Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:23 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 1,835 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Depression Intervention Clear all

Conditions: Depression
Interventions: dCBI, Treatment as Usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 16 Years to 22 Years
Enrollment: 185 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 3
States / cities: San Diego, California • Boston, Massachusetts • Pittsburgh, Pennsylvania

Conditions: Cardiovascular Diseases, Coronary Disease, Heart Diseases, Depression
Interventions: Psychoeducation; Treatment recommendations, Pharmacotherapy, Usual Care; Behavioral · Drug · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 100 Years
Enrollment: 453 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Anhedonia, Depression
Interventions: Not listed
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Mental Health Disorder, Social Isolation, Stigma, Social
Interventions: Young Women of Today; Behavioral
Lead sponsor: West Chester University of Pennsylvania; Other
Eligibility: 14 Years to 18 Years · Female only
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: West Chester, Pennsylvania

Conditions: Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia, Sleep Disorder, Sleep Initiation and Maintenance Disorders, Disorders of Initiating and Maintaining Sleep, Anxiety, Depression
Interventions: Brief treatment for Insomnia, Sleep Monitoring; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Subjective Cognitive Decline, Depression in Old Age
Interventions: PeersCOG; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 60 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stimulant Use, Depression
Interventions: Accelerated Repetitive Transcranial Magnetic Stimulation; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Tobacco Use Cessation
Interventions: Path2Quit - culturally specific text message intervention; Behavioral
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: PROMs, Waitlist, Telemedicine, Mental Health Disorder, Psychiatric or Mood Diseases or Conditions
Interventions: Patient-rated outcome measures and educational videos; Behavioral
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Traumatic Brain Injury, Chronic Pain, Post Traumatic Stress Disorder, Depression, Anxiety
Interventions: ACT on Life, Education, Resources, and Support; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 176 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Type 2 Diabetes Mellitus, Depression
Interventions: Adherence Intervention; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 30 Years and older
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Rheumatoid Arthritis
Interventions: Cognitive Behavioral Therapy, Tai Chi Chih, Health Education Seminar; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depression, Obesity
Interventions: Accept Yourself!, Weight Watchers; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Anxiety Disorders, Depression, Psychological Distress, Tobacco Dependence, Smoking, Tobacco, Smoking, Cigarette
Interventions: PFI for Smoking & Distress Tolerance, PFI for Smoking Only; Behavioral
Lead sponsor: University of Houston; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression
Interventions: BA (brief advice), SHE (supervised and home-based exercise), HE (health education), CBEX (cognitive-behavioral sessions focused on increasing and maintaining exercise); Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Anxiety, Depression, Malignant Neoplasm
Interventions: Interview, Meditation Therapy, Quality-of-Life Assessment, Supportive Care; Other · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Mood Disorders, Anxiety Disorders
Interventions: Cognitive behavioral therapy with AI, Cognitive behavioral therapy; Behavioral
Lead sponsor: Eleos Health; Industry
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Joplin, Missouri

Conditions: Depression Mild, Depression Moderate
Interventions: El Buen Consejo Móvil- Group (EBCM-G), El Buen Consejo Móvil- Individual (EBCM-I); Behavioral
Lead sponsor: Northern Illinois University; Other
Eligibility: 18 Years to 110 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: DeKalb, Illinois

Conditions: Major Depressive Episode
Interventions: Text Messaging Intervention; Other
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 16 Years to 45 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Osteoarthritis, Knee
Interventions: Positive Minds, Strong Joints; Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 50 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression, Alcohol Abuse, Drinking, College, Alcohol Drinking, Alcohol; Harmful Use, Social Stigma, Social Norms, Social Responsibility, Social Behavior, Empathy, Coping Skills, Coping Behavior
Interventions: Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS); Behavioral
Lead sponsor: University of New Hampshire; Other
Eligibility: 18 Years to 24 Years
Enrollment: 1,268 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Durham, New Hampshire

Conditions: Sleep, Pain, Anxiety, Depression, Fatigue
Interventions: Feedback Group; Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Nicotine Dependence, Symptoms of Anxiety, HIV
Interventions: Integrated cognitive-behavioral therapy for smoking cessation and anxiety, Control; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depressive Disorder
Interventions: MBCT Intervention; Behavioral
Lead sponsor: Clemson University; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Clemson, South Carolina • Greenville, South Carolina

Search by objective public record fields.

Study to Compare the Use of a Behavioral Health App Versus Care As Usual for 16-22 Year Olds with Depression

Effectiveness of Depression Treatment Following Coronary Artery Bypass Surgery

A Neurobiological Model of Anhedonia

Peer Support Intervention to Mitigate Social Isolation and Stigma of Adolescent Motherhood in Zimbabwe

Heart Failure Insomnia Treatment Study

Developing a Peer Support Intervention for Depression in SCD

Accelerated rTMS for Substance Use Disorder and Depression

Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers

Effectiveness of Telepsychiatry With Randomized Waitlist Control Utilizing Patient Reported Outcome Measures

One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change

Integrating Depression Services Into DM Management

Cognitive-Behavioral Therapy and Tai Chi Chih for Patients With Rheumatoid Arthritis

Health At Every Size and Acceptance and Commitment Therapy vs. Behavioral Weight Loss for Obesity and Depression in Women

Personalized Feedback for Distress Intolerant Smokers

Initiating and Maintaining Physical Activity in Depressed Individuals

Meditation Therapy in Improving Anxiety and Depression in Cancer Patients With Psychosocial Distress

Optimizing Behavioral Healthcare Delivery Through Technology

Treatment of Depression Using a Mobile Application in the Dominican Republic

A Text Messaging Intervention to Reduce Perinatal Depression Risk

Positive Minds Strong Joints for Knee Osteoarthritis

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

PROMIS Measures in Primary Care Practice

Integrated Treatment for Smoking Cessation & Anxiety in People With HIV

Virtual Mindfulness Training for Adults With History of Depression