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Showing 1–24 of 83 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Desaturation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00038

NCT04017611
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00038
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 6, 2026, 2:59 PM EDT
Completed No phase listed Observational

Hemoglobin Desaturation in Sickle Cell Disease

NCT03908385
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 6, 2026, 2:59 PM EDT
Completed No phase listed Observational

Redesigning Cardiac Surgery to Reduce Neurologic Injury

NCT00432536
View directory record Official record
Conditions
Cardiovascular Disease, Surgery
Interventions
Quality improvement intervention
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
40 Years to 89 Years
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
3
States / cities
Portland, Maine • Lebanon, New Hampshire • Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 15, 2013 · Synced Sep 6, 2026, 2:59 PM EDT
Not listed Not applicable Interventional

SuperNO2VA™ and General Anesthesia Postoperative Care

NCT03969615
View directory record Official record
Conditions
Hypoxemia, Acute Respiratory Failure
Interventions
SuperNO2VA nasal positive airway pressure devic, Supplemental oxygen
Device
Lead sponsor
Vyaire Medical
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2019 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Results available

Compression Stocking Use in Shoulder Arthroscopy in Beach Chair

NCT01996813
View directory record Official record
Conditions
Obesity, Shoulder Impingement
Interventions
Thigh-high compression stockings
Device
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 6, 2026, 2:59 PM EDT
Completed No phase listed Observational

Pilot Study of the Feasibility of Multicenter NIRS Data Collection and Interventions for Desaturation in Cardiac Surgery

NCT01765504
View directory record Official record
Conditions
Cardiac Disease
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Accuracy Of The Owlet OSS 3.0 During Standardized Stable Hypoxia Plateaus

NCT06850610
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse oximeter accuracy under hypoxic conditions
Diagnostic Test
Lead sponsor
Owlet Baby Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00031

NCT03783780
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00031
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 6, 2026, 2:59 PM EDT
Terminated Not applicable Interventional Results available

Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery

NCT01866657
View directory record Official record
Conditions
Hypoxia
Interventions
Vasoconstrictor Agents, Head/neck repositioning, Increase ETCO2, IV fluid bolus, Additional anesthesia, RBC transfusion, Increase FiO2
Drug · Other · Biological
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
65 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced Sep 6, 2026, 2:59 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

NCT07573150
View directory record Official record
Conditions
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
Interventions
Infrared Pupillometry
Device
Lead sponsor
NeurOptics Inc
Industry
Eligibility
3 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Francisco, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 6, 2026, 2:59 PM EDT
Not listed No phase listed Observational

microEEG for Neonatal Apnea, Bradycardia and Desaturation

NCT02436616
View directory record Official record
Conditions
Apnea, Bradycardia, Premature Birth, Seizures
Interventions
microEEG
Device
Lead sponsor
Bio-Signal Group Corp.
Industry
Eligibility
Up to 30 Days
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2016 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Apnea Hypopnea Index Severity Versus Head Position During Sleep

NCT04086407
View directory record Official record
Conditions
Sleep Disordered Breathing, Sleep Hypopnea, Sleep Apnea, Sleep Apnea, Obstructive, Snoring
Interventions
Dual-axis inclinometer attached to the subject's forehead with tape
Device
Lead sponsor
Sleep Systems
Industry
Eligibility
21 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Sep 6, 2026, 2:59 PM EDT
Completed No phase listed Observational Results available

Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO18)

NCT05807464
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse Oximeter
Device
Lead sponsor
Nihon Kohden
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 6, 2026, 2:59 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00039

NCT04112784
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00039
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 6, 2026, 2:59 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00006

NCT03435211
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00006
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 6, 2026, 2:59 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cerebral Oxygen Monitoring During Surgery and Recovery After Surgery in Patients Having Lung Surgery

NCT01835327
View directory record Official record
Conditions
Cerebral Oxygen Desaturation
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prevention and Treatment of Laryngospasm and Hypoxemia Based on Risk Factors in Adult Outpatients Undergoing EGD

NCT04159116
View directory record Official record
Conditions
Laryngospasm, Hypoxemia
Interventions
Prophylactic suctioning when clinically indicated
Other
Lead sponsor
Envision Healthcare Scientific Intelligence, Inc.
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Moon Township, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 6, 2026, 2:59 PM EDT
Withdrawn Phase 4 Interventional

Ranolazine Versus Placebo Effects on Exercise Tolerance in Patients With Heart Disease and Peripheral Arterial Disease

NCT00657514
View directory record Official record
Conditions
Peripheral Arterial Disease, Angina
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
Colorado Prevention Center
Other
Eligibility
40 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 14, 2014 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00037

NCT04002973
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00037
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional

Combining Restrictive Guidelines and a NIRS SCORE to Decrease RBC Transfusions

NCT02535208
View directory record Official record
Conditions
Anemia of Prematurity (AOP)
Interventions
Restrictive transfusions based on SCOR assessment, Liberal transfusions
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
Up to 3 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspire Home Study: Utilization of Home Monitoring During Therapy Optimization in Patients With an Inspire Upper Airway Stimulation System (Comparison of Home Sleep Testing vs. In-lab Polysomnography Testing)

NCT04416542
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Home Sleep Testing
Diagnostic Test
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
22 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
5
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2022 · Synced Sep 6, 2026, 2:59 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

NCT06142019
View directory record Official record
Conditions
Hypoxia, Skin Pigmentation
Interventions
Controlled desaturation (hypoxemia)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Sep 6, 2026, 2:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Alternate Methodology of Pulse Oximeter Validation

NCT03628560
View directory record Official record
Conditions
Hypoxemia, Desaturation of Blood
Interventions
RespirAct Step-Wise Normocapnia desaturation sequence, RespirAct Slope Normocapnia desaturation sequence, RespirAct Step-Wise Hypocapnia desaturation sequence, RespirAct Slope Hypocapnia desaturation sequence, ROBD Step-Wise desaturation sequence
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 6, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation of Next Generation Cerebral and Tissue Oximeter

NCT03128372
View directory record Official record
Conditions
Oxygen Deficiency
Interventions
Desaturation
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 46 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Sep 6, 2026, 2:59 PM EDT