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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 313–336 of 1,835 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Depression Intervention Clear all

Conditions: Distress, Caregiver
Interventions: Resourcefulness Training, Biofeedback training, Bipolar Education; Behavioral
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 120 Years
Enrollment: 310 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Major Depressive Disorder
Interventions: gammaCore™; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 75 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Depression, Hemodialysis-Induced Symptom
Interventions: Fluoxetine; Drug
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Overdose
Interventions: Not listed
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Head and Neck Cancer
Interventions: geriatric co-management, geriatric guided supportive care; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 65 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 6
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 3 more

Conditions: Depression, HIV
Interventions: Beating the Blues; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 2
States / cities: Indianapolis, Indiana

Conditions: Treatment Resistant Depression
Interventions: Aerobic Exercise, Video Watching; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obesity, Anxiety Sensitivity, Eating, Physical Activity
Interventions: Anxiety Sensitivity Training, Health Control; Other
Lead sponsor: University of Houston; Other
Eligibility: 18 Years and older
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Gastrointestinal Disorders, Functional
Interventions: Online Cognitive Behavior Therapy, Online Education; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 11 Years to 17 Years
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: PrEP Uptake Experiences, PrEP Adherence Experiences, Mental Health Symptoms
Interventions: Trans STAIR, PrEP Well; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depression
Interventions: SBIRT, Referral as Usual; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 505 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: New York, New York

Conditions: Stress Disorders, Post-Traumatic, Depression, Anxiety
Interventions: Family Care Rituals; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 452 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Chicago, Illinois • Providence, Rhode Island

Conditions: Anxiety, Depression, Insomnia, Sleep Quality
Interventions: Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator); Device
Lead sponsor: Christina Murphey, RN, PhD; Individual
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Austin, Texas • Corpus Christi, Texas

Conditions: Depression, Postpartum
Interventions: Share, Self-Directed; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older · Female only
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 3
States / cities: Chicago, Illinois • Iowa City, Iowa

Conditions: Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With No Loss of Consciousness
Interventions: Cognitive Rehab, Brainworks, Informational Handout/Provider Visits; Behavioral
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Cannabis Use Disorder, Anxiety, Depression, Anxiety, Depression - Major Depressive Disorder
Interventions: Therabot-CALM; Device
Lead sponsor: Trustees of Dartmouth College; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Depressive Disorder, Major
Interventions: Navigated Transcranial Magnetic Stimulation; Device
Lead sponsor: Magstim; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 2
States / cities: Atlanta, Georgia • Dunwoody, Georgia

Conditions: Depression, Unipolar
Interventions: Single Session Psychotherapy Intervention; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Smoking Cessation
Interventions: Bupropion, Nicotine patch, Varenicline; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 223 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Stanford, California

Conditions: Breast Cancer
Interventions: Distress screening; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 1,436 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 6
States / cities: Anaheim, California • Baldwin Park, California • Harbor City, California + 2 more

Conditions: Migraine, Depression
Interventions: ACT-IM; Behavioral
Lead sponsor: Lilian N. Dindo; Other
Eligibility: 18 Years to 75 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Depression, Burnout, Professional
Interventions: Psilocybin, Mindfulness-Based Stress Reduction (MBSR); Drug · Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 25 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Fibromyalgia
Interventions: CES device, sham device; Device
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Mental Health Issue, Breast Cancer
Interventions: Digital Micro-Interventions; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older · Female only
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

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Tailored Health Self-Management Interventions for Highly Distressed Family Caregivers

Vagal Nerve Stimulation for Treatment Resistant Major Depression

Identifying and Treating Depression in Hemodialysis Patients

Overdose Prevention Centers and Behavioral Health

A Study Comparing Geriatric Co-Management With Geriatric Guided Supportive Care in Older Patients Receiving Chemoradiation Therapy for Their Head and Neck Cancer

Depression Therapy to Improve Cardiovascular Risk in HIV

Exercise to Augment TMS in Those With Treatment Resistant Depression

Computer-Delivered Intervention for Individuals With Obesity and Elevated Anxiety Sensitivity

Web-based Management of Pediatric Functional Abdominal Pain

Trans STAIR: Implementing an Evidence Based Trauma Treatment With Community Led PrEP Navigation

Depression Screening in Black Churches

Prospective Evaluation of Family Care Rituals in the ICU

Efficacy of CES in New Mothers During the Post Partum Period

Online Collaborative Learning Intervention to Prevent Perinatal Depression

The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury

Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Coil Positioning in Navigated Transcranial Magnetic Stimulation Feasibility in Depression Patients Trial

Psychotherapy Feasibility Pilot of the Carolina Recovery From Depression Protocol

Extended Treatment for Smoking Cessation

Implementing Systematic Distress Screening in Breast Cancer

Brief Behavioral Intervention for Comorbid Migraine and Depression

PAPR: PAP + MBSR for Front-line Healthcare Provider COVID-19 Related Burnout

Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia

A Pre-post Pilot of a Smartphone Intervention