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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:25 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 1,835 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Depression Intervention Clear all

Conditions: Cardiovascular Diseases
Interventions: Attention Control, Gratitude Journaling; Behavioral
Lead sponsor: Martha Biddle; Other
Eligibility: 18 Years to 100 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
Interventions: Autism-adapted Group Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 11 Years to 17 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Depression, Postpartum
Interventions: Survival Skills for Moms with New Babies; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2001
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression, Anxiety
Interventions: Sanvello (app); Device
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 18 Years and older
Enrollment: 4,607 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Depression, Anxiety, Anger
Interventions: Psychoeducational intervention; Behavioral
Lead sponsor: Loyola University; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Sickle Cell Disease
Interventions: Heart Rate Variability Biofeedback; Behavioral
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 10 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Depression - Major Depressive Disorder, Cannabis Use Disorder, Mental Disorder
Interventions: Amplification of Positivity - Cannabis Use (AMP-C); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cognitive Deficits, Proprioceptive Disorders
Interventions: Sensory Organization Test, Biomarkers, Conners' Adult ADHD Rating Scale (CAARS), Depression Scale, Cognitive Assessment; Other · Genetic
Lead sponsor: New York Institute of Technology; Other
Eligibility: 40 Years to 80 Years · Male only
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Old Westbury, New York

Conditions: Depression
Interventions: TIP; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 65 Years and older
Enrollment: 231 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Ann Arbor, Michigan • New York, New York

Conditions: Inflammatory Bowel Diseases, Anxiety, Depression, Ulcerative Colitis, Crohn Disease
Interventions: Mental health support session; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depression, Asthma, Urticaria
Interventions: Brief Behavioral Activation Intervention; Behavioral
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years to 64 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Heart Failure
Interventions: Brief Cognitive Therapy Intervention; Behavioral
Lead sponsor: Rebecca L. Dekker, PhD, RN, APRN; Other
Eligibility: 21 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Cancer, Depression
Interventions: Technology-Enabled Tailored Referral; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Stroke, Depression, Depressive Symptoms, Post-stroke Depression
Interventions: Dyadic (couples-based) positive psychology intervention; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Depression
Interventions: bCBT; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 2
States / cities: Oklahoma City, Oklahoma • Houston, Texas

Conditions: Depression
Interventions: Family Cognitive Behavioral Prevention, Written information; Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 9 Years to 15 Years
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2023
U.S. locations: 2
States / cities: San Diego, California • Nashville, Tennessee

Conditions: Sleep, Sleep Disturbance, Insufficient Sleep
Interventions: SPP, Sleep Psychoeducation; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 18 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression
Interventions: Behavioral Activation Therapy, Treatment as Usual- Psychotherapy; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 11 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression, Major Depressive Disorder, PTSD, Anxiety
Interventions: Iyengar Yoga, Walking; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Mental Health Disorder
Interventions: Mindful My Way; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 65 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Child Development
Interventions: Training for ACEs and study procedures, Training on study procedures; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Chamblee, Georgia

Conditions: Self-Injurious Behavior, Deliberate Self-Harm
Interventions: Not listed
Lead sponsor: University of Minnesota; Other
Eligibility: 12 Years to 16 Years · Female only
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2023
U.S. locations: 3
States / cities: Minneapolis, Minnesota

Conditions: Chronic Pain, Chronic Pain (Back / Neck)
Interventions: No Intervention: Observational Cohort; Other
Lead sponsor: Evidence In Motion; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Story City, Iowa

Conditions: Depression, Adolescent Behavior, Depressive Symptoms
Interventions: Volunteer experience; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 14 Years to 20 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Winston-Salem, North Carolina

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Gratitude Intervention for Cardiac Rehabilitation Patients

Group Depression Treatment for Autistic Youth

Prevention of Postpartum Depression in Low-Income Women

Testing a Digital Health Intervention App for Depression and Anxiety

A Pychoeducational Intervention for Women With Diabetes

HRV-B for Symptom Management in Sickle Cell Patients

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Effects of Multiple Concussions in Retired NHL Players

Personalized Antidepressant Adherence Strategies For Depressed Elders

Digital Support for Mental Health Intervention in Patients With Inflammatory Bowel Disease

Brief Behavioral Activation Intervention for Depressed Asthma and Urticaria Patients

Helping Others Toward Positive Emotions in People With Heart Failure

Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors

Testing a Positive Psychology-based Intervention for Couples Coping With Stroke

Effectiveness and Implementation of Brief Cognitive Behavioral Therapy in CBOCs

A Family Depression Prevention Program

Sleep Promotion Program Primary Care

Behavioral Activation With Depressed Adolescents

The Treatment of Depression With Yoga and Walking

e-Mindfulness for Depression in Older Adults

Caregiver Adverse Childhood Experiences (ACEs) in Pediatric Primary Care

A Study Examining Adolescents With Non-Suicidal Self-Injury

Chronic Pain, Emotions and Professional Football

Volunteering as an Intervention to Reduce Depression Among Adolescents