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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:08 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 481–504 of 1,835 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Depression Intervention Clear all

Conditions: Facial Pain
Interventions: TMS, sham TMS coil; Device
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years to 100 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Post Traumatic Stress Disorder, Depression, Violence
Interventions: BSHAPE, Control (general wellness); Behavioral · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 676 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Major Depressive Disorder
Interventions: Psilocybin; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 75 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depression, Breastfeeding
Interventions: Sunnyside, Sunnyside Plus; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Anxiety, Depression, Depression/Anxiety
Interventions: Therapy, Therapy + Adhere.ly; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Major Depressive Disorder
Interventions: tDCS intervention applied by Starstim device; Device
Lead sponsor: Neuroelectrics Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 4
States / cities: Coral Springs, Florida • Miami, Florida • Snellville, Georgia + 1 more

Conditions: Depression, Loneliness, Relation, Interpersonal, Covid19
Interventions: Intervention; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 1,765 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression, Anxiety, Stress
Interventions: Space from Depression, Space from Anxiety, Space from Stress; Other
Lead sponsor: Silver Cloud Health; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Anxiety, Depression, Breast Cancer
Interventions: Mindfulness Based Cognitive Therapy, Treatment as Usual; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Cancer
Interventions: management of therapy complications, massage therapy, pain therapy, psychosocial assessment and care, quality-of-life assessment; Procedure
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 120 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: HIV/AIDS
Interventions: The BRIDGES Project Intervention; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: San Diego, California

Conditions: Mood Disorders, Anxiety Disorders
Interventions: 10 sessions of ASGI; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 55 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Major Depression Disorder
Interventions: Adjunct brexpiprazole, ADT; Drug
Lead sponsor: H. Lundbeck A/S; Industry
Eligibility: 65 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 13
States / cities: Arcadia, California • Miami, Florida • Orlando, Florida + 9 more

Conditions: Postpartum Depression (PPD), Self-Efficacy, Parental Anxiety, Engagement, Patient, Usability, Length of Stay
Interventions: VoiceLove mobile phone application; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Depression
Interventions: Comprehensive Mental Health Services and Supports; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 16 Years to 24 Years
Enrollment: 782 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Arm Illness
Interventions: PROMIS Upper Extremity Function, Pain intensity, PROMIS depression, Positive affect negative affect scale (PANAS), standard PCS, positively-adjusted version of the PCS; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression / Major Depressive Disorder, Anxiety
Interventions: Not listed
Lead sponsor: Kintsugi Mindful Wellness, Inc.; Industry
Eligibility: Not listed
Enrollment: 50,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Depression, Mental Disorder in Adolescence
Interventions: Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 13 Years to 18 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 6
States / cities: Chicago, Illinois • Glenview, Illinois • Park Ridge, Illinois + 1 more

Conditions: Depression
Interventions: Guided Imagery and Mindfulness, Facilitated Discussion; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 45 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression
Interventions: Pramipexole; Drug
Lead sponsor: Stanford University; Other
Eligibility: 20 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Stanford, California

Conditions: Sleep, Postpartum Depression, Pregnancy Related, Insomnia, Sleep Deprivation, Sleep Hygiene, Sleep Disturbance
Interventions: Education about behavioral strategies to improve sleep; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years to 99 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Major Depressive Disorder, Recurrent, in Remission, Depressive Symptoms
Interventions: Usual Depression Care, Mindful Mood Balance; Behavioral
Lead sponsor: University of Toronto; Other
Eligibility: 18 Years and older
Enrollment: 460 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Preterm Birth
Interventions: Implementation of social determinants of health screening and referral; Other
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older · Female only
Enrollment: 882 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 7
States / cities: Denver, Colorado • Jacksonville, Florida • Detroit, Michigan + 4 more

Conditions: Major Depressive Disorder
Interventions: Standard Quality Improvement, Patient-centered Intervention; Procedure
Lead sponsor: Agency for Healthcare Research and Quality (AHRQ); Federal
Eligibility: 18 Years to 75 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 5
States / cities: Wilmington, Delaware • Baltimore, Maryland

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Transcranial Magnetic Stimulation (TMS) for Trigeminal Neuralgia

Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study

Effects of Psilocybin in Major Depressive Disorder

Online Intervention to Prevent Perinatal Depression and Promote Breastfeeding

Improving Adherence to Homework During Therapy

Home-based Transcranial Direct Current Stimulation (tDCS) for Major Depressive Disorders (MDD)

A Smartphone Intervention for Relational and Mental Well Being

Effectiveness and Acceptability of Internet-delivered Treatment for Depression, Anxiety and Stress

Mindfulness for Breast Cancer

Massage Therapy in Treating the Symptoms of Patients With Locally Advanced or Metastatic Cancer

The BRIDGES Project: Bridging Resources to Engage Women in Integrated HIV Care and Support Services

Anti-stigma Intervention for Chinese American Older Adults

Evaluation of the Safety of Adjunct Brexpiprazole in Elderly Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Treatment

NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)

Addressing Mental Health in African American Job Training Adolescents and Young Adults

The Effect of Questionnaire Content on Measures of Pain Intensity, Magnitude of Disability, and Symptoms of Depression in Patients With Arm Illness

Activating Voice Journaling for Mental Health With Voice Biomarkers

The PATHway Study: Primary Care Based Depression Prevention in Adolescents

Group Therapy for Depressed Dementia Caregivers

Imaging the Nucleus Accumbens in Major Depressed Patients 'Treated With Pramipexole

The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

Reducing Residual Depressive Symptoms With Web-based Mindful Mood Balance

The Social Determinants of Health Screening and Referral Project

Patient-Centered Depression Care for African Americans