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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:26 PM EDT

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Showing 1–24 of 84 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Desaturation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00031

NCT03783780
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00031
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional

Combining Restrictive Guidelines and a NIRS SCORE to Decrease RBC Transfusions

NCT02535208
View directory record Official record
Conditions
Anemia of Prematurity (AOP)
Interventions
Restrictive transfusions based on SCOR assessment, Liberal transfusions
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
Up to 3 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2018 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00009

NCT03396835
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00009
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 22, 2026, 2:26 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Pulse Oximeter Accuracy During Stable Hypoxia Plateaus

NCT07408388
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse Oximeter, Induced hypoxia through breathing nitrogen-air-carbon dioxide mixture
Device · Procedure
Lead sponsor
Nihon Kohden
Industry
Eligibility
18 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional Results available

The Effect of Ventilation on Cerebral Oxygenation in the Sitting Position

NCT01546636
View directory record Official record
Conditions
Cerebral Ischemia
Interventions
Hypocapnic group, Normocapnic group
Other
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accuracy of ScanWatch Pulse Oximeter With Profound Hypoxia

NCT04380389
View directory record Official record
Conditions
Oximetry
Interventions
hypoxia
Diagnostic Test
Lead sponsor
Withings
Industry
Eligibility
18 Years to 49 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00036

NCT04002960
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00036
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Apnea Hypopnea Index Severity Versus Head Position During Sleep

NCT04086407
View directory record Official record
Conditions
Sleep Disordered Breathing, Sleep Hypopnea, Sleep Apnea, Sleep Apnea, Obstructive, Snoring
Interventions
Dual-axis inclinometer attached to the subject's forehead with tape
Device
Lead sponsor
Sleep Systems
Industry
Eligibility
21 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 22, 2026, 2:26 PM EDT
Not listed No phase listed Observational

AMBULATORY OXIMETRY MONITORING (AOM): a New Approach to Quantify Oxygen Desaturation in Ambulatory COPD Patients

NCT01873092
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Not listed
Lead sponsor
VA New York Harbor Healthcare System
Federal
Eligibility
45 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 7, 2013 · Synced Oct 22, 2026, 2:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Philps FAST2022 picoSAT Pulse Oximetry Desaturation Study

NCT05683366
View directory record Official record
Conditions
SpO2 (Peripheral Oxygen Saturation) Measurement Validation
Interventions
No Intervention
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 50 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Oct 22, 2026, 2:26 PM EDT
Completed No phase listed Observational

Pilot Study of the Feasibility of Multicenter NIRS Data Collection and Interventions for Desaturation in Cardiac Surgery

NCT01765504
View directory record Official record
Conditions
Cardiac Disease
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 22, 2026, 2:26 PM EDT
Terminated Not applicable Interventional Results available

Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery

NCT01866657
View directory record Official record
Conditions
Hypoxia
Interventions
Vasoconstrictor Agents, Head/neck repositioning, Increase ETCO2, IV fluid bolus, Additional anesthesia, RBC transfusion, Increase FiO2
Drug · Other · Biological
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
65 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional Results available

High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients

NCT03148262
View directory record Official record
Conditions
Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea, High Flow Nasal Cannula
Interventions
The Comfort Flo system, The Salter nasal cannula
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Oct 22, 2026, 2:26 PM EDT
Completed No phase listed Observational

Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea

NCT01610648
View directory record Official record
Conditions
Sleep Apnea, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2016 · Synced Oct 22, 2026, 2:26 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Controlled Desaturation Study for Perin Health Patch Validation

NCT06680700
View directory record Official record
Conditions
Oxygen Saturation Measurement
Interventions
Perin Health Patch
Device
Lead sponsor
Perin Health Devices
Industry
Eligibility
18 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Woodland Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2024 · Synced Oct 22, 2026, 2:26 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Determination of SpO2 and PR Accuracy Specifications at Rest (71Ag_Vital-0031)

NCT05297500
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse oximeter
Device
Lead sponsor
Nihon Kohden
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 22, 2026, 2:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO16)

NCT05745675
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse oximeter
Device
Lead sponsor
Nihon Kohden
Industry
Eligibility
18 Years to 50 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 22, 2026, 2:26 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00006

NCT03435211
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00006
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional

Peripheral Nerve Stimulation to Reduce Hypoxic Events

NCT02554110
View directory record Official record
Conditions
Apnea, Hypoventilation, Hypoxemia
Interventions
Stimulator active device, Stimulator sham Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Oct 22, 2026, 2:26 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cerebral Oxygen Monitoring During Surgery and Recovery After Surgery in Patients Having Lung Surgery

NCT01835327
View directory record Official record
Conditions
Cerebral Oxygen Desaturation
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Oct 22, 2026, 2:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study

NCT04559763
View directory record Official record
Conditions
Hypoxia, Desaturation of Blood
Interventions
Non-Invasive Controlled Hypoxia, Introduction of Motion conditions: tapping or rubbing
Device · Other
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 22, 2026, 2:26 PM EDT
Completed Not applicable Interventional Results available

Compression Stocking Use in Shoulder Arthroscopy in Beach Chair

NCT01996813
View directory record Official record
Conditions
Obesity, Shoulder Impingement
Interventions
Thigh-high compression stockings
Device
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 22, 2026, 2:26 PM EDT
Not listed No phase listed Observational

Identification of Desaturation Episodes by Means of Continuous Measurement of Oxygen Saturation During Hemodialysis

NCT02987179
View directory record Official record
Conditions
ESRD, Sleep Apnea, Oxygen Deficiency
Interventions
Observational
Other
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 22, 2026, 2:26 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

NCT07573150
View directory record Official record
Conditions
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
Interventions
Infrared Pupillometry
Device
Lead sponsor
NeurOptics Inc
Industry
Eligibility
3 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Francisco, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 22, 2026, 2:26 PM EDT