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ClinicalTrials.gov public records Last synced Oct 23, 2026, 7:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 4,357 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Depression Scale Clear all
Completed Not applicable Interventional

Management of Depression and Social Isolation in Older Adults With Dementia With Home-based Telehealth Delivered Behavioral Activation + Caregiver Facilitation.

NCT04915040
View directory record Official record
Conditions
Depression
Interventions
Behavioral Activation for Depression
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 23, 2026, 7:50 AM EDT
Recruiting Phase 3 Interventional

Brexanolone Lifting Outcomes Of Moms

NCT07822321
View directory record Official record
Conditions
Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression, Post-Natal Depression, Peripartum Depression
Interventions
LPCN 1154A, Placebo
Drug
Lead sponsor
Lipocine Inc.
Industry
Eligibility
15 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
16
States / cities
Tucson, Arizona • Canoga Park, California • Walnut Creek, California + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Phase 2 Interventional Results available

Preventing Postpartum Depression With Intranasal Oxytocin

NCT02505984
View directory record Official record
Conditions
Depression, Postpartum, Anxiety
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 23, 2026, 7:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Self Focus in Bipolar Disorder: A Functional Magnetic Resonance Imaging (fMRI) Study

NCT02253225
View directory record Official record
Conditions
Bipolar Disorder, Major Depression, Rumination
Interventions
Functional Magnetic Resonance Imaging (fMRI)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Not applicable Interventional

Predictors of Response to Treatment for Depression

NCT03154008
View directory record Official record
Conditions
Adolescent Depression, Depression
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
14 Years to 18 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 23, 2020 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Great Plains Internet Wellness Study for Aging

NCT04461184
View directory record Official record
Conditions
Internet Based Wellness Program, Obesity, Adult Population
Interventions
Internet Wellness Intervention for Aging
Behavioral
Lead sponsor
North Dakota State University
Other
Eligibility
65 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Phase 1 Interventional Results available

Preventing Depression in the Children of Depressed African American Mothers

NCT00904917
View directory record Official record
Conditions
Depression
Interventions
Prevention Intervention Project, Psychoeducation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 14 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2014 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Risk After an Adverse Pregnancy Outcome

NCT01182363
View directory record Official record
Conditions
Maternal Depression
Interventions
Project Solve Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Female only
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
4
States / cities
Boston, Massachusetts • Natick, Massachusetts • Quincy, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neural Components Underlying the Treatment of Adolescent Depression

NCT01717508
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 23, 2026, 7:50 AM EDT
Recruiting Phase 2 Interventional

5-HTP and Creatine for Depression R33 Phase

NCT05895747
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Low Dose 5-hydroxytryptophan, High Dose 5-hydroxytryptophan, Low Dose Creatine Monohydrate, High Dose Creatine Monohydrate, Placebo
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Not applicable Interventional

Prospective Multicenter Trial to Explore the Tolerability and Safety of the H-Coil Deep TMS in Combination With Serotonin Selective Reuptake Inhibitor(SSRI)

NCT01361815
View directory record Official record
Conditions
Major Depressive Disorder, Recurrent, Unspecified, Major Depressive Disorder, Single Episode, Unspecified
Interventions
H-Coil Deep TMS in combination with SSRIs
Device
Lead sponsor
Brainsway
Industry
Eligibility
22 Years to 68 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
13
States / cities
Davis, California • Los Angeles, California • Santa Monica, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 23, 2026, 7:50 AM EDT
Completed No phase listed Observational

Disentangling the Role of Depression in Hypersomnia

NCT05850676
View directory record Official record
Conditions
Hypersomnia
Interventions
Sleep study
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 23, 2026, 7:50 AM EDT
Recruiting Not applicable Interventional

Technology Assisted Motivational Interviewing

NCT06713603
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
TAMI Coach
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 23, 2026, 7:50 AM EDT
Terminated Not applicable Interventional Results available

Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset

NCT01842542
View directory record Official record
Conditions
Depression, Postpartum
Interventions
NeuroStar Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Neuronetics
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
8
States / cities
Hartford, Connecticut • Gainesville, Florida • Pensacola, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 23, 2026, 7:50 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Well-Mama Community Doula Navigator Study

NCT05179369
View directory record Official record
Conditions
Pregnancy Related
Interventions
Standard Care with Well-Mama Intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
15 Years to 49 Years · Female only
Enrollment
576 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Baton Rouge, Louisiana • Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Not applicable Interventional

Coil Positioning in Navigated Transcranial Magnetic Stimulation Feasibility in Depression Patients Trial

NCT03795051
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Navigated Transcranial Magnetic Stimulation
Device
Lead sponsor
Magstim
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Atlanta, Georgia • Dunwoody, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 3, 2020 · Synced Oct 23, 2026, 7:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment of Intrapartum Depression Using Non-invasive Photobiomodulation

NCT04404231
View directory record Official record
Conditions
Depression, Pregnancy Related, Intrapartum Depression
Interventions
Delivery of infrared light to the head, No Infrared treatment
Radiation · Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 23, 2026, 7:50 AM EDT
Completed No phase listed Observational

Cortical Excitability and Inhibition in MDD

NCT01718730
View directory record Official record
Conditions
Major Depressive Disorder, Recurrent, Mild, Depressive Disorder, Major
Interventions
Transcranial Magnetic Stimulation (TMS), Magnetic Resonance Spectroscopy and Imaging
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 21 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Phase 4 Interventional Results available

Combination Treatment Study for Memory Impairment and Depression

NCT01658228
View directory record Official record
Conditions
Depression, Mild Cognitive Impairment
Interventions
Donepezil, Placebo, Citalopram, Venlafaxine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
55 Years to 95 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
New York, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effectiveness of School-Based Cognitive Behavioral Therapy in Preventing Depression in Young Adolescents

NCT00360451
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Adolescent only Penn Resiliency Program (Adolescent PRP), Parent Penn Resiliency Program (Parent PRP)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2015 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Not applicable Interventional

Pilot Study in Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depression

NCT01431001
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Cervel Neurotech Deep Shaped-Field repetitive transcranial magnetic stimulator (DSF-rTMS)
Device
Lead sponsor
Cervel Neurotech, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Atlanta, Georgia • Chicago, Illinois • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Oct 23, 2026, 7:50 AM EDT
Recruiting Not applicable Interventional

The Medically Tailored Groceries and Mental Health Study

NCT07779707
View directory record Official record
Conditions
Depression / Major Depressive Disorder, Food Insecurity
Interventions
Medically Tailored, Home-delivered Groceries, Active Comparison Group: Monthly Grocery Gift Card
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 23, 2026, 7:50 AM EDT
Active, not recruiting Not applicable Interventional

A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression

NCT07112001
View directory record Official record
Conditions
HIV, Depression, Anxiety
Interventions
PositiveLinks with Counseling, Standard of Care (SOC)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 23, 2026, 7:50 AM EDT
Completed Phase 4 Interventional Results available

Safety and Efficacy of Vilazodone in Major Depressive Disorder

NCT01473381
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Vilazodone, Placebo to citalopram, Placebo to vilazodone, Citalopram
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 70 Years
Enrollment
1,162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
54
States / cities
Birmingham, Alabama • Dothan, Alabama • Scottsdale, Arizona + 46 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2014 · Synced Oct 23, 2026, 7:50 AM EDT