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ClinicalTrials.gov public records Last synced Oct 28, 2026, 1:37 PM EDT

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Showing 769–792 of 4,364 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Depression Scale Clear all
Completed No phase listed Observational Accepts healthy volunteers

Effects of Barefoot Running vs. in Shoes on Physiology and Mood

NCT01733381
View directory record Official record
Conditions
Autonomic Nervous System (ANS) Functioning and Mood State
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Phase 3 Interventional

Safety Study of F2695 SR in Major Depressive Disorder

NCT01034267
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
F2695 SR
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 80 Years
Enrollment
828 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
68
States / cities
Dothan, Alabama • Scottsdale, Arizona • Beverly Hills, California + 57 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2012 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Diabetes Prevention and Control in the Workplace: A Pilot Study

NCT00739336
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Diabetes Prevention and Control
Behavioral
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Oct 28, 2026, 1:37 PM EDT
Not listed Not applicable Interventional

Engage for Late-Life Depression and Comorbid Executive Dysfunction

NCT05356611
View directory record Official record
Conditions
Depression in Old Age, Psychotherapy, Mild Cognitive Impairment, Executive Dysfunction
Interventions
Engage
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

NCT04948944
View directory record Official record
Conditions
Depression, Anxiety and Fear
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 28, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional

Biomarkers of Depression and Treatment Response

NCT04581902
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
rTMS therapy
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Insomnia in Stable Heart Failure

NCT02827799
View directory record Official record
Conditions
Heart Failure, Insomnia, Cardiomyopathy
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Heart Failure Self-Management Education
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 28, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanisms of Behavioral Activation (BA)

NCT05548244
View directory record Official record
Conditions
Depression
Interventions
Behavioral Activation Therapy, Baseline assessment procedures
Behavioral
Lead sponsor
Emory University
Other
Eligibility
15 Years to 17 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Phase 4 Interventional

A Preliminary Study of the Effectiveness and Tolerability of Aripiprazole in Bipolar Depression

NCT00363337
View directory record Official record
Conditions
Bipolar Depression
Interventions
aripiprazole
Drug
Lead sponsor
Lindner Center of HOPE
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 22, 2011 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional

Novel Behavioral Intervention to Enhance Social Connections in Anxiety and Depression

NCT03196544
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression
Interventions
Social Approach Training (5 sessions), Social Approach Training (10 sessions)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 55 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2020 · Synced Oct 28, 2026, 1:37 PM EDT
Completed No phase listed Observational

Studying Pain and Symptom Distress in Patients With Advanced Colon Cancer, Rectal Cancer, Pancreatic Cancer, or Liver Cancer

NCT00950144
View directory record Official record
Conditions
Colorectal Cancer, Depression, Fatigue, Liver Cancer, Pain, Pancreatic Cancer
Interventions
medical chart review, questionnaire administration, study of socioeconomic and demographic variables, quality-of-life assessment
Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2011 · Synced Oct 28, 2026, 1:37 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Investigation of Neuro-hormonal Mechanisms of Hunger, Fullness and Obesity.

NCT01008371
View directory record Official record
Conditions
Obesity, Gastric Emptying, Anxiety, Depression, Panic Disorder
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2013 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Phase 4 Interventional Results available

Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression

NCT00824044
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Cognitive Behavioral Therapy (CBT), Escitalopram
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2018 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Phase 3 Interventional

Depression Study In Elderly Patients

NCT00067444
View directory record Official record
Conditions
Depressive Disorder, Major, Major Depressive Disorder (MDD)
Interventions
Paroxetine CR
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
60 Years and older
Enrollment
560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
46
States / cities
Little Rock, Arkansas • Anaheim, California • Beverly Hills, California + 40 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2016 · Synced Oct 28, 2026, 1:37 PM EDT
Active, not recruiting Not applicable Interventional

Creating a Healthy L.I.F.E: Lifestyle Interventions For Epilepsy

NCT05283200
View directory record Official record
Conditions
Lifestyle
Interventions
Yoga, Cognitive Behavioral Therapy, Music
Behavioral
Lead sponsor
Imad Najm MD
Other
Eligibility
18 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 28, 2026, 1:37 PM EDT
Not yet recruiting Not applicable Interventional

Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching

NCT07195292
View directory record Official record
Conditions
Hearing Disability, Depression, Mobility Disability
Interventions
Sham Digital Program - General health education and interactive quizzes unrelated to depression or CBT., Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
Device
Lead sponsor
Toivoa Inc
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Dover, Delaware • East Orange, New Jersey • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional

A Hybrid Type II Trial of the Optimizing Resilience and Coping With HIV Through Internet Delivery in Ryan White Clinics in Chicago

NCT05123144
View directory record Official record
Conditions
People Living With HIV
Interventions
BHS+ORCHID
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Phase 4 Interventional

Medications for the Treatment of Dysthymic Disorder and Double Depression

NCT00234312
View directory record Official record
Conditions
Depression, Dysthymia
Interventions
escitalopram and sertraline
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Oct 28, 2026, 1:37 PM EDT
Not listed Not applicable Interventional

Reducing Mental Health Disparities Among Latinxs With a Telenovela Intervention

NCT06163599
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Transdiagnostic Telenovela Intervention
Behavioral
Lead sponsor
University of Nevada, Reno
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional

Mindfulness for Breast Cancer

NCT02647216
View directory record Official record
Conditions
Anxiety, Depression, Breast Cancer
Interventions
Mindfulness Based Cognitive Therapy, Treatment as Usual
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional

Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI

NCT00409058
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Brain Edema, Craniocerebral Trauma, Hematoma, Brain Concussion
Interventions
Teen Online Problem Solving
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Cincinnati, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 28, 2014 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Loneliness and Health Outcomes in the High Need Population

NCT05484258
View directory record Official record
Conditions
Anxiety, Loneliness, Depression, Alcohol Use Disorder, Utilization, Health Care
Interventions
Shared Medical Visit
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 28, 2026, 1:37 PM EDT
Not listed Not applicable Interventional

Peer Intervention to Improve Access Among Rural Women Veterans With Psychological Distress and Unmet Social Needs

NCT05477706
View directory record Official record
Conditions
Psychological Distress, Depression, PTSD, Anxiety
Interventions
Personalized Support for Progress (PSP), Tailored Referral (TR)
Other
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Syracuse, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Oct 28, 2026, 1:37 PM EDT
Completed Not applicable Interventional

Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial

NCT01492348
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Depression
Interventions
STEPS UP, OUC
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
6
States / cities
Fort Carson, Colorado • Fort Stewart, Georgia • Fort Campbell, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Oct 28, 2026, 1:37 PM EDT