Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:33 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 1,835 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Depression Intervention Clear all

Conditions: Hematopoietic/Lymphoid Cancer
Interventions: Paced respiration as part of PEPRR, PEPRR; Device · Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 298 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Aurora, Colorado • Denver, Colorado

Conditions: Parent-Child Relations
Interventions: Family Foundations Coparenting Program; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 18 Years and older
Enrollment: 497 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Parkinson Disease, Depression
Interventions: OnabotulinumtoxinA, Control; Biological
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Psychological Distress, Depression, PTSD, Anxiety
Interventions: Personalized Support for Progress (PSP), Tailored Referral (TR); Other
Lead sponsor: Syracuse VA Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Syracuse, New York • Houston, Texas

Conditions: Major Depressive Disorder
Interventions: Approach-positive AAT, Control AAT; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: San Diego, California

Conditions: Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
Interventions: Stepped Care Management; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 14 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression, Depressive Disorder
Interventions: Transcranial Direct Current Stimulation, Mindful Breathing, Sham; Device · Behavioral · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 16 Years to 24 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Anxiety Disorders, Depressive Disorder, Eating Disorders
Interventions: SilverCloud Health Intervention; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 6,205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 4
States / cities: Palo Alto, California • Ann Arbor, Michigan • St Louis, Missouri + 1 more

Conditions: Breast Cancer
Interventions: questionnaires; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Survivorship, Cancer, Depression, Anxiety
Interventions: Telephone interview, Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Anxiety Disorders and Symptoms, Depression, Bipolar Disorder, Symptoms
Interventions: Personalized MAYA Mobile App, General MAYA Mobile App; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Stroke
Interventions: Modified cognitive behavioral therapy plus problem-solving, usual care; Behavioral · Other
Lead sponsor: University of Washington; Other
Eligibility: 21 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Postpartum Depression, Infant Development, Rhythm; Sleep
Interventions: Resources for Postpartum Parenting; Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Depressive Symptoms
Interventions: Acceptance and commitment therapy (ACT), Psychoeducation; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Long COVID, Long COVID-19, Hypersomnia, Sleep Disturbance
Interventions: Modafinil, Modafinil Placebo, Solriamfetol, Solriamfetol Placebo, Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo; Drug · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 830 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 47
States / cities: Phoenix, Arizona • Tucson, Arizona • Palo Alto, California + 31 more

Conditions: Infant Behavior, Child Behavior, Parenting, Child Rearing, Depression, Personal Satisfaction, Behavioral Symptoms, Social Control, Informal
Interventions: Video Interaction Project, Family Check Up; Behavioral
Lead sponsor: New York University; Other
Eligibility: 0 Years and older
Enrollment: 403 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2025
U.S. locations: 2
States / cities: New York, New York • Pittsburgh, Pennsylvania

Conditions: Weight Stigma
Interventions: Health at Every Size in Obstetrics; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Anxiety, Depressive Symptoms, Sleep Disturbance, Recurrent Disease, Fatigue, Quality of Life, Cancer
Interventions: Severe Anxiety/depression: High Intensity Stepped Care, Moderate Anxiety/depression: Low Intensity Stepped care, Enhanced Usual Care Control; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 166
States / cities: Fort Smith, Arkansas • Fresno, California • Modesto, California + 129 more

Conditions: Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
Interventions: Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC); Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Breast Cancer, Postmenopausal
Interventions: Dual x-ray absorptiometry (DXA), Blood draw, Questionnaire; Procedure · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 40 Years and older · Female only
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Depression
Interventions: Happify Breather App; Device
Lead sponsor: Donna Schuman; Other
Eligibility: 18 Years to 45 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Bipolar Depression
Interventions: Ketogenic Diet; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Major Depression
Interventions: Pharmacogenetic Test; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 1,944 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 24
States / cities: North Little Rock, Arkansas • Palo Alto, California • San Francisco, California + 21 more

Conditions: Cognitive Impairment, no Dementia (CIND)
Interventions: Aerobic Exercise, DASH diet, Health education control; Behavioral · Other
Lead sponsor: Duke University; Other
Eligibility: 55 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Search by objective public record fields.

Stress Management Intervention for Caregivers of Patients Undergoing Bone Marrow Transplant (BMT)

Family Foundations Coparenting Pilot Trial

Trial of OnabotulinumtoxinA for Depression in Parkinson Disease

Peer Intervention to Improve Access Among Rural Women Veterans With Psychological Distress and Unmet Social Needs

The Neurobiology of Approach Avoidance Training in Depression

Trauma Survivors Outcomes and Support Study IV

Mindful Breathing and tDCS for Depression

Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations

Investigating Mechanisms to Explain Age Associated Differences in Quality of Life Among Breast Cancer Patients

Telephone-Based Intervention to Treat Depression and Anxiety in Hispanic Cancer Survivors

Personalized Mobile Cognitive Behavioral Therapy Application

Psychosocial/Behavioral Intervention in Post-Stroke Depression

Social Circumstances, Parenting Techniques, and Infant Development

A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia

RECOVER-SLEEP: Platform Protocol

Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics

Adapting a Health at Every Size Intervention to Obstetric Care

Stepped-Care Telehealth for Distress in Cancer Survivors

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

Effect of Aromatase Inhibitors on Bones and Genes

Depression, Trauma, and Health: Efficacy of an mHealth App for Symptom Self-Management in College Students

Ketogenic Intervention for Bipolar Depression

PRIME Care (PRecision Medicine In MEntal Health Care)

ENLIGHTEN: Exercise and NutritionaL Interventions for coGnitive and Cardiovascular HealTh ENhancement