention; Other
Lead sponsor: Northwell Health; Other
Eligibility: 15 Years to 40 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Glen Oaks, New York

Conditions: Stroke
Interventions: SHARP coach intervention; Behavioral
Lead sponsor: Visiting Nurse Service of New York; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Type 2 Diabetes, Depression, Insulin Resistance, Obesity, Adolescent Development
Interventions: Mindfulness-Based Intervention, Cognitive-Behavioral Therapy, Health Education; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 4
States / cities: Aurora, Colorado • Fort Collins, Colorado • Washington D.C., District of Columbia + 1 more

Conditions: Anxiety Disorders
Interventions: Transdiagnostic Telenovela Intervention; Behavioral
Lead sponsor: University of Nevada, Reno; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Reno, Nevada

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Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain

Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention

Sleep/Wake Cycle and Depression: An Imaging and Treatment Study

Telephone Assessment and Skill-Building Intervention for Stroke Caregivers

A Hybrid Type II Trial of the Optimizing Resilience and Coping With HIV Through Internet Delivery in Ryan White Clinics in Chicago

Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder

Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Apathy in Parkinson's Disease

Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms in Adolescents With Type 1 Diabetes Mellitus

Psychological Services Integration in Gynecological Oncology Clinics

Impact of Telehealth on Engagement in Psychotherapy and/or Medication Treatment

Veteran Peer-Assisted Computerized Cognitive Behavioral Therapy for Depression

Fitness for Brain Optimization for Late-Life Depression

Family Nurture Intervention in the CHoNJ NICU

Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension

Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)

Trial of PCIT-ED in School for Preschoolers in Poverty

Case Management Study for Postpartum Depression and Intimate Partner Violence

Sleep Signal Analysis for Current Major Depressive Episode (SAMDE)

Treating Comorbid Depression During Care Transitions Using Relational Agents

Technology Enabled Mental Health Intervention for Individuals in the Criminal Justice System

Linguistic Predictors of Outcomes in Psychosis

Stroke Home Health Aide Recovery Program (SHARP) Pilot

Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents

Reducing Mental Health Disparities Among Latinxs With a Telenovela Intervention